Search results for "MST"
showing 10 items of 363 documents
Metabolism of [3-14C]coumarin to polar and covalently bound products by hepatic microsomes from the rat, Syrian hamster, gerbil and humans.
1992
The metabolism of 0.19 and 2.0 mM-[3-14C]coumarin to polar products and covalently bound metabolites has been studied with hepatic microsomes from the rat, Syrian hamster, Mongolian gerbil and humans. [3-14C]Coumarin was metabolized by liver microsomes from all species to a number of polar products and to metabolite(s) that became covalently bound to microsomal proteins. The polar products included 3-, 5- and 7-hydroxycoumarins, o-hydroxyphenylacetaldehyde and o-hydroxyphenylacetic acid. Coumarin 7-hydroxylation was observed in all species except the rat. With 0.19 mM-[3-14C]coumarin, 7-hydroxycoumarin was the major metabolite in human liver microsomes, whereas in the other species with 0.1…
Evidence of a preprogrammed deactivation of the hamstring muscles for triggering rapid changes of posture in humans
1997
Normal subjects were asked to make rapid flexions of the legs from a stationary initial standing posture in a self-paced mode. Because this movement implicates a rapid change in posture, questions were asked about the type of central command which must include the rupture of the erect posture and the accomplishment of the goal directed movement. Movements of the different segments of the body were recorded and analyzed using the optoelectronic ELITE system. Electromyographic (EMG) activities of 8 muscles of the lower limb on one side were recorded, rectified and integrated. The time relationships of the different EMG signals (activation or deactivation) were analyzed with respect to selecte…
Prevalence and clinical relevance of thyroid stimulating hormone receptor-blocking antibodies in autoimmune thyroid disease
2017
Summary The prevalence and clinical relevance of thyroid stimulating hormone (TSH) receptor (TSHR) blocking antibodies (TBAb) in patients with autoimmune thyroid disease (AITD) was investigated. Serum TBAb were measured with a reporter gene bioassay using Chinese hamster ovary cells. Blocking activity was defined as percentage inhibition of luciferase expression relative to induction with bovine TSH alone (cut-off 40% inhibition). All samples were measured for TSHR stimulatory antibody (TSAb) and TSHR binding inhibiting immunoglobulins (TBII). A total of 1079 unselected, consecutive patients with AITD and 302 healthy controls were included. All unselected controls were negative for TBAb and…
Effects of Combined Strength and Sprint Training on Lean Mass, Strength, Power and Sprint Performance in Masters Road Cyclists
2017
Del Vecchio, L, Stanton, R, Reaburn, P, Macgregor, C, Meerkin, J, Villegas, J, and Korhonen, MT. Effects of combined strength and sprint training on lean mass, strength, power, and sprint performance in masters road cyclists. J Strength Cond Res 33(1): 66-79, 2019-Strength and sprint-training exercises are integral part of training in many younger endurance cyclists to improve cycling efficiency and sprinting ability. This study was undertaken to examine whether muscle and performance characteristics could be improved in endurance-trained masters cyclist by adding strength and sprint-training stimuli into their training regimen. Twenty-five masters road cyclists were assigned to a combined …
Isokinetic strength and anaerobic power of elite, subelite and amateur French soccer players.
2001
Information about the influence of different practice levels on physical characteristics of a large number of soccer players is lacking. Therefore we assessed muscular strength and anaerobic power of elite, subelite and amateur soccer players to clarify what parameters distinguish the top players from the less successful. We tested 95 soccer players from the French first division (elite), second division (subelite), and amateurs and determined the isokinetic strength of the knee extensor and flexor muscles at angular velocities from -120 degrees x s(-1) to 300 degrees x s(-1). Vertical jump, 10 m sprint, 30 m sprint and maximum ball speed during shooting were also measured. The elite player…
Neurophysiological insights on flexibility improvements through motor imagery
2017
International audience; The efficacy of motor imagery (MI) practice to facilitate muscle stretching remains controversial and the underlying neurophysiological mechanisms unexplored. We evaluated the effects of MI practice during a sit-and reach task. Healthy participants were randomly assigned to a MI practice (n = 15) or Control (n = 15) group and completed 2 blocks of 5 sit-and-reach trials. During the first block (B1), participants performed 5 maximal stretching trials of 10s. During the second block (B2), trials were divided into two consecutive parts: i) reproducing the maximum performance of B1 (10s, B2 part 1), and ii) attempting to outperform the maximum performance of B1 (10s, B2 …
Region-dependent hamstrings activity in Nordic hamstring exercise and stiff-leg deadlift defined with high-density electromyography
2018
Recent studies suggest region-specific metabolic activity in hamstring muscles during injury prevention exercises, but the neural representation of this phenomenon is unknown. The aim of this study was to examine whether regional differences are evident in the activity of biceps femoris long head (BFlh) and semitendinosus (ST) muscles during two common injury prevention exercises. Twelve male participants without a history of hamstring injury performed the Nordic hamstring exercise (NHE) and stiff-leg deadlift (SDL) while BFlh and ST activities were recorded with high-density electromyography (HD-EMG). Normalized activity was calculated from the distal, middle, and proximal regions in the e…
Exercise with TENS does not augment gains in balance and strength for dancers
2020
Abstract Electrical stimulation modulates sensory feedback and improves motor performance, at least for individuals with compromised sensorimotor function. The purpose of this study was to determine the effectiveness of a 4-wk intervention with transcutaneous electrical nerve stimulation (TENS) at improving strength and balance in dancers. Nineteen dancers completed a timed, single-leg balance test, the Y-balance test, and contractions with the hip flexor and knee extensor muscles to assess maximal strength and force steadiness. They completed 4-wks of moderate-intensity bodyweight exercises (3x/wk) and were pseudo-randomized to either a Treatment or Sham group in a single-blind design. The…
Reliability of knee extension and flexion measurements using the Con-Trex isokinetic dynamometer.
2007
The aim of this study was to evaluate the reliability of isokinetic and isometric assessments of the knee extensor and the flexor muscle function using the Con-Trex isokinetic dynamometer. Thirty healthy subjects (15 males, 15 females) were tested and retested 7 days later for maximal strength (isokinetic peak torque, work, power and angle of peak torque as well as isometric maximal voluntary contraction torque and rate of torque development) and fatigue (per cent loss and linear slope of torque and work across a series of 20 contractions). For both the knee extensor and the flexor muscle groups, all strength data - except angle of peak torque - demonstrated moderate-to-high reliability, wi…
Superimposing hip extension on knee flexion evokes higher activation in biceps femoris than knee flexion alone.
2021
Hamstring muscle function during knee flexion has been linked to hamstring injury and performance. However, it is unclear whether knee flexion alone (KF) requires similar hamstring electromyography (EMG) activity pattern to simultaneous hip extension and knee flexion (HE-KF), a combination that occurs in the late swing phase of sprinting. This study examined whether HE-KF maximal voluntary isometric contraction (MVIC) evokes higher (EMG) activity in biceps femoris long head (BFlh) and semitendinosus (ST) than KF alone. Effects of shank rotation angles were also tested. Twenty-one males performed the above-mentioned MVICs while EMG activity was measured along ST and BFlh. Conditions were com…