Search results for "MTRR"

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Methionine synthase reductase (MTRR) A66G polymorphism is not related to plasma homocysteine concentration and the risk for vascular disease.

2009

Epidemiological evidence has revealed that hyperhomocysteinemia increases the risk for vascular disease. Methionine Synthase Reductase (MTRR) is one of several key enzymes in the homocysteine metabolic pathway and its mutant forms have been implicated in abnormal homocysteine accumulation. In this study, we determined total plasma homocysteine levels and MTRR A66G polymorphism in 114 patients with vascular disease: 58 patients with deep-vein thrombosis, 56 patients with arterial thrombosis, and 95 healthy subjects from the Sicilian population. Our data confirmed that, as already reported, moderately elevated t-Hcy levels are correlated with an increased risk of vascular disease. In our stud…

AdultMalemedicine.medical_specialtyHyperhomocysteinemiaMethyltransferaseHomocysteineClinical BiochemistryPopulationMethionine synthase reductase homocysteinePolymorphism Single NucleotidePathology and Forensic Medicinechemistry.chemical_compoundInternal medicineMedicineHumansGenetic Predisposition to DiseaseVascular DiseaseseducationMolecular BiologyHomocysteineAgededucation.field_of_studybiologybusiness.industryVascular disease(Methionine synthase) reductaseMiddle Agedmedicine.diseaseMTRRFerredoxin-NADP ReductaseVenous thrombosisEndocrinologyBiochemistrychemistryCase-Control Studiesbiology.proteinFemalebusinessExperimental and molecular pathology
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