Search results for "Mantle"

showing 10 items of 322 documents

Geochemical evolution of rift magmas by progressive tapping of a stratified mantle source beneath the Ross Sea Rift, Northern Victoria Land, Antarcti…

1995

Abstract Source compositions of Neogene-Quaternary volcanic rocks from the McMurdo Volcanic Group of the Ross Sea Rift in Northern Victoria Land, Antarctica are constrained by NdSrPb isotopes and trace element ratios in near-primary basalts. The rocks erupted along the western rift margin (Victoria Land Basin) and the western rift shoulder (Transantarctic Mountains). Near-primary basalts show no evidence of crustal contamination, suggesting that their initial NdSrPb isotopes reflect the composition of their mantle sources. The initial isotope ratios of near-primary basalts range from about 87 Sr 86 Sr = 0.70281 to 0.70504 and 143 Nd 144 Nd = 0.51269 to 0.51291 (ϵNd(t) = 1.3–5.5). The 20…

Basaltgeographygeography.geographical_feature_categoryRiftGeochemistryMantle (geology)Mantle plumeVolcanic rockGeophysicsVolcanoSpace and Planetary ScienceGeochemistry and PetrologyLithosphereMagmatismEarth and Planetary Sciences (miscellaneous)Geology
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Large- and Fine-Scale Geochemical Variations Along the Andean Arc of Northern Chile (17.5°– 22°S)

1994

Geochemical data from 37 volcanic centres from the active volcanic front in the Central Andes between 17.5° and 22°S of northern Chile provide constraints on crustal contributions to arc magma genesis in that region. Crustal thickness, distance from the trench, height above the seismically active subduction zone, and sediment supply to the trench are all constant along this segment of the arc. The only significant variable along the current arc segment is in mean crustal age (Palaeozoic in the south to Proterozoic in the north). In addition, the crustal thickness has varied through time from around 40 km in the Lower Miocene to about 70 km today. Variations along the N-S chain of the volcan…

Basaltgeographygeography.geographical_feature_categorybiologyRhyodaciteSubductionAndesitesGeochemistrybiology.organism_classificationMantle (geology)Tectonic upliftBasaltic andesiteVolcanoGeology
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Investigation of the He solubility in H2O-CO2 bearing silicate liquids at moderate pressure: a new experimental method

2000

We have designed the first available experimental method capable to investigate the solubility of inert gases in H2O–CO2 bearing silicate melts in a large range of pressures. The method overcomes the difficulties imposed by the physical state of volatiles at room conditions. Experiments were done by using an internally heated pressure vessel, where sealed capsules containing the sample are introduced. The peculiarity of the method consists in the capability of loading, in accurately known proportions (even lower than ppm), volatiles in a gaseous state at room conditions. Gas is loaded as a weighed amount of a gas-bearing glass, which was previously prepared by using the same gas as a pressu…

BasaltsolubilityMineralogyNoble gaschemistry.chemical_elementheliumSilicatePressure vesselMantle (geology)chemistry.chemical_compoundpressureGeophysicschemistryChemical engineeringexperimental studiessilicate meltsSpace and Planetary ScienceGeochemistry and Petrologyexperimental studies; helium; pressure; silicate melts; solubilityEarth and Planetary Sciences (miscellaneous)SolubilityDissolutionGeologyHelium
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Sources, degassing, and contamination of CO2, H2O, He, Ne, and Ar in basaltic glasses from Kolbeinsey Ridge, North Atlantic

2005

Abstract New volatile data (CO2, H2O, He, Ne, and Ar) are presented for 24 submarine basaltic glasses from the Kolbeinsey Ridge, Tjornes Fracture Zone and Mohns Ridge, North Atlantic. Low CO2 and He contents indicate that magmas were strongly outgassed with the extent of degassing increasing toward the south, as expected from shallower ridge depths. Ne and Ar are significantly more abundant in the southernmost glasses than predicted for degassed melt. The strong atmospheric isotopic signal associated with this excess Ne and Ar suggests syn- or posteruptive contamination by air. Degassing, by itself, cannot generate the large variations in δ13C values of dissolved CO2 or coupled CO2-Ar varia…

Basaltδ13CGeochemistry and PetrologyHomogeneousGeochemistryFracture zoneContaminationGeologyMantle (geology)Geochimica et Cosmochimica Acta
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Final Results of a Phase I/II Trial of the Combination Bendamustine and Rituximab With Temsirolimus (BeRT) in Relapsed Mantle Cell Lymphoma and Folli…

2020

Abstract. In this phase I/II study, we explored the combination of Temsirolimus with Bendamustine and Rituximab (BeRT) in patients with relapsed or refractory (r/r) follicular lymphoma (FL) or mantle cell lymphoma (MCL). Patients with 1 to 3 previous therapies received Bendamustine (90 mg/m2, day 1 + 2) and Rituximab (375 mg/m2, day 1) with Temsirolimus in doses from 25 to 75 mg in phase I and 50 mg Temsirolimus in phase II, added on day 1, 8, 15 of a 28 days cycle. The primary endpoint of the phase II was ORR at the end of treatment. Overall, 39 (29 MCL, 10 FL) patients were included. Median age was 71 years and median pretreatment number was 2. Grade 3/4 non-hematologic adverse events wer…

Bendamustinemedicine.medical_specialtyCancer ResearchLeukopeniabusiness.industrylcsh:RC633-647.5Follicular lymphomaHematologylcsh:Diseases of the blood and blood-forming organsNeutropeniamedicine.diseaseGastroenterology002TemsirolimusArticleRegimenInternal medicinehemic and lymphatic diseasesmedicineMantle cell lymphomaRituximabmedicine.symptombusinessmedicine.drugHemaSphere
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Variability of shell repair in the Manila clam Ruditapes philippinarum affected by the Brown Ring Disease: A microstructural and biochemical study

2011

11 pages; International audience; For more than two decades, the Manila clam Ruditapes philippinarum has been regularly affected by Brown Ring Disease (BRD), an epizootic event caused by the bacterium Vibrio tapetis and characterized by the development of a brown deposit on the inner face of valves. Although BRD infection is often lethal, some clams recover by mineralizing a new repair shell layer, which covers the brown deposit and fully isolates it from living tissues. In order to understand this specific shell repair process, the microstructures of repaired zones were compared to those of shells unaffected by BRD. In addition, the organic matrix associated with unaffected shells and to r…

BiomineralizationEnzyme-Linked Immunosorbent AssayRuditapesInternal layer03 medical and health sciencesHemolymphAnimalsShell repair[SDV.IB.BIO]Life Sciences [q-bio]/Bioengineering/BiomaterialsMantle (mollusc)MicrostructureMolluscaAntibodyEcology Evolution Behavior and SystematicsVibrio030304 developmental biology0303 health sciencesbiologySecretory regime030302 biochemistry & molecular biologyAnatomy[ SDV.IB.BIO ] Life Sciences [q-bio]/Bioengineering/BiomaterialsBivalviabiology.organism_classificationBivalviaCalcifying matrixCell biologyVibrio tapetisPolyclonal antibodiesbiology.proteinElectrophoresis Polyacrylamide GelMolluscBiomineralizationJournal of Invertebrate Pathology
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The shell organic matrix of the crossed lamellar queen conch shell (Strombus gigas)

2014

10 pages; International audience; In molluscs, the shell organic matrix comprises a large set of biomineral-occluded proteins, glycoproteins and polysaccharides that are secreted by the calcifying mantle epithelium, and are supposed to display several functions related to the synthesis of the shell. In the present paper, we have characterized biochemically the shell matrix associated to the crossed-lamellar structure of the giant queen conch Strombus gigas. The acid-soluble (ASM) and acid-insoluble (AIM) matrices represent an extremely minor fraction of the shell. Both are constituted of polydisperse and of few discrete proteins among which three fractions, obtained by preparative SDS-PAGE …

BiomineralizationPhysiologyGastropodaCarbohydratesMineralogyMannose010402 general chemistry01 natural sciencesBiochemistryCalcium CarbonateConch03 medical and health sciencesMatrix (mathematics)chemistry.chemical_compoundAnimal ShellsShellAnimalsMonosaccharide[SDV.IB.BIO]Life Sciences [q-bio]/Bioengineering/BiomaterialsMantle (mollusc)Molecular BiologyGlycoproteins030304 developmental biologychemistry.chemical_classification0303 health sciencesbiologyProteinsCrossed-lamellarImmunogold labelling[ SDV.IB.BIO ] Life Sciences [q-bio]/Bioengineering/Biomaterialsbiology.organism_classificationCalcifying matrix0104 chemical sciencesCrystallographyStrombuschemistryMolluscCrystallizationGlycoproteinComparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology
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Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas

2007

AbstractIntegrative genomic and gene-expression analyses have identified amplified oncogenes in B-cell non-Hodgkin lymphoma (B-NHL), but the capability of such technologies to localize tumor suppressor genes within homozygous deletions remains unexplored. Array-based comparative genomic hybridization (CGH) and gene-expression microarray analysis of 48 cell lines derived from patients with different B-NHLs delineated 20 homozygous deletions at 7 chromosome areas, all of which contained tumor suppressor gene targets. Further investigation revealed that only a fraction of primary biopsies presented inactivation of these genes by point mutation or intragenic deletion, but instead some of them w…

BiopsyDNA Mutational AnalysisGene DosageVesicular Transport ProteinsApoptosisBiochemistryEpigenesis Geneticimmune system diseaseshemic and lymphatic diseasesChromosomes HumanGenes Tumor SuppressorPromoter Regions GeneticSorting NexinsOligonucleotide Array Sequence AnalysisSequence DeletionBcl-2-Like Protein 11HomozygoteChromosome MappingNuclear ProteinsNucleic Acid HybridizationRNA-Binding ProteinsHematologyDNA NeoplasmBCL10Gene Expression Regulation Neoplasticmedicine.anatomical_structureProto-Oncogene Proteins c-bcl-2DNA methylationLymphoma B-CellTumor suppressor geneImmunologyBiologyGene dosageCell Line TumorProto-Oncogene ProteinsmedicineCyclin-Dependent Kinase Inhibitor p18HumansPoint MutationGene SilencingB cellAdaptor Proteins Signal TransducingHomeodomain ProteinsMembrane ProteinsCell BiologyDNA Methylationmedicine.diseaseMolecular biologyLymphomaCancer researchMantle cell lymphomaApoptosis Regulatory ProteinsCarrier ProteinsDiffuse large B-cell lymphomaTranscription Factors
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Origin of potassic postcollisional volcanic rocks in young, shallow, blueschist-rich lithosphere

2020

Unusually high Th/La in K-rich orogenic rocks may indicate shallow blueschist-rich sources in accretionary settings.

BlueschistgeographyMultidisciplinarygeography.geographical_feature_category010504 meteorology & atmospheric sciencesContinental collisionLawsoniteSubductionGeochemistrySciAdv r-articlesGeology010502 geochemistry & geophysics01 natural sciencesMantle (geology)Volcanic rockGeochemistryVolcanoLithosphereResearch ArticlesGeologyResearch Article0105 earth and related environmental sciencesScience Advances
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GEOLOGIA DE LAS MARGENES DE LA PLACA DEL CARIBE: GENERALIDADES EN GUATEMALA, COSTA RICA, LA ESPAÑOLA Y RESULTADOS PRELIMINARES DEL ANALISIS DE UNA TR…

2011

The Caribbean Plate margins are constituted by deformed belts built up since the Cretaceous in acompressional and strike-slip stress field, which allowed overthrusting of the Caribbean crust onto the Pacific,North and South American Plates.The Caribbean borders include Jurassic-Cretaceous ophiolitic units (Great Antilles, Venezuela, Costa Rica,Guatemala, etc.), composed by mantle peridotites, gabbros, volcanic and sedimentary covers, which have beendeformed in at least two ductile penetrative phases and were often metamorphosed in the prehnite-pumpelleyite,green and blue schist, amphibolite, and in places eclogite facies. These units may present part of a subductioncomplex or are an accreti…

Blueschistgeographygeography.geographical_feature_categoryCrustGeneral MedicineMantle (geology)CretaceousVolcanoSouth americanSedimentary rockGeomorphologyCartographyMetamorphic faciesGeology
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