Search results for "MOZ"
showing 10 items of 437 documents
Isothermal decompression history in the “Western Granulite” terrain, central Tanzania: Evidence from reaction textures and trapped fluids in metapeli…
2008
Abstract The Mozambique Belt (MB) of the East Africa Orogen contains large areas of granulite-facies migmatitic gneisses with Archaean and Palaeoproterozoic protolith ages and that were recycled during the Neoproterozoic Pan-African orogeny. The study area is situated along the Great Ruaha River and within the Mikumi National Park in central Tanzania where migmatitic gneisses and mafic to intermediate granulites are interlayered with Neoproterozoic granulite-facies migmatitic metapelites. Mineral textures suggest isothermal decompression, with the peak mineral assemblage comprising Grt–Bt–Ky–Kfs–Pl–Qtz ± Phn ± Ti-Oxide ± melt and amphibolite-facies retrograde assemblage Grt–Bt–Sil–Ms–Kfs–Pl…
The Arg/Arg polymorphism of the ADRB2 is associated with the severity of allergic asthma
2016
SINTESI ED ATTIVITÀ ANTIPROLIFERATIVA DI NUOVI DERIVATI A STRUTTURA TETRAZEPINONICA
2016
Sintesi di due nuovi composti a struttura tetrazepinonica, analoghi della Temozolomide. I due nuovi composti hanno mostrato una interessante attività antiproliferativa nei confronti di linee cellulari tumorali esprimenti l'enzima MGMT
IL PROBLEMA DELLA LEGITTIMAZIONE DELLA TUTELA PENALE NEL SISTEMA ANGLO-AMERICANO E I RIFLESSI SULLA TEORIA EUROPEO-CONTINENTALE DEL BENE GIURIDICO, C…
2012
Il bambino “sovrano” e l’adulto “irrisolto”. Tempi di crescita familiare ed educazione
2019
“Sovereign” child, apathetic adolescents, kidult, young adult, “unresolved” adult, forms of “pseudo-integrity” of the elderly are some expressions that show phenomena that are radically changing, along with the identity of the family, times of growth of the different generations, and the sense of belonging to a historical community. Profound transformations involved in the transitions of the family life cycle are also visible in the disappearance of some phases of family growth in favor of others. Through a pedagogical reflection on these phenomena, this contribution aims to underline some aspects of the ways of understanding education and growth in the family of late modernity, for the pur…
LE EMOZIONI NELLE ORGANIZZAZIONI: POSSIAMO DAVVERO IGNORARLE?
2014
Introduzione. Questo studio esplora l'importanza delle esperienze affettive dei lavoratori nel settore dei servizi, partendo dall’ipotesi di ricerca: come possono le esperienze affettive sul luogo di lavoro contribuire a spiegare gli esiti dello stress lavorativo? L’Affective Events Theory (AET) costituisce il fondamento teorico di partenza. Obiettivi e Metodi. In particolare, l’obiettivo principale del presente studio è stato quello di indagare il ruolo che gli stati affetti positivi e negativi sperimentati sul luogo di lavoro giocano come mediatori della relazione tra le caratteristiche del lavoro e gli esiti del processo dello stress lavorativo. A partire dal modello JD-R, è stato testat…
Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas
2007
AbstractIntegrative genomic and gene-expression analyses have identified amplified oncogenes in B-cell non-Hodgkin lymphoma (B-NHL), but the capability of such technologies to localize tumor suppressor genes within homozygous deletions remains unexplored. Array-based comparative genomic hybridization (CGH) and gene-expression microarray analysis of 48 cell lines derived from patients with different B-NHLs delineated 20 homozygous deletions at 7 chromosome areas, all of which contained tumor suppressor gene targets. Further investigation revealed that only a fraction of primary biopsies presented inactivation of these genes by point mutation or intragenic deletion, but instead some of them w…
Genome-wide homozygosity in Maremmana cattle
2017
The current availability of large numbers of single nucleotide polymorphisms (SNPs) throughout the genome makes these markers particularly suitable for the detection of patterns of genetic diversity and of genome-wide homozygosity in animal populations. The aim of this work was to estimate genetic diversity and homozygosity in the Maremmana cattle breed. We used a sample of 149 animals (males and females) geno-typed with the BovineSNP50 v2 (54K) Illumina BeadChip. After editing for call-rate >0.9 and removing SNP unassigned or on the sex chromosomes, 128 animals and 50,814 SNPs were left. We estimated the following genetic parameters: observed and expected heterozygosity (Ho and He), minor …
Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strat…
2021
Abstract Recent advances in human genetics, together with a large body of epidemiologic, preclinical, and clinical trial results, provide strong support for a causal association between triglycerides (TG), TG-rich lipoproteins (TRL), and TRL remnants, and increased risk of myocardial infarction, ischaemic stroke, and aortic valve stenosis. These data also indicate that TRL and their remnants may contribute significantly to residual cardiovascular risk in patients on optimized low-density lipoprotein (LDL)-lowering therapy. This statement critically appraises current understanding of the structure, function, and metabolism of TRL, and their pathophysiological role in atherosclerotic cardiova…
Homozygosity for a Mutation in the CYP11B2 Gene and GH Deficiency in a Child with Severe Growth Delay
2015
Background: Isolated hypoaldosteronism is an autosomal recessive inherited disorder of terminal aldosterone synthesis, leading to selective aldosterone deficiency. Two different biochemical forms of this disease have been described, called aldosterone synthase deficiency or corticosterone methyl oxydase, types 1 and 2. In type 1, there is no aldosterone synthase activity and the 18 hydroxycorticosterone (18 OHB) level is low, whereas in type 2, a residual activity of aldosterone synthase persists and 18 OHB is overproduced. Objective and hypotheses: Isolated aldosterone synthase deficiency should be considered in neonates and infants with failure to thrive and salt wasting. Normal levels of…