Search results for "MRI"

Sviluppo di un software per l’analisi di immagini di Diffusion Kurtosis Imaging

2013

L’analisi mediante RM del tensore di diffusione (Diffusion Tensor Imaging, DTI) consente di valutare anche in vivo e con modalità non invasive il processo di diffusione delle molecole d’acqua nei tessuti biologici. La peculiare organizzazione di alcuni tessuti biologici (es: muscoli, sostanza bianca del sistema nervoso centrale e tessuti ad alta cellularità) influenza tale fenomeno rendendolo anisotropo e quindi ben valutabile con tali tecniche di studio. Nonostante i grandi vantaggi di tale tecnica, il DTI è basato su un modello molto semplificato che assume che lo spostamento per diffusione segua un profilo gaussiano il che è molto raro in un ambiente variegato come i tessuti biologic…

Trans-cranial Magnetic Resonance-guided Focused UltraSound (tcMRgFUS) system integrated with a 1.5T: an SNR study on DQA phantoms

2018

Background: In recent years transcranial Magnetic Resonance-guided Focused Ultrasound Surgery (tcMRgFUS) treatments have been performed only using 3T units. Since following some internal analysis, planning images obtained using a 1.5T MRI’s body RF coil (as usually done with 3T systems) showed generally reasonable quality in terms of anatomy visualization and SNR but thermal images noise was above acceptable standard for treatments, a dedicated 2-channels head coil was developed (InSightec Ltd.) to ensure an adequate signal-to-noise ratio (SNR). Hence, we present the imaging protocol and the technological methods successfully used with the world-first installation of a certified tcMRgFUS sy…

Towards Translational ImmunoPET/MR Imaging of Invasive Pulmonary Aspergillosis: The Humanised Monoclonal Antibody JF5 Detects Aspergillus Lung Infect…

2017

Invasive pulmonary aspergillosis (IPA) is a life-threatening lung disease of hematological malignancy or bone marrow transplant patients caused by the ubiquitous environmental fungus Aspergillus fumigatus. Current diagnostic tests for the disease lack sensitivity as well as specificity, and culture of the fungus from invasive lung biopsy, considered the gold standard for IPA detection, is slow and often not possible in critically ill patients. In a previous study, we reported the development of a novel non-invasive procedure for IPA diagnosis based on antibody-guided positron emission tomography and magnetic resonance imaging (immunoPET/MRI) using a [64Cu] DOTA-labeled mouse monoclonal anti…

Feasibility in routine clinical setting of combined resting-state fMRI and DTI-tractography for surgical planning of brain tumors

2020

Purpose Methods and materials Results Conclusion Personal information and conflict of interest References

FUNCTIONAL CONNECTIVITY MODULATION INDUCED BY TRANSCRANIAL DIRECT CURRENT STIMULATION OF THE MOTOR NETWORK

2015

Background: Brain functions arise from the orchestrated activation and cooperation of networks of regions whose specific relationship varies dynamically across functional states. Resting state functional Magnetic Resonance Imaging (RS-fMRI) analyses focuses on spontaneous low frequency fluctuations (< 0.1 Hz) in the BOLD signal and investigates synchronous activations between regions that are spatially distinct (functional connectivity, FC), occurring in the absence of a task or stimulus. Transcranial Direct Current Stimulation (tDCS) is a non-invasive brain stimulation technique that is known to modulate cortical activity and FC among brain regions, as measured by functional Magnetic Reson…

First-Episode Psychotic Patients Showed Longitudinal Brain Changes Using fMRI With an Emotional Auditory Paradigm

2020

Most previous longitudinal studies of functional magnetic resonance imaging (fMRI) in first-episode psychosis (FEP) using cognitive paradigm task found an increased activation after antipsychotic medications. We designed an emotional auditory paradigm to explore brain activation during emotional and nonemotional word processing. This study aimed to analyze if longitudinal changes in brain fMRI BOLD activation is present in patients vs. healthy controls. A group of FEP patients (n = 34) received clinical assessment and had a fMRI scan at baseline and follow-up (average, 25-month interval). During the fMRI scan, both emotional and nonemotional words were presented as a block design. Results w…

NUCLEAR MAGNETIC RESONANCE RELAXOMETRY AND IMAGING FOR DOSIMETRY WITH AGAROSE FRICKE GEL

2016

Introduction: Fricke Xylenol Gel (FXG) dosimetric system is based on the radiation induced oxidation of ferrous to ferric ions. In this kind of gels it can occur that ferrous and ferric ions diffuse in the gel matrix. To preserve the spatial distribution of the dose from diffusion, Fricke gels must be undergoing measurement within a few hours of their irradiation. Thus, the spatial integrity of the dose distribution in the Fricke gel is maintained. The oxidation of ferrous ions also causes a reduction of the longitudinal nuclear magnetic relaxation time which can be measured by means of nuclear magnetic resonance (NMR) instrumentation. In this work we performed NMR relaxometry and MR imagin…

New Fricke gel with high sensitivity and low diffusion for 3D-MRI dosimetry

2018

Intrabiliary rupture of hepatic hydatid cyst: MRI findings

2016

Learning objectives Background Findings and procedure details Conclusion Personal information References

Long-term evolution of hepatocellular adenomas at MRI follow-up

2021

Background Hepatocellular adenomas (HCAs) are rare benign liver tumors. Guidelines recommend continued surveillance of patients diagnosed with HCAs, but these guidelines are mainly based on small studies or expert opinion. Purpose To analyze the long-term evolution of HCAs, including solitary and multiple lesions, and to identify predictive features of progression with MRI. Materials and Methods In a retrospective study, patients diagnosed with pathologically proven solitary or multiple HCAs between January 2004 and December 2015 were included; β-catenin-mutated HCAs and HCAs with foci of malignancy were considered to be at risk for progression. MRI examinations were analyzed, and tumor evo…