Search results for "Maintena"

showing 4 items of 394 documents

Face-work in intimate public conversation : men and women's talk in Ricki Lake show

2000

talk showface threatening actpolitenessfacegenderembarrassmentface-maintenance
researchProduct

VERNACULAR ARCHITECTURE IN INSULAR ITALY: HERITAGE TO PRESERVE AND VALUE

2021

The Mediterranean civilisation, in its millenary history, has also expressed itself through particular artefacts that have strongly characterised the territory. Knowledge of the artefacts that "qualify" a territory, both in historical and material terms, is a necessary prerequisite for tackling the planning and management problems relating to their protection and conservation. The architecture of the "vernacular" is linked to domestic life, customs, the "dialects" of places and the essence of the Genius Loci. The building heritage of the islands surrounding Sicily features special building techniques and systems that exploit natural resources to generate original artefacts and extremely fun…

technological architecture heritage vernacular architecture materials maintenanceSettore ICAR/12 - Tecnologia Dell'Architettura
researchProduct

The prolyl-isomerase PIN1 is essential for nuclear Lamin-B structure and function and protects heterochromatin under mechanical stress.

2021

Summary: Chromatin organization plays a crucial role in tissue homeostasis. Heterochromatin relaxation and consequent unscheduled mobilization of transposable elements (TEs) are emerging as key contributors of aging and aging-related pathologies, including Alzheimer’s disease (AD) and cancer. However, the mechanisms governing heterochromatin maintenance or its relaxation in pathological conditions remain poorly understood. Here we show that PIN1, the only phosphorylation-specific cis/trans prolyl isomerase, whose loss is associated with premature aging and AD, is essential to preserve heterochromatin. We demonstrate that this PIN1 function is conserved from Drosophila to humans and prevents…

transposonsNeocortexMiceHeterochromatinProlyl isomeraseDrosophila ProteinsBiology (General)PhosphorylationRNA Small InterferingTissue homeostasisCells CulturedSettore ING-INF/05 - Sistemi Di Elaborazione Delle InformazioniNeuronsLamin Type BChemistryHP1phosphorylationneurodegenerationnuclear envelopePeptidylprolyl IsomeraseCell biologyDrosophila heterochromatin HP1 Lamin mechanical stress neurodegeneration nuclear envelope phosphorylation PIN1 transposonsNuclear laminaDrosophilaRNA InterferencePremature agingQH301-705.5HeterochromatinNuclear EnvelopeDrosophila; heterochromatin; HP1; Lamin; mechanical stress; neurodegeneration; nuclear envelope; phosphorylation; PIN1; transposonsSettore BIO/11 - Biologia MolecolareSettore MED/08 - Anatomia PatologicaGeneral Biochemistry Genetics and Molecular BiologyPIN1Alzheimer DiseaseSettore MED/05 - Patologia ClinicaAnimalsHumansHeterochromatin maintenancemechanical stressheterochromatinmechanical streMice Inbred C57BLNIMA-Interacting Peptidylprolyl IsomeraseChromobox Protein Homolog 5DNA Transposable ElementsHeterochromatin protein 1Stress MechanicalLaminLaminCell reports
researchProduct

Visual working memory resource allocation mechanism in consolidation and maintenance phase

2018

Visual working memory (VWM) is a system for actively maintaining visual information to meet the needs of an ongoing task. It allows individuals to store visual input information from a complex outside environment and provides storage space as an information buffer platform to help integrate information into a continuous visual experience. This research examined the consolidation and maintenance phase of the VWM resource allocation mechanism. Four aspects of this issue were investigated. First, resource allocation in VWM consolidation was investigated for different materials, and it was determined whether VWM resources were allocated in a serial manner for orientation materials but in a limi…

visual working memoryresource allocationmuistitwo-phasenäkömuistityömuistimuistiresurssitconsolidationmaintenance
researchProduct