Search results for "MR"

showing 10 items of 3001 documents

Synthesis, spectroscopic characterization and antiproliferative activity of two platinum(II) complexes containing N-donor heterocycles

2014

Abstract Novel mononuclear complexes of Pt(II), cis -[PtCl 2 (DMSO)HL]·2DMSO ( 1 ), where HL = 7-amino-2-(methylthio)[1,2,4]triazolo[1,5- a ]pyrimidine-6-carboxylic acid and Pt(bdt)Cl 2 ( 2 ), where bdt = [2,4-bis(5,6-diphenyl-1,2,4-triazin-3yl)-pyridine] have been synthesized and characterized by elemental analysis, IR and 1 H NMR spectroscopy and X-ray crystallography diffraction analyses. The molecular structure of ( 1 ) shows that Pt(II) ion has a square planar geometry with N(3) bonded heterocycle ligand, two cis chloride anions and S-bonded dimethylsulfoxide. The antiproliferative activity of complexes ( 1 ) and ( 2 ) has been tested in vitro against HepG2 human hepatoma cells and non…

CisplatinLigandChemistryStereochemistrychemistry.chemical_elementPhosphatidylserineIn vitroMononuclear platinum complexes Heterocyclic nitrogen Dimethylsulfoxide Antitumor activityAntitumor activity Dimethylsulfoxide Heterocyclic nitrogen Mononuclear platinum complexesDimethylsulfoxide Heterocyclic nitrogen Mononuclear platinum complexesInorganic Chemistrychemistry.chemical_compoundMembraneSettore CHIM/03 - Chimica Generale E InorganicaMaterials ChemistryProton NMRmedicineMoleculePhysical and Theoretical ChemistryPlatinumAntitumor activitymedicine.drugInorganica Chimica Acta
researchProduct

The metabolic profile of lemon juice by proton HR-MAS NMR: the case of the PGI Interdonato Lemon of Messina

2015

We have studied by means of High Resolution Magic Angle Spinning Nuclear Magnetic Resonance (HR-MAS NMR) the metabolic profile of the famous Sicilian lemon known as 'Interdonato Lemon of Messina PGI'. The PGI Interdonato Lemon of Messina possesses high organoleptic and healthy properties and is recognised as one of the most nutrient fruits. In particular, some of its constituents are actively studied for their chemo-preventive and therapeutic properties. In this paper, we have determined by means of HR-MAS NMR spectroscopy the molar concentration of the main metabolites constituent the juice of PGI Interdonato Lemon of Messina in comparison with that of the not-PGI Interdonato Lemon of Turk…

CitrusMagnetic Resonance SpectroscopyTurkeyOrganolepticHigh resolutionmetabolic fingerprintPlant ScienceBiochemistryAnalytical ChemistryPlant scienceMagic angle spinningFood scienceAmino AcidsSicilyHR-MAS NMR; lemon citrus; metabolomics; food science; Sicily; metabolic fingerprintInternational marketChemistrylemon citruFatty AcidsOrganic ChemistryNuclear magnetic resonance spectroscopyBiochemistryFruitMetabolomeHR-MAS NMRLemon juicefood scienceFood AnalysisMetabolic profilemetabolomic
researchProduct

7 Tesla MRI will soon be helpful to guide clinical practice in multiple sclerosis centres – No

2021

Clinical Practicemedicine.medical_specialtyText miningNeurologybusiness.industryMultiple sclerosisMEDLINEMedicine7 tesla mriMedical physicsNeurology (clinical)businessmedicine.diseaseMultiple Sclerosis Journal
researchProduct

Multicenter stability of diffusion tensor imaging measures: a European clinical and physical phantom study.

2011

Diffusion tensor imaging (DTI) detects white matter damage in neuro-psychiatric disorders, but data on reliability of DTI measures across more than two scanners are still missing. In this study we assessed multicenter reproducibility of DTI acquisitions based on a physical phantom as well as brain scans across 16 scanners. In addition, we performed DTI scans in a group of 26 patients with clinically probable Alzheimer's disease (AD) and 12 healthy elderly controls at one single center. We determined the variability of fractional anisotropy (FA) measures using manually placed regions of interest as well as automated tract based spatial statistics and deformation based analysis. The coefficie…

Coefficient of variationNeuroscience (miscellaneous)Nerve Fibers MyelinatedBrain mappingImaging phantommethods [Diffusion Tensor Imaging]White matterYoung AdultNeuroimagingBiasAlzheimer Diseasepathology [Brain]Fractional anisotropymedicineHumansRadiology Nuclear Medicine and imagingddc:610AgedAged 80 and overReproducibilityBrain Mappingpathology [Nerve Fibers Myelinated]business.industryPhantoms Imagingdiagnosis [Alzheimer Disease]BrainMiddle AgedEuropePsychiatry and Mental healthDiffusion Tensor Imagingmedicine.anatomical_structureAnisotropyFemaleNuclear medicinebusinessPsychologyDiffusion MRI
researchProduct

Trait impulsivity associated with altered resting-state functional connectivity within the somatomotor network

2020

Knowledge of brain mechanisms underlying self-regulation can provide valuable insights into how people regulate their thoughts, behaviors, and emotional states, and what happens when such regulation fails. Self-regulation is supported by coordinated interactions of brain systems. Hence, behavioral dysregulation, and its expression as impulsivity, can be usefully characterized using functional connectivity methodologies applied to resting brain networks. The current study tested whether individual differences in trait impulsivity are reflected in the functional architecture within and between resting-state brain networks. Thirty healthy individuals completed a self-report measure of trait im…

Cognitive NeuroscienceSensory systemSomatosensory systemImpulsivitylcsh:RC321-57103 medical and health sciencesBehavioral Neuroscience0302 clinical medicineBarratt Impulsiveness Scalemedicineresting statelcsh:Neurosciences. Biological psychiatry. NeuropsychiatryOriginal Research030304 developmental biology0303 health sciencestrait impulsivitymedicine.diagnostic_testResting state fMRIFunctional connectivityfunctional connectivitysomatomotor networkNeuropsychology and Physiological PsychologyTraitBarratt Impulsiveness Scalemedicine.symptomPsychologyFunctional magnetic resonance imagingNeuroscience030217 neurology & neurosurgeryNeuroscience
researchProduct

Influence of Musical Expertise on the processing of Musical Features in a Naturalistic Setting

2019

Musical training causes structural and functional changes in the brain due to its sensory-motor demands, but the modulatory effect of musical training on music feature processing in the brain in a continuous music listening paradigm, has not been investigated thus far. In this work, we investigate the differences between musicians and non-musicians in the encoding of musical features encompassing musical timbre, rhythm and tone. 18 musicians and 18 non-musicians were scanned using fMRI while listening to 3 varied stimuli. Acoustic features corresponding to timbre, rhythm and tone were computationally extracted from the stimuli and correlated with brain responses, followed by t-tests on grou…

Cognitive sciencemuusikotneuropsykologiafMRInaturalistic stimulusmusiikkipsykologiaMusicalacoustic feature extractionbehavioral disciplines and activitieshumanitiestoiminnallinen magneettikuvausprosessointimusicians vs non-musiciansmusic processingPsychologyärsykkeetNaturalism2019 Conference on Cognitive Computational Neuroscience
researchProduct

Decreased temperature increases the expression of a disordered bacterial late embryogenesis abundant (LEA) protein that enhances natural transformati…

2021

Late embryogenesis abundant (LEA) proteins are important players in the management of responses to stressful conditions, such as drought, high salinity, and changes in temperature. Many LEA proteins do not have defined three-dimensional structures, so they are intrinsically disordered proteins (IDPs) and are often highly hydrophilic. Although LEA-like sequences have been identified in bacterial genomes, the functions of bacterial LEA proteins have been studied only recently. Sequence analysis of outer membrane interleukin receptor I (BilRI) from the oral pathogen Aggregatibacter actinomycetemcomitans indicated that it shared sequence similarity with group 3/3b/4 LEA proteins. Comprehensive …

Cold shock proteinEmbryonic DevelopmentInfectious and parasitic diseasesRC109-216Aggregatibacter actinomycetemcomitansbakteeritkylmänkestävyysNMR spectroscopyBacterial Proteinsnmr spectroscopyDNA transformation competencelate embryogenesis abundant proteinHumansNMR-spektroskopiaPlant Proteinsaggregatibacter actinomycetemcomitanscold shock proteinlate embryogenesisBiochemistry and Molecular BiologyTemperatureIntrinsically Disordered Proteinsabundant proteindna transformation competencelämpötilaproteiinitBiokemi och molekylärbiologiResearch ArticleResearch PaperVirulence
researchProduct

Colonizzazione da Staphylococcus Aureus Meticillino-Resistente (MRSA) in epoca di vita neonatale nell’U.O. Neonatologia e TIN dell’AOUP “P.Giaccone” …

2015

Colonizzazione, MRSA, UTIN

Colonizzazione MRSA UTIN
researchProduct

MR imaging of bilateral paramedian thalamic and mesencephalic infarcts: A case report

2010

We describe MR imaging of bilateral infarction of the paramedian portion of the mesencephalus and thalamus due to an occlusion of the Percheron artery. This entity is due to one of the anatomic variants of the perforating arteries supplying the thalamus and mesenchephalus. Clinically this kind of infarction presents with neurologic impairment as a disorder of consciousness, memory dysfunctions, various types of vertical gaze palsy and psychic changes, which need to be differentiated from delirium and coma. At MRI evaluation infarction of the paramedian portion of thalami and midbrain, with a “butterfly wings” pattern, was demonstrated as high signal intensity areas on FLAIR and FSE-T2W ima…

Comamedicine.medical_specialtyPalsybusiness.industryThalamusInfarctionGeneral MedicineAnatomyFluid-attenuated inversion recoverymedicine.diseaseSurgeryMidbrainPerforating arteriesmedicine.arteryOcclusionNONEmedicinePercheron artery MR Brain IschemiaRadiology Nuclear Medicine and imagingcardiovascular diseasesNeurology (clinical)medicine.symptombusiness
researchProduct

Comment on “Medication-Related Osteonecrosis of the Jaw (MRONJ)” by Elie M. Ferneini in the Section “Simply Put: JOMS Information for Patients”

2021

We read with great interest the contribute to the section “Simply Put: JOMS Information for Patients” named “Medication-Related Osteonecrosis of the Jaw (MRONJ)” by Elie M. Ferneini.

Comment medication-related osteonecrosis of the jaw mronj
researchProduct