Search results for "MR"

showing 10 items of 3001 documents

Towards Translational ImmunoPET/MR Imaging of Invasive Pulmonary Aspergillosis: The Humanised Monoclonal Antibody JF5 Detects Aspergillus Lung Infect…

2017

Invasive pulmonary aspergillosis (IPA) is a life-threatening lung disease of hematological malignancy or bone marrow transplant patients caused by the ubiquitous environmental fungus Aspergillus fumigatus. Current diagnostic tests for the disease lack sensitivity as well as specificity, and culture of the fungus from invasive lung biopsy, considered the gold standard for IPA detection, is slow and often not possible in critically ill patients. In a previous study, we reported the development of a novel non-invasive procedure for IPA diagnosis based on antibody-guided positron emission tomography and magnetic resonance imaging (immunoPET/MRI) using a [64Cu] DOTA-labeled mouse monoclonal anti…

dota0301 basic medicinePathologyMonoclonal AntibodyMedizininflammatory diseasesMedicine (miscellaneous)ImmunoPET/MRI.AcetatesAspergillosisEpitopeAspergillus fumigatusMicepet/mriCricetinaeMedicine[ SDV.IB ] Life Sciences [q-bio]/BioengineeringPharmacology Toxicology and Pharmaceutics (miscellaneous)biologyMagnetic Resonance Imaging3. Good healthInfectious DiseasesAspergillus/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being[SDV.IB]Life Sciences [q-bio]/BioengineeringFemaleAntibodyrevealsResearch Papermedicine.medical_specialtymedicine.drug_class030106 microbiologyLung biopsyCHO CellsMonoclonal antibodyAntibodies Monoclonal HumanizedAspergillus nidulans03 medical and health sciencesHeterocyclic Compounds 1-RingCricetulusSDG 3 - Good Health and Well-beingAntigenIn vivo[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathologygalactofuranoseAspergillosisAnimalsImmunoPET/MRIAntibodies FungalInfectious Diseases; Aspergillus; Aspergillosis; Monoclonal Antibody; JF5; ImmunoPET/MRIbusiness.industryfumigatusmedicine.diseasebiology.organism_classificationMice Inbred C57BLCopper RadioisotopesJF5Positron-Emission Tomographybiology.proteinbiosynthesisRadiopharmaceuticalsbusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyTheranostics
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Studies of network structure and dynamics of e-beam crosslinked PVPs: From macro to nano

2011

Much interest has been paid to develop a variety of radiation-crosslinked hydrated polymeric materials, which swell in water but do not dissolve, as biocompatible materials used for wound healing, drug delivery system, surface-coating material for medically used devices, etc. With the aim of establishing design rules to produce hydrogels of controlled size at the nanoscale and desired internal network structure using conventional electron accelerators and set-ups, here we attempt a description in terms of structural and dynamic properties of polymer networks generated through e-beam irradiation of aqueous solutions of the same model polymer, a commercial grade poly(N-vinyl-pyrrolidone), sub…

e-Beam irradiationPVP aqueous solutions Nanogels Dynamic mechanical spectroscopy NMR spin–lattice relaxation
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Optical investigation of spin-crossover in cobalt(II) bis-terpy complexes

2007

Abstract The spin transition of the [Co(terpy) 2 ] 2+ complex (terpy = 2,2′:6′,2″-terpyridine) is analysed based on experimental data from optical spectroscopy and magnetic susceptibility measurements. The single crystal absorption spectrum of [Co(terpy) 2 ](ClO 4 ) 2 shows an asymmetric absorption band at 14 400 cm −1 with an intensity typical for a spin-allowed d–d transition and a temperature behaviour typical for a thermal spin transition. The single crystal absorption spectra of suggest that in this compound, the complex is essentially in the high-spin state at all temperatures. However, the increase in intensity observed in the region of the low-spin MLCT transition with increasing te…

education.field_of_studyAbsorption spectroscopyChemistryPopulationRelaxation (NMR)Analytical chemistrySpin transitionMagnetic susceptibilityInorganic ChemistryCrystallographyAbsorption bandSpin crossoverddc:540Materials ChemistryCondensed Matter::Strongly Correlated ElectronsPhysical and Theoretical ChemistryeducationSingle crystalInorganica Chimica Acta
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Transition-Selective Pulses in Zero-Field Nuclear Magnetic Resonance.

2016

We use low-amplitude, ultralow frequency pulses to drive nuclear spin transitions in zero and ultralow magnetic fields. In analogy to high-field NMR, a range of sophisticated experiments becomes available as these allow narrow-band excitation. As a first demonstration, pulses with excitation bandwidths 0.5–5 Hz are used for population redistribution, selective excitation, and coherence filtration. These methods are helpful when interpreting zero- and ultralow-field NMR spectra that contain a large number of transitions.

education.field_of_studyChemistryPopulationSelective excitation010402 general chemistry7. Clean energy01 natural sciences0104 chemical sciencesMagnetic fieldNMR spectra databaseNuclear magnetic resonanceZero field0103 physical sciencesPhysical and Theoretical Chemistry010306 general physicseducationExcitationCoherence (physics)The journal of physical chemistry. A
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Ab initio calculations of CaZrO3 (011) surfaces: systematic trends in polar (011) surface calculations of ABO3 perovskites

2019

Financial support via Latvian-Ukrainian Joint Research Project No. LV-UA/2018/2 for A. I. Popov, Latvian Council of Science Project No. 2018/2-0083 “Theoretical prediction of hybrid nanostructured photocatalytic materials for efficient water splitting” for R. I. Eglitis and J. Kleperis as well as ERAF project No. 1.1.1.1/18/A/073 for R. I. Eglitis and J. Purans is greatly acknowledged.

education.field_of_studyMaterials science020502 materialsMechanical EngineeringPopulationRelaxation (NMR)Ab initio02 engineering and technologyMolecular physicsCrystal0205 materials engineeringChemical bondMechanics of MaterialsAb initio quantum chemistry methods:NATURAL SCIENCES:Physics [Research Subject Categories]PolarGeneral Materials ScienceeducationPerovskite (structure)Journal of Materials Science
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Pyrene, a Test Case for Deep-Ultraviolet Molecular Photophysics

2019

We determined the complete relaxation dynamics of pyrene in ethanol from the second bright state, employing experimental and theoretical broadband heterodyne detected transient grating and two-dimensional photon echo (2DPE) spectroscopy, using pulses with duration of 6 fs and covering a spectral range spanning from 250 to 300 nm. Multiple lifetimes are assigned to conical intersections through a cascade of electronic states, eventually leading to a rapid population of the lowest long-living excited state and subsequent slow vibrational cooling. The lineshapes in the 2DPE spectra indicate that the efficiency of the population transfer depends on the kinetic energy deposited into modes requir…

education.field_of_studyMaterials sciencePhotonLetter010304 chemical physicsPopulationRelaxation (NMR)Conical intersection010402 general chemistryKinetic energy01 natural sciencesMolecular physicsSpectral line0104 chemical sciencespyrene 2D-UV computational spectroscopy computational photochemistryExcited state0103 physical sciencesGeneral Materials SciencePhysical and Theoretical ChemistryeducationSpectroscopy
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ChemInform Abstract: Theoretical and Spectroscopic Studies on Imino-Carbon Palladated Pyridine-2-carbaldimines.

1987

Abstract Ab initio LCAO-MO-SCF calculations on the model compounds C 5 H 4 N-2-C(R 1 )=NH [R 1 = H ( 2c ) and R 1 = trans -PdCl(PH 3 ) 2 ( 4c )] indicate that the E - trans conformation is favored over the E - cis one by 16.9 kJ mol −1 for 2c and by 25.0 kJ mol −1 for 4c . One of the factors which stabilizes the E-trans arrangement for 4c is a weak bonding interaction between the palladium center and the pyridine nitrogen. On going from 2c to 4c a slight charge enrichment on the pyridine carbons and a more pronounced one on the nitrogen atoms is computed, whereas the charge density of the imino carbon atom is decreased. In 4c no π contribution to the PdC bond is observed. Protonation of th…

education.field_of_studyPopulationAb initiochemistry.chemical_elementProtonationGeneral MedicineCarbon-13 NMRchemistry.chemical_compoundCrystallographychemistryPyridineMoietyeducationHOMO/LUMOPalladiumChemInform
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Influence of Bond Fixation in Benzo-Annulated N-Salicylideneanilines and Their ortho-C(O)X Derivatives (X = CH3, NH2, OCH3) on Tautomeric Equilibria …

2007

1H, 13C, and 15N NMR spectra show that an ortho-C(=O)X group present in the molecules of N-salicylideneanthranilamide (X = NH2), methyl N-salicylideneanthranilate (X = OCH3), N-salicylidene-o-aminoacetophenone (X = CH3), and their benzo analogues have only a minor effect on the tautomeric OH/NH-equilibrium in solution. Only two of three possible tautomers were detected. Lability of the absent form was proved by theoretical calculations. Calculated energies show that the enolimino form (OH) is less stable than the enaminone (NH) form only for dibenzo-annulated N-salicylideneanilines. The population of each species in the tautomeric mixture was found to be inversely proportional to its energy…

education.field_of_studyStereochemistryHydrogen bondOrganic ChemistryCarbon-13PopulationAromaticityTautomerEnolNMR spectra databaseCrystallographychemistry.chemical_compoundchemistryMoleculeeducationThe Journal of Organic Chemistry
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Chapter 4 3D brainstem topodiagnosis – a voxel-based model analyzing MR imaging data

2006

Publisher Summary This chapter presents a new method of statistically based three-dimensional (3D) brainstem mapping to identify brainstem structures responsible for specific clinical and electrophysiological abnormalities. To ensure reliable correlations, a large cohort of patients with magnetic resonance (MR)-documented brainstem infarctions were recruited in two European neurological institutions—namely, the Department of Neurology, Johannes Gutenberg University, Mainz, Germany, and the Department of Neurological Sciences, “La Sapienza” University of Rome, Italy. This method minimizes the risk of highlighting vascular territories rather than the structures specifically responsible for th…

education.field_of_studymedicine.medical_specialtyNeurologymedicine.diagnostic_testbusiness.industryPopulationMagnetic resonance imagingcomputer.software_genreBrain mappingMr imagingVoxelMedicineBrainstembusinesseducationcomputerNeuroscienceVascular supply
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CT and MR Imaging of Brain Tumors

1989

Our clinical population numbered 8516 patients with primary and metastatic brain tumors who underwent evaluation by computed tomography at the neurosurgical and neuroradiologic departments of the Berlin, Mainz, and Munich centers from 1975 to 1986 and at the Neurosurgical Department of Augsburg Central Hospital from 1983 to 1986. Table 5 lists all the tumors having an incidence greater than 1% in the total population; 98% of the lesions were confirmed histologically (open surgery, stereotactic biopsy, autopsy). “Rare” intracranial tumors having an incidence no greater than 1% are listed in Table 6. The frequencies of the individual tumor types correlate well with the statistical data report…

education.field_of_studymedicine.medical_specialtyStereotactic biopsymedicine.diagnostic_testbusiness.industryOpen surgeryIncidence (epidemiology)PopulationAutopsyTotal populationMr imaginghumanitiesmedicineRadiologyeducationNeurosurgical departmentbusiness
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