Search results for "MSE"
showing 10 items of 130 documents
Repair of a Bacterial Small β-Barrel Toxin Pore Depends on Channel Width
2017
ABSTRACT Membrane repair emerges as an innate defense protecting target cells against bacterial pore-forming toxins. Here, we report the first paradigm of Ca2+-dependent repair following attack by a small β-pore-forming toxin, namely, plasmid-encoded phobalysin of Photobacterium damselae subsp. damselae. In striking contrast, Vibrio cholerae cytolysin, the closest ortholog of phobalysin, subverted repair. Mutational analysis uncovered a role of channel width in toxicity and repair. Thus, the replacement of serine at phobalysin´s presumed channel narrow point with the bulkier tryptophan, the corresponding residue in Vibrio cholerae cytolysin (W318), modulated Ca2+ influx, lysosomal exocytosi…
Falls, Cognitive Function, and Balance Profiles of Singapore Community-Dwelling Elderly Individuals : Key Risk Factors
2017
Objective: This study compared occurrence of falls, cognitive function, and balance profiles across participants in elderly age categories, investigating associations between the 3 aspects in a sample of Singapore’s elderly population. Method: Community-dwelling elderly individuals (N = 385) were randomly recruited and grouped into “young-old (65-74 years),” “medium-old (75-84 years),” and “oldest-old (above 85 years)” groups. The Fallproof Health and Activity questionnaire, adapted Mini-Mental State Examination (MMSE), and Berg Balance Scale (BBS) tests were used to survey information related to falls, cognition, and balance profiles. Results: Findings revealed significant differences in M…
Reframing Teacher Education: Towards the Integration of Phenomenon-Based Curriculum Reform and Organizational Culture
2021
In this article, we report a case study of our experiences of a curriculum reform process based on the principles of phenomenon-based learning in higher education in the context of Finnish teacher education. We explore how democracy and participation were present in the decision making process, highlighting the challenges of promoting the phenomenon-based approach and collaboration. First, we describe the reform’s rationale, then the theoretical framework, methodology and the reform process. Next, we reflect on our experiences through documen tary and interview data. The change process included representative and participative democ racy approaches as well as an aristocratic approach. An in…
Protection of the surviving spouse in French law
2021
While French inheritance law has recently sought to give everyone more freedom to anticipate the transmission of their estate, it still guarantees to the children a reserved portion in his estate. This guarantees the deceased?s children a minimum share in his/her estate. However, the mechanisms protecting this reserve are subject to legal adjustments when spouses wish to organize the protection of the couple?s survivor, either by submitting to a conventional matrimonial regime or by giving themselves gifts that improve the legal succession of the spouse. This ensures a balance between the protection of the spouse and that of the compulsory heirs. Not seeming to be satisfied, several famous …
Optimizing subsurface dripline installation depth with Hydrus 2D/3D to improve irrigation water use efficiency in the central Tunisia
2015
The main objective of the work is to optimize drip installation depth for Eggplant crop irrigated with surface or subsurface drip irrigation systems to improve irrigation Water Use Effeciency (WUE), by means of field measurements and simulations carried out with Hydrus-2D model. Initially, a comparison between simulated Soil Water Contents (SWC) and the corresponding measured in two plots, in which laterals with coextruded emitters are laid on the soil surface (T0) and at 20 cm depth (T20), respectively. In order to choose the best position of the lateral, the results of different simulation run, carried out by choosing a deeper installation (T45) depth. Simulated SWC’s resulted fairly clos…
Mācīšanās no vienaudžiem kā viena no iespējām lasītprasmes apguvē 5-6 gadu veciem bērniem pirmsskolā
2022
Darba tēma: Mācīšanās no vienaudžiem kā viena no iespējām lasītprasmes apguvē 5-6 gadu veciem bērniem pirmsskolā Darba autore: Rasa Celitāne Darba zinātniskā vadītāja: profesore, Dr. pead. Baiba Kaļķe Darba apjoms: 78 lpp. , 5 pielikumi, izmantots 60 literatūras avots Atslēgvārdi: LASĪTPRASME, VIENAUDŽI, 5-6 GADUS VECI BĒRNI. Pētījuma mērķis: izzināt, kā vienaudži var palīdzēt apgūt lasītprasmi 5-6 gadus veciem bērniem pirmsskolā. Pētījuma mērķis ir analizēt un pētīt kā vienaudži palīdz apgūt lasītprasmi.Izvirzītā mērķa sasniegšanai tika analizēta un pētīta teorētiskā literatūra par lasītprasmi un nosacījumiem tās apguvē. Papildus tika pētītas arī 5-6 gadus vecu bērnu psiholoģiskās un fizio…
Numerical Taxonomy of Vibrionaceae Isolated from Cultured Amberjack ( Seriola dumerili ) and Surrounding Water
2003
A numerical taxonomic study was performed on 148 isolates of Gram-negative, heterotrophic, facultative anaerobic bacteria isolated from amberjack (Seriola dumerili) and its surrounding culture water. The study included 30 type and reference strains belonging to genera Vibrio, Listonella, and Photobacterium. The strains were characterized by 109 morphological, biochemical, physiological, and nutritional tests. Cluster analysis of similarity matrices obtained with S(SM) and S(J) coefficients was carried out. UPGMA (unweighted pair group mathematical average) analysis defined 11 phena at S(SM) values > or = 86%. Nine phena were identified as Vibrio alginolyticus, V. fischeri, V. harveyi, V. ca…
Inflation and optimal monetary policy in a model with firm heterogeneity and Bertrand competition
2018
Abstract We study the joint implications of heterogeneity of total factor productivity and strategic price interactions between firms on the dynamics of inflation and the design of optimal monetary policy. In this setting, more productive firms respond less to shocks affecting their marginal costs than less productive firms. As a consequence, economies with a larger proportion of highly productive firms face a flatter Phillips curve. Moreover, when these two features concur, the Ramsey problem gives rise to an optimal non-zero long run inflation that amplifies the differences in relative prices between more efficient and less efficient firms, thus increasing the market share of the former. …
Chromosome-Encoded Hemolysin, Phospholipase, and Collagenase in Plasmidless Isolates of Photobacterium damselae subsp. damselae Contribute to Virulen…
2017
ABSTRACT Photobacterium damselae subsp. damselae is a pathogen of marine animals, including fish of importance in aquaculture. The virulence plasmid pPHDD1, characteristic of highly hemolytic isolates, encodes the hemolysins damselysin (Dly) and phobalysin (PhlyP). Strains lacking pPHDD1 constitute the vast majority of the isolates from fish outbreaks, but genetic studies to identify virulence factors in plasmidless strains are scarce. Here, we show that the chromosome I-encoded hemolysin PhlyC plays roles in virulence and cell toxicity in pPHDD1-negative isolates of this pathogen. By combining the analyses of whole genomes and of gene deletion mutants, we identified two hitherto uncharacte…
Recensione a G. Burgio, Adolescenza e violenza. Il bullismo omofobico come formazione alla maschilità, Milano-Udine, Mimesis, 2012, pp. 250
2015
Recensione a G. Burgio, Adolescenza e violenza. Il bullismo omofobico come formazione alla maschilità, Milano-Udine, Mimesis, 2012, pp. 250