Search results for "MR"
showing 10 items of 3001 documents
Trans-cranial MRI-guided Focused Ultrasound Surgery (tcMRgFUS): preliminary Italian (and world-first) experience at 1,5 Tesla.
2015
PURPOSE: We present our preliminary results achieved with the first Italian installation of a trans-cranial MRI-guided Focused Ultrasound Surgery (tcMRgFUS) certified system for functional neurosurgery. Moreover, to our knowledge, this is the world-first tcMRgFUS system ever installed on a 1.5T MRI unit. Technical issues faced to achieve a safe and effective treatment will be discussed focusing on MR high-resolution live imaging and thermometry sequences optimization. METHOD AND MATERIALS: Patient enrollment was based on indication for functional neurosurgery and evidence of medication-refractory disease; a detailed medical history has been collected together with a complete clinical examin…
Chirurgia trans-cranica mediante ultrasuoni focalizzati ad alta intensità su guida rm: esperienza preliminare a 1,5T (primi 2 casi trattati)
2015
Scopo del Lavoro Presentiamo i risultati preliminari ottenuti con la prima istallazione italiana di un’apparecchiatura per la neurochirurgia funzionale mediante ultrasuoni focalizzati ad alta intensità su guida RM (trans-cranial MRI-guided Focused Ultrasound Surgery, tcMRgFUS); si tratta tra l’altro della prima apparecchiatura tcMRgFUS al mondo mai installata su uno scanner RM da 1,5T. Tale apparecchiatura è attualmente certificata (CE ed FDA) per trattamenti di neurochirurgia funzionale in pazienti con tremore essenziale (Essential Tremor, ET), Parkinson idiopatico (Parkinson Disease, PD) unilaterale prevalentemente tremorigeno e dolore neuropatico (Neuropathic Pain, NP). Materiali e Metod…
Chirurgia trans-cranica mediante ultrasuoni focalizzati ad alta intensità su guida RM: esperienza preliminare a 1,5T (prima paziente trattata)
2015
Presentiamo i risultati preliminari ottenuti con la prima istallazione italiana di un’apparecchiatura per la neurochirurgia funzionale mediante ultrasuoni focalizzati ad alta intensità su guida RM (trans-cranial MRI-guided Focused Ultrasound Surgery, tcMRgFUS); si tratta tra l’altro della prima apparecchiatura tcMRgFUS al mondo mai installata su uno scanner RM da 1,5T. Tale apparecchiatura è destinata a trattamenti di neurochirurgia funzionale di pazienti con tremore essenziale (Essential Tremor, ET), Parkinson idiopatico (Parkinson Disease, PD) prevalentemente tremorigeno e dolore neuropatico (Neuropa- thic Pain, NP). Sanno presentati i risultati ottenuti con i primi pazienti sottoposti …
POST-THALAMOTOMY NEUROFUNCTIONAL FINDINGS ON PATIENTS TREATED WITH TRANS-CRANIAL MAGNETIC RESONANCE GUIDED FOCUSED ULTRASOUND SURGERY (TCMRGFUS): PRE…
2015
BACKGROUND AND PURPOSE: We present functional connectivity (FC) changes found in the very first patients treated with the first Italian installation of a trans-cranial MRI-guided Focused Ultrasound Surgery (tcMRgFUS) certified system for functional neurosurgery. TcMRgFUS is a promising new technique for non-invasive treatment of neurologic disorders such as Essential Tremor, tremor associated to Parkinson's Disease and Neuropathic Pain. TcMRgFUS is able to focally target and destroy specific regions in the brain through intact skull, by using a high intensity focused ultrasound beam. Resting state functional Magnetic Resonance Imaging (RS-fMRI) analyses focuses on spontaneous low frequency …
Sviluppo di Metodologie e di Analisi per Tecniche Avanzate di Risonanza Magnetica
2020
SORVEGLIANZA DELLE COLONIZZAZIONI DA STAPHYLOCOCCUS AUREUS METICILLINO-RESISTENTE E GRAM-NEGATIVI MULTI-RESISTENTI NELLE UNITA’ DI TERAPIA INTENSIVA …
2014
INTRODUZIONE: La diffusione della resistenza batterica, sia in ospedale che in comunità, costituisce un serio motivo di allarme. La disseminazione di microrganismi resistenti in ospedale, particolarmente accentuata in reparti critici quali le terapie intensive, è favorita oltre che dall’uso dei farmaci antimicrobici, da procedure chirurgiche e/o invasive, dalla presenza di pazienti compromessi e dal trasferimento da una struttura sanitaria ad un’altra di pazienti colonizzati o infetti. Una conoscenza dettagliata dell’entità del fenomeno e dei principali microrganismi antibiotico-resistenti in ambito nosocomiale è essenziale per lo sviluppo di strategie volte a prevenire tale fenomeno. In qu…
Nanosystem for diagnosis and photothermal treatment of tumors
2022
The invention relates to a nanosystem for the diagnosis, image-guided treatment of tumors and monitoring of the tumor microenvironment. The nanosystem is a contrast agent comprising a polymer shell based on a hyaluronic acid nanogel, super-parameg-netic iron oxide nanoparticles (SPIONs) and carbon nanoparticles (CDs).
Study of the curing of a DGEBA based system through structural investigation
2011
An extended catalogue of ncRNAs in Streptomyces coelicolor reporting abundant tmRNA, RNase-P RNA and RNA fragments derived from pre-ribosomal RNA lea…
2022
Streptomyces coelicolor is a model organism for studying streptomycetes. This genus possesses relevant medical and economical roles, because it produces many biologically active metabolites of pharmaceutical interest, including the majority of commercialized antibiotics. In this bioinformatic study, the transcriptome of S. coelicolor has been analyzed to identify novel RNA species and quantify the expression of both annotated and novel transcripts in solid and liquid growth medium cultures at different times. The major characteristics disclosed in this study are: (i) the diffuse antisense transcription; (ii) the great abundance of transfer-messenger RNAs (tmRNA); (iii) the abundance of rnpB…
Predicting Individual Differences from Brain Responses to Music using Functional Network Centrality
2022
Individual differences are known to modulate brain responses to music. Recent neuroscience research suggests that each individual has unique and fundamentally stable functional brain connections irrespective of the task they perform. 77 participants’ functional Magnetic Resonance Imaging (fMRI) responses were measured while continuously listening to music. Using a graph-theory-based approach, we modeled whole-brain functional connectivity. We then calculate voxel-wise eigenvector centrality and subsequently use it to classify gender and musical expertise using binary Support Vector Machine (SVM). We achieved a cross-validated classification accuracy of 97% and 96% for gender and musical exp…