Search results for "MST"
showing 10 items of 363 documents
CSI 2264: Simultaneous optical and X-ray variability in pre-main sequence stars. I. Time resolved X-ray spectral analysis during optical dips and acc…
2017
Pre-main sequence stars are variable sources. In stars with disks, this variability is related to the morphology of the inner circumstellar region (<0.1 AU) and that of the photosphere and corona, all impossible to be spatially resolved with present day techniques. This has been the main motivation for the Coordinated Synoptic Investigation of NGC 2264. In this paper, we focus on the stars with disks. We analyze the X-ray spectral properties extracted during optical bursts and dips in order to unveil the nature of these phenomena. We analyze simultaneous CoRoT and Chandra/ACIS-I observations to search for coherent optical and X-ray flux variability in stars with disks. Then, stars are an…
Ex-ante and ex-post measurement of equality of opportunity in health: a normative decomposition.
2011
This paper proposes and discusses two different approaches to the definition of inequality in health: the ex-ante and the ex-post approach. It proposes strategies for measuring inequality of opportunity in health based on the path-independent Atkinson equality index. The proposed methodology is illustrated using data from the British Household Panel Survey; the results suggest that in the period 2000–2005, at least one-third of the observed health equalities in the UK were equalities of opportunity.
Zvaigžņotā Debess: 2010/11, Ziema (210)
2010
Contents: “ZVAIGŅOTĀ DEBESS” FORTY YEARS AGO: Bursting Stars. J. Francman (abridged). Geodesists Help Renew the Spire of St. Peter’s Church. J. Klētnieks (abridged). DEVELOPMENTS in SCIENCE: The Solar Neutrino Problem. O. Smirnova. NEWS: At Last the Planet at the Star β Pictoris Is Imaged. A. Alksnis, Z. Alksne. SPACE RESEARCH and EXPLORATION: The Trail of an Asteroid Reveals a Recent Collision. A. Alksnis. INTERNATIONAL YEAR of ASTRONOMY 2009: International Year of Astronomy 2009 in Philately. The Rest of the World except Series EUROPA (concluded). J. Limansky. ACADEMIC STAFF of the UNIVERSITY of LATVIA: Assistant Professor in Physics Ojārs Šmits (24.04.1930.-14.03.1993.) of the Latvian Un…
Les modes d'habitat à l'âge du Bronze en France
2018
The many discoveries made in preventive archaeology have drawn the picture of a highly anthropogenic landscape in Bronze Age France. Timber post buildings are the most common type of dwellings however other types of construction (sills, mudbrick, …) that have lighter foundations and are more susceptible to erosion are considered less common due to the inherent problems of identification. Small dwellings from 25 to 40 m2 with a quadrangular 1 to 3 aisled plan and built to house a nuclear family are the most common,. Other types of buildings differ from this standardised plan such as the long rectangular dwellings in Alsace dating to the Early Bronze Age (type Eching) or the Early Bronze Age …
ALMA spectral survey of Supernova 1987A – molecular inventory, chemistry, dynamics and explosive nucleosynthesis
2017
We report the first molecular line survey of Supernova 1987A in the millimetre wavelength range. In the ALMA 210--300 and 340--360 GHz spectra, we detected cold (20--170 K) CO, 28SiO, HCO+ and SO, with weaker lines of 29SiO from ejecta. This is the first identification of HCO+ and SO in a young supernova remnant. We find a dip in the J=6--5 and 5--4 SiO line profiles, suggesting that the ejecta morphology is likely elongated. The difference of the CO and SiO line profiles is consistent with hydrodynamic simulations, which show that Rayleigh-Taylor instabilities cause mixing of gas, with heavier elements much more disturbed, making more elongated structure. We obtained isotopologue ratios of…
Arsenic-induced DNA hypomethylation affects chromosomal instability in mammalian cells
2004
Early genetic instability induced in dividing V79-Cl3 Chinese hamster cells by inorganic arsenic, as demonstrated in our previous investigation, was evidenced by aneuploidy and nuclear abnormalities, but not by chromosomal rearrangements. Here we report the results of cytogenetic and morphological analyses performed on the progeny of cells dividing at the end of sodium arsenite treatment after they had been expanded through 120 generations (ASO cells) and then cloned. The acquired genetic instability persisted and was increased by highly unstable chromosomal rearrangements, namely dicentric chromosomes and telomeric associations, which were not seen following acute exposure. A peculiar find…
Stable expression of rat cytochrome P450IA2 cDNA and hydroxylation of 17β-estradiol and 2-aminofluorene in V79 Chinese hamster cells
1991
In continuation of our work toward the establishment of a working cell bank for metabolic and toxicological studies, V79 Chinese hamster cells were genetically engineered for stable expression of rat cytochrome P450IA2. Full-length cDNA encoding rat P450IA2 was obtained by searching a cDNA library made from Aroclor 1254-induced rat liver mRNA and by joining a small 5'-end fragment to a fragment containing the rest of the cDNA. The sequence of the cDNA was confirmed by DNA sequencing and comparison to a previously published cDNA sequence. The reconstructed full-length cDNA was inserted into a simian virus 40 early promoter-containing eukaryotic expression vector and cotransferred with the ne…
Pixel-to-pixel correlation between images of absolute ATP concentrations and blood flow in tumours
1992
Iodo(14C-)antipyrine autoradiography and imaging bioluminescence have been combined to obtain pixel-to-pixel correlations between absolute values for local blood flow and ATP concentrations at a microscopical level within designated areas in hamster melanomas. Positive pixel-to-pixel correlations were obtained in 4 of 6 tumours. Both flow and ATP values were less in mostly necrotic than in mostly viable tumour regions. The data provide evidence for the energetic state of cancer cells being strongly influenced by the efficiency of tumour microcirculation in several but not in all malignancies investigated. Images Figure 1
Overexpression of Ogg1 in mammalian cells: effects on induced and spontaneous oxidative DNA damage and mutagenesis
1999
Chinese hamster ovary cell lines (AA8 and AS52) were stably transfected to overexpress hOgg1 protein, the human DNA repair glycosylase for 7,8-dihydro-8-oxoguanine (8-oxoG). In the transfectants, the repair rate of 8-oxoG residues induced by either potassium bromate or the photosensitizer [R]-1-[(10-chloro-4-oxo-3-phenyl-4H-benzo[a]quinolizin-1-yl)-carbo nyl ]-2-pyrrolidinemethanolplus light was up to 3-fold more rapid than in the parental cells. However, the improved repair had little effect on the mutagenicity of potassium bromate in the guanine phosphoribosyl transferase (gpt) locus of the OGG1-transfected AS52 cells. The steady-state (background) levels of DNA base modifications sensiti…
Detoxification of optically active bay- and fjord-region polycyclic aromatic hydrocarbon dihydrodiol epoxides by human glutathione transferase P1-1 e…
1998
Dihydrodiol epoxides (DEs) are important carcinogenic metabolites of polycyclic aromatic hydrocarbons (PAHs). The metabolic formation of four stereoisomeric DEs (a pair of optically active diastereomers termed as syn- and anti-form) is possible. Glutathione tranferases (GSTs) have been demonstrated to catalyze the detoxification of DEs. Purified GSTs display remarkable differences in catalytic efficiencies towards bay- and fjord-region DEs along with a high degree of regio- and stereoselectivity. Here we determined to which extent heterologously expressed human GSTP1-1, a major GST isoform in lung, affects the mutagenicity of stereoisomeric bay-region DEs of benzo[a]pyrene in Chinese hamste…