Search results for "MORBIDITY"

showing 10 items of 986 documents

Impact of Non-Alcoholic Fatty Liver Disease on Metabolic Comorbidities in Type 2 Diabetes Mellitus.

2021

Abstract Objective Type 2 Diabetes (T2D) is a major risk factor for the development and progression of non-alcoholic fatty liver disease (NAFLD). The published prevelance in epidemiological studies in this high risk population exceeds 70%. The aim of this analysis was to investigate the impact of NAFLD on T2D patients in Germany. Methods Using the Disease Analyzer Database (IQVIA), T2D patients with NAFLD diagnosed in Germany were matched to a cohort without NAFLD controlling for age, sex, physician, index year and metabolic comorbidities and assessed for their risk of developing myocardial infarction, stroke, peripheral arterial disease (PAD) or chronic kidney disease, as well as the type …

medicine.medical_specialtyendocrine system diseasesEndocrinology Diabetes and MetabolismPopulationType 2 diabetesComorbidity03 medical and health sciencesLiver disease0302 clinical medicineEndocrinologyNon-alcoholic Fatty Liver DiseaseRisk FactorsInternal medicineEpidemiologyInternal MedicinemedicineHumansInsulinRisk factoreducationeducation.field_of_studybusiness.industryFatty livernutritional and metabolic diseasesType 2 Diabetes MellitusGeneral Medicinemedicine.diseasedigestive system diseasesDiabetes Mellitus Type 2030220 oncology & carcinogenesis030211 gastroenterology & hepatologybusinessKidney diseaseExperimental and clinical endocrinologydiabetes : official journal, German Society of Endocrinology [and] German Diabetes Association
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Eclectic Ocular Comorbidities and Systemic Diseases with Eye Involvement: A Review.

2016

Coexistence of several ocular diseases is more frequent than suspected. In spite of the refractive errors, one or more of the following can be detected simultaneously: glaucoma, cataracts, uveitis, age-related macular degeneration, and dry eyes. In addition, as people age, ocular comorbidities are much more usually seen. Specific diseases are openly acknowledged to affect the eyes and vision, such as diabetes mellitus, hypertension blood pressure, arthritis, hyperthyroidism, neurodegenerative disorders, hematologic malignancies, and/or systemic infections. Recent advances in early diagnosis and therapy of the ophthalmic pathologies have reinforced patient options to prevent visual impairmen…

medicine.medical_specialtygenetic structuresVisual impairmentGlaucomalcsh:MedicineContext (language use)Review ArticleGeneral Biochemistry Genetics and Molecular Biologycomorbidity; humans; eye diseases03 medical and health sciences0302 clinical medicineCataractsDiabetes mellitusmedicineIntensive care medicinehumansGeneral Immunology and Microbiologybusiness.industrySettore MED/30 - Malattie Apparato Visivolcsh:Reye diseasesGeneral MedicineMacular degenerationmedicine.diseaseComorbidityeye diseasescomorbidity030221 ophthalmology & optometryPhysical therapysense organsmedicine.symptombusiness030217 neurology & neurosurgeryUveitis
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Visual Impairment Is Associated With Depressive Symptoms—Results From the Nationwide German DEGS1 Study

2018

Introduction: Visual impairment is associated with a variety of co-morbidities including physical and mental health in industrial countries. Our aim is to examine associations between self-reported impairment and depressive symptoms in the German population. Methods: The point prevalence of self-reported visual impairment in Germany was computed using data from the German Health Interview and Examination Survey for adults from 2008 to 2011 (N=7.783, 50.5% female, age range 18-79 years). Visual impairment was surveyed by two questions, one for seeing faces at a distance of 4 meters and one for reading newspapers. Depressive symptoms were evaluated with the PHQ-9 questionnaire and two-week pr…

medicine.medical_specialtygenetic structureslcsh:RC435-571Visual impairmentPopulationPrevalencevisual impairmentLogistic regressionPatient Health Questionnaire-903 medical and health sciences0302 clinical medicinedepressive symptomsreadinglcsh:PsychiatryEpidemiologyMedicine030212 general & internal medicineeducationDepression (differential diagnoses)Original ResearchPsychiatryeducation.field_of_studybusiness.industryConfoundingmedicine.diseaseComorbidityPsychiatry and Mental health030221 ophthalmology & optometryepidemiologymedicine.symptombusinessClinical psychologyface recognitionFrontiers in Psychiatry
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Cardiac arrest in older adult patients

2021

Purpose of review To describe the epidemiology, prognostication, and treatment of out- and in-hospital cardiac arrest (OHCA and IHCA) in elderly patients. Recent findings Elderly patients undergoing cardiac arrest (CA) challenge the appropriateness of attempting cardiopulmonary resuscitation (CPR). Current literature suggests that factors traditionally associated with survival to hospital discharge and neurologically intact survival after CA cardiac arrest in general (e.g. presenting ryhthm, bystander CPR, targeted temperature management) may not be similarly favorable in elderly patients. Alternative factors meaningful for outcome in this special population include prearrest functional sta…

medicine.medical_specialtyhealth care facilities manpower and servicesmedicine.medical_treatmentMEDLINE030204 cardiovascular system & hematologyTargeted temperature management03 medical and health sciences0302 clinical medicineHypothermia InducedEpidemiologyMedicineHumansCardiopulmonary resuscitationAgedResuscitation OrdersAged 80 and overAdult patientsbusiness.industry030208 emergency & critical care medicinemedicine.diseaseComorbidityhumanitiesCardiopulmonary ResuscitationHeart ArrestAnesthesiology and Pain MedicineEmergency medicineFunctional statusRisk classificationbusinessOut-of-Hospital Cardiac Arrest
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Cardiovascular Implantable Electronic Device Infection and New Insights About Correlation Between Pro-inflammatory Markers and Heart Failure: A Syste…

2021

Introduction: Surgical approaches to treat patients with abnormal pro-inflammatory parameters remain controversial, and the debate on the correlation between hematological parameter alteration in cardiac implantable electronic device (CIED) infection and the increase in mortality continues.Methods: We performed a systematic review using the PubMed, Scopus, and Cochrane Library databases. Twenty-two articles from May 2007 to April 2020 were selected and divided according to the following topics: prevalence of microbes in patients with CIED infection; characteristics of patients with CIED infection; comparison between patients who underwent and did not undergo replantation after device extrac…

medicine.medical_specialtyheart failure030204 cardiovascular system & hematologyCochrane LibraryCardiovascular Medicine03 medical and health sciences0302 clinical medicineSettore MED/43 - Medicina LegaleWhite blood cellInternal medicineEpidemiologymedicineDiseases of the circulatory (Cardiovascular) systemrisk factors030212 general & internal medicineLeukocytosisCIED infectionbusiness.industrymicrobiologyRed blood cell distribution widthmedicine.diseaseinflammatory markersComorbiditymedicine.anatomical_structureHeart failureMeta-analysisRC666-701cardiac infection CED infimammatorySystematic Reviewmedicine.symptomCardiology and Cardiovascular MedicinebusinessFrontiers in Cardiovascular Medicine
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Rehospitalization burden and morbidity risk in patients with heart failure with mid-range ejection fraction

2020

Aims Heart failure with mid-range ejection fraction (HFmrEF) has been proposed as a distinct HF phenotype, but whether patients on this category fare worse, similarly, or better than those with HF with reduced EF (HFrEF) or preserved EF (HFpEF) in terms of rehospitalization risks over time remains unclear. Methods and results We prospectively included 2961 consecutive patients admitted for acute HF (AHF) in our institution. Of them, 158 patients died during the index admission, leaving the sample size to be 2803 patients. Patients were categorized according to their EF: HFrEF if EF ≤ 40% (n = 908, 32.4%); HFmrEF if EF = 41–49% (n = 449, 16.0%); and HFpEF if EF ≥ 50% (n = 1446, 51.6%). Covar…

medicine.medical_specialtylcsh:Diseases of the circulatory (Cardiovascular) systemHeart failure030204 cardiovascular system & hematologyRecurrent events03 medical and health sciences0302 clinical medicineRisk FactorsInternal medicineCause of DeathOriginal Research ArticlesmedicineHumansIn patient030212 general & internal medicineRegistriesOriginal Research ArticleHeart FailureEjection fractionbusiness.industryMorbidity riskIncidenceHeart failure with mid-range ejection fractionStroke VolumeHeart failure with mid‐range ejection fractionmedicine.diseasePrognosisConfidence intervalReadmissionslcsh:RC666-701Heart failureCardiologyCardiology and Cardiovascular Medicinebusiness
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The Female Sex Confers Different Prognosis in Heart Failure: Same Mortality but More Readmissions

2021

Introduction: Heart failure (HF) is a major cause of morbimortality both in men and women. Differences between sex in etiopathogenesis, response to treatment, and quality of care have been found in patients with HF. Females are usually under-represented in clinical trials and there is no solid evidence demonstrating the influence of sex in the prognostic of chronic HF. The primary objective of this study was to analyse the differences in mortality and probability of hospital readmission between males and females with HF. The secondary objective was to compare mortality and probability of hospital readmission by ejection fraction (reduced vs. preserved).Methods: Patients with decompensated H…

medicine.medical_specialtylcsh:Diseases of the circulatory (Cardiovascular) systemMultivariate analysisheart failuremorbidity030204 cardiovascular system & hematologyCardiovascular Medicinereadmissions03 medical and health sciencesBasal (phylogenetics)0302 clinical medicineInternal medicinegenderMedicinesex030212 general & internal medicineOriginal ResearchHospital readmissionEjection fractionbusiness.industryFemale sexleft ventricular ejection fractionmedicine.diseaseResponse to treatmentmortalityClinical triallcsh:RC666-701Heart failureCardiologyCardiology and Cardiovascular MedicinebusinessFrontiers in Cardiovascular Medicine
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Comorbidities, Fragility, and Quality of Life in Heart Failure Patients With Midrange Ejection Fraction.

2018

Objective: To assess the effects of comorbidities, fragility, and quality of life (QOL) on long-term prognosis in ambulatory patients with heart failure (HF) with midrange left ventricular ejection fraction (HFmrEF), an unexplored area. Patients and Methods: Consecutive patients prospectively evaluated at an HF clinic between August 1, 2001, and December 31, 2015, were retrospectively analyzed on the basis of left ventricular ejection fraction category. We compared patients with HFmrEF (n=185) to those with reduced (HFrEF; n=1058) and preserved (HFpEF; n=162) ejection fraction. Fragility was defined as 1 or more abnormal evaluations on 4 standardized geriatric scales (Barthel Index, Older A…

medicine.medical_specialtylcsh:R5-920Ejection fractionbusiness.industryDepression scaleComorbidity score030204 cardiovascular system & hematologymedicine.disease03 medical and health sciences0302 clinical medicineFragilityQuality of lifeHeart failureInternal medicineAmbulatoryCardiologyMedicineGeriatric Depression Scale030212 general & internal medicinebusinesslcsh:Medicine (General)Mayo Clinic proceedings. Innovations, qualityoutcomes
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Treatment of Comorbid Alcohol Dependence and Anxiety Disorder: Review of the Scientific Evidence and Recommendations for Treatment.

2017

Producción Científica

medicine.medical_specialtylcsh:RC435-571Alcohol use disorderReviewTrastorno de ansiedadTrastorno por consumo de alcoholco-occurring disorders03 medical and health sciences0302 clinical medicinePrevalence of mental disordersanxiety disorderslcsh:Psychiatrymental disordersmedicinePsychiatryPsychiatrySertralineSocial anxietyAlcohol dependencealcohol-use disorderComorbilidadmedicine.diseaseParoxetineComorbidity030227 psychiatryPsychiatry and Mental healthcomorbiditytreatment recommendationsTrastornos concurrentesPsychology030217 neurology & neurosurgeryAnxiety disordermedicine.drugClinical psychology
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High utilizers of medical care

2004

Abstract Objective Patients with somatoform disorders (SFD) are likely to overutilize healthcare services. This study investigates (a) whether extraordinarily high medical costs can be predicted from patient characteristics or psychopathology, and (b) whether high-utilizing patients respond differently to cognitive–behavioral treatment. Methods We compared 42 SFD high utilizers with 53 SFD average utilizers and 29 patients suffering from other than SFD mental disorders. High utilization was defined by healthcare expenditures of ≥€2500 during the past 2 years. Costs were computed from medical and billing records of health insurance companies. Somatization distress, hypochondriasis, depressio…

medicine.medical_specialtymedia_common.quotation_subjectDysfunctional familymedicine.diseaseComorbidityMental healthPsychiatry and Mental healthClinical PsychologyDistressmedicinePersonalityPsychologyPsychiatryPsychosocialSomatizationPsychopathologymedia_commonJournal of Psychosomatic Research
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