Search results for "MVA"
showing 10 items of 89 documents
Effects of fluvastatin slow-release (XL 80 mg) versus simvastatin (20 mg) on the lipid triad in patients with type 2 diabetes.
2005
The lipid triad is the association of small, dense (sd) low-density lipoprotein (LDL), low high-density lipoprotein (HDL), and hypertriglyceridemia, all of which play a role in coronary artery disease in patients with type 2 diabetes. Although statins have demonstrated clear positive effects on cardiovascular morbidity/mortality in patients with diabetes and on single components of the lipid triad, it remains controversial whether they affect all components of the triad in these patients. Therefore, we performed a single-center, parallel-group, prospective, randomized, open-label, blinded-endpoint (PROBE)-type comparison of fluvastatin extended-release (XL) 80 mg (n=48) and simvastatin 20 m…
Structural Relationships between Floating and Deposited Monolayers of Docosanoic Acid
1991
Floating docosanoic acid (behenic acid) monolayers in the SmI and SmH phase were deposited with the Langmuir-Blodgett technique onto thin polymethylmethacrylate (PMMA) and Formvar substrates and investigated by electron diffraction. The molecular packing of the monolayers on the substrates vary from those on the water surface and are different for different substrates. On PMMA four phases (H, SmB, SmI, SmL) have been identified, depending on the deposition conditions. While SmB and SmI are known for docosanoic acid on the water surface, H and SmL have only been unequivocally observed in other substances or on other subphases. The monolayer structure on Formvar was identical under all deposi…
Analysis of measurements of stopping powers of formvar, polyimide, polysulfone, and vyns for 3.6 to 10.5 MeV7Li ions
2002
The stopping powers of formvar, polysulfone, polyimide, and vyns for 7Li projectiles have been measured with the transmission technique and thin foil targets. The experimental data have been analyzed in terms of modified Bethe–Bloch theory to extract characteristic values of the mean excitation energy and Barkas effect parameter, as well as to study the effects of including a single effective charge parameter. Results of this investigation are in general supportive of the outcomes of earlier similar studies with protons and α-particles traversing the same target materials in the sense that previously reported trends in projectile-dependent behavior of values of mean excitation energy and Ba…
Unvolvement of calcium signaling and MAP kinases in lipid taste perception
2013
In this work, we demonstrate that stromal interaction molecule 1 (STIM1), a sensor of Ca2+ depletion in the endoplasmic reticulum, mediates fatty acid–induced Ca2+ signaling in the mouse tongue and fat preference. We showed that linoleic acid (LA) induced the production of arachidonic acid (AA) and lysophosphatidylcholine (Lyso-PC) by activating multiple phospholipase A2 isoforms via CD36. This activation triggered Ca2+ influx in lingual CD36-positive taste bud cells (TBCs) purified from mouse CVP. LA also induced the production of Ca2+ influx factor (CIF). STIM1 was found to regulate LA-induced CIF production and the opening of store-operated Ca2+ (SOC) channels. Furthermore, CD36-positive…
En studie av de faktorer som bidrar til effekter ved PDAbruk i norsk hjemmesykepleie
2006
Masteroppgave i informasjonssystemer 2006 - Høgskolen i Agder, Kristiansand Helsesektoren i Norge er en belastet sektor som skal betjene et økende antall hjemmeboende klienter og bistå dem med helsetjenester og hjelp til daglige gjøremål. Etaten sliter med lav bemanning og begrensede midler. Dette har bidratt til at man har fått fremvekst av moderniseringstiltak i sektoren. Moderniseringen kan ta flere former og denne oppgaven ser i hovedsak på bruk av PDAer i norsk hjemmesykepleie. PDAer er små håndholdte PC-er som kan gi mobil tilgang til informasjon som tidligere var papirbasert og utilgjengelig for pleiepersonell ute på mobile oppdrag. Det er en rekke potensielle effekter ved slike PDA-…
Augsti funkcionālu poliolu sintēze no epoksidētas rapšu eļļas cieto poliuretānu putu izstrādāšanai
2015
Darbā veikts literatūras apskats par dažādu veidu polioliem, to iegūšanas reakcijām un to raksturlielumu analīzes metodēm. Tika apskatīti poliētera, poliestera un no dabasvielām iegūtie polioli. Izpētīta rapšu eļļas epoksidēšanās reakcijas kinētika 55, 60, 65 oC. No rapšu eļļas tika iegūts epoksidācijas produkts, kuru modificēja ar dietanolamīnu, trietanolamīnu un dietilēnglikolu. Iegūtajiem polioliem tika noteikti to raksturlielumi un tika veikta to salīdzināšana. Iegūtie polioli papildus tika analizēti ar Furjē transformācijas infrasarkanās spektraskopijas (FTIR) metodi un gēla caurlaidības hromatogrāfiju (GPC). No iegūtajiem polioliem tika iegūti cieto putu poliuretānu materiāli, kuriem …
Daugavpils tramvaju satiksmes izveidošanās un darbības sākums (1946-1949)
2019
Bakalaura darbs veltīts “Daugavpils tramvaju satiksmes izveidošanai un darbības sākumam (1946-1949)”, tiek pētīta viena no Latvijas Padomju Sociālistiskās Republikas rūpniecības un sabiedriskā transporta iestādēm. Bakalaura darbs hronoloģiski aptver laika posmu no 1946.-1949. gadam. Bakalaura darba mērķis ir izpētīt Daugavpils tramvaju satiksmes izveidošanas un darbības sākumu un ar to saistītās problēmas. Darba beigās izdarīti secinājumi, ka Daugavpils tramvaja ieviešanas problemātika un Daugavpils pēckara stāvoklis kalpoja ne tikai pilsētas infrastruktūras uzlabošanai, bet arī padomju varas pozitīvā tēla atspoguļojumam, izmantojot propagandu presē un tautas iesaisti tramvaja celtniecībā u…
Increased thrombin generation and complement activation in patients with type IIA hyperlipoproteinemia: effects of simvastatin treatment
1997
Abstract The aim of this study was to demonstrate the existence of increased thrombin generation and complement activation in patients with type IIa primary hyperlipoproteinemia, but no signs of atherosclerotic vascular disease and to assess the effects of simvastatin treatment in these patients. We studied 40 patients with type IIa primary hyperlipoproteinemia and 40 healthy subjects matched for sex, age, body mass index, and smoking status. The study was divided into two phases. In the first phase, a cross-sectional comparison of lipid and hemostatic patterns was performed between patients and controls. In the second phase, we assessed the effect of a persistent reduction in cholesterol s…
Lipid-Altering Efficacy of Ezetimibe/Simvastatin 10/20 mg Compared to Rosuvastatin 10 mg in High-Risk Patients with and without Type 2 Diabetes Melli…
2010
SUMMARY Aims: This post hoc analysis compared the effects of switching to ezetimibe/simvastatin 10/20 mg (EZE/SIMVA) or rosuvastatin 10 mg (ROSUVA) in uncontrolled high-risk hypercholesterolemic patients with/without type 2 diabetes mellitus (T2DM) despite statin monotherapy. Methods: Patients (n = 618) at high risk for coronary vascular disease with elevated LDL-C ≥100 and ≤190 mg/dL despite use of statins were randomized 1:1 to double-blind EZE/SIMVA 10/20 mg or ROSUVA 10 mg for 6 weeks. Patients were classified as having T2DM based on ≥1 of the following: diagnosis of T2DM, antidiabetic medication, or FPG ≥126 mg/dL. This analysis evaluated percent changes from baseline in lipids among p…
Rietumvalstu sankciju ietekme uz Krievijas ārpolitiku pēc Krimas aneksijas
2018
Darba nosaukums: Rietumvalstu sankciju ietekme uz Krievijas ārpolitiku pēc Krimas aneksijas. Darba mērķis: Izpētīt Rietumvalstu piemēroto sankciju ietekmi uz Krievijas ārpolitiskajām darbībām. Izpētes jautājums: Kā ir mainījusies Krievijas ārpolitika pēc Rietumvalstu sankciju ieviešanas attiecībā uz Krieviju pēc Krimas aneksijas? Darba struktūra: Teorētiskā daļa: analizēt spēka diplomātiju kā vienu no ārpolitikas stratēģijām, tās koncepciju, dažādās izpratnes, panākuma faktorus un kā tiek definēts tās panākums. Raksturot ekonomiskās sankcijas, to trūkumus, ietekmes veidus un ietekmes jomas. Empīriskā daļa: Veikt Krievijas ārpolitikas mērķu izpēti Ukrainas krīzes kontekstā, balstoties uz iep…