Search results for "MPL"

Modulating the DNA cleavage ability of copper(II) Schiff bases through ternary complex formation

2018

Copper(II) complexes with the potentially tridentate Schiff bases N-[(3-ethoxy-2-hydroxyphenyl)methylidene]-N′-tosylbenzene-1,2-diamine (H2L1) and N-[(2-hydroxynaphthanyl)methylidene]-N′-tosylbenzene-1,2-diamine (H2L2) have been synthesized by electrochemical oxidation of the metal in an electrochemical cell containing a solution of the corresponding ligand in acetonitrile. Adducts of these compounds with 2,2′-bipyridine (2,2′-bpy), 4,4′-bipyridine (4,4′-bpy) or 1,10-phenanthroline (phen) were also obtained. The complexes have been characterized by microanalysis, mass spectrometry, EPR, IR and UV-Vis spectroscopies, as well as DFT calculations. The ligand H2L1 and the compounds [CuL1(H2O)]·…

Remote Control by π-Conjugation of the Emissive Properties of Fischer Carbene-BODIPY Dyads.

2016

The synthesis, structure, and complete characterization of mono- and bimetallic dyads joining Fischer carbene complexes and BODIPY chromophores are reported. In these organometallic species, the Fischer carbene complex is attached to the BODIPY moiety through a p-aminophenyl group linked at the C8 carbon atom of the BODIPY core. The photophysical properties, namely the corresponding UV/vis absorption and emission spectra of these new metal-carbene complexes, are analyzed and discussed. It is found that whereas the absorption of the considered dyads strongly resembles that of the parent 4-anilinyl-substituted BODIPY, the fluorescence emission is significantly reduced in these species, very l…

The effect of bone marrow-derived stem cells associated with platelet-rich plasma on the osseointegration of immediately placed implants

2020

Background Stem cells associated with growth factors have been shown to improve bone healing and the osseointegration of dental implants. A Brazilian miniature pig model was used to evaluate the effect of autologous bone marrow-derived mesenchymal stem cells (BM-MSCs) associated with platelet-rich plasma (PRP) on the osseointegration of immediately placed dental implants. Material and methods A total of four male adult miniature pigs were used in this study. BM-MSCs from each pig were isolated from the iliac crest and expanded in vitro. The undifferentiated BM-MSCs were mixed with autologous PRP and implanted in the post-extraction sockets at the experimental sites before implant placement …

Analysis of psychoactive substances in water by information dependent acquisition on a hybrid quadrupole time-of-flight mass spectrometer.

2016

Emerging drugs of abuse, belonging to many different chemical classes, are attracting users with promises of “legal” highs and easy access via internet. Prevalence of their consumption and abuse through wastewater-based epidemiology can only be realized if a suitable analytical screening procedure exists to detect and quantify them in water. Solid-phase extraction and ultra-high performance liquid chromatography quadrupole time-of-flight-mass spectrometry (UHPLC–QqTOF–MS/MS) was applied for rapid suspect screening as well as for the quantitative determination of 42 illicit drugs and metabolites in water. Using this platform, we were able to identify amphetamines, tryptamines, piperazines, p…

A comprehensive in situ and remote sensing data set from the Arctic CLoud Observations Using airborne measurements during polar Day (ACLOUD) campaign

2019

The Arctic CLoud Observations Using airborne measurements during polar Day (ACLOUD) campaign was carried out north-west of Svalbard (Norway) between 23 May and 6 June 2017. The objective of ACLOUD was to study Arctic boundary layer and mid-level clouds and their role in Arctic amplification. Two research aircraft (Polar 5 and 6) jointly performed 22 research flights over the transition zone between open ocean and closed sea ice. Both aircraft were equipped with identical instrumentation for measurements of basic meteorological parameters, as well as for turbulent and radiative energy fluxes. In addition, on Polar 5 active and passive remote sensing instruments were installed, while Polar 6 …

Subduction or sagduction? Ambiguity in constraining the origin of ultramafic–mafic bodies in the Archean crust of NW Scotland

2016

Abstract The Lewisian Complex of NW Scotland is a fragment of the North Atlantic Craton. It comprises mostly Archean tonalite–trondhjemite–granodiorite (TTG) orthogneisses that were variably metamorphosed and reworked in the late Neoarchean to Paleoproterozoic. Within the granulite facies central region of the mainland Lewisian Complex, discontinuous belts composed of ultramafic–mafic rocks and structurally overlying garnet–biotite gneiss (brown gneiss) are spatially associated with steeply-inclined amphibolite facies shear zones that have been interpreted as terrane boundaries. Interpretation of the primary chemical composition of these rocks is complicated by partial melting and melt loss…

Cosmic-Ray Anisotropies in Right Ascension Measured by the Pierre Auger Observatory

2020

We present measurements of the large-scale cosmic-ray anisotropies in right ascension, using data collected by the surface detector array of the Pierre Auger Observatory over more than 14 years. We determine the equatorial dipole component, ~d⊥, through a Fourier analysis in right ascension that includes weights for each event so as to account for the main detector-induced systematic effects. For the energies at which the trigger efficiency of the array is small, the “East-West” method is employed. Besides using the data from the array with detectors separated by 1500 m, we also include data from the smaller but denser sub-array of detectors with 750 m separation, which allows us to extend …

Analytical Process

2016

Automatic emulator and optimized look-up table generation for radiative transfer models

2017

This paper introduces an automatic methodology to construct emulators for costly radiative transfer models (RTMs). The proposed method is sequential and adaptive, and it is based on the notion of the acquisition function by which instead of optimizing the unknown RTM underlying function we propose to achieve accurate approximations. The Automatic Gaussian Process Emulator (AGAPE) methodology combines the interpolation capabilities of Gaussian processes (GPs) with the accurate design of an acquisition function that favors sampling in low density regions and flatness of the interpolation function. We illustrate the good capabilities of the method in toy examples and for the construction of an…

Multioutput Automatic Emulator for Radiative Transfer Models

2018

This paper introduces a methodology to construct emulators of costly radiative transfer models (RTMs). The proposed methodology is sequential and adaptive, and it is based on the notion of acquisition functions in Bayesian optimization. Here, instead of optimizing the unknown underlying RTM function, one aims to achieve accurate approximations. The Automatic Multi-Output Gaussian Process Emulator (AMO-GAPE) methodology combines the interpolation capabilities of Gaussian processes (GPs) with the accurate design of an acquisition function that favors sampling in low density regions and flatness of the interpolation function. We illustrate the promising capabilities of the method for the const…