Search results for "Matrix"
showing 10 items of 3205 documents
Persistent episomal transgene expression in liver following delivery of a scaffold/matrix attachment region containing non-viral vector
2008
An ideal gene therapy vector should enable persistent transgene expression without limitations of safety and reproducibility. Here we report the development of a non-viral episomal plasmid DNA (pDNA) vector that appears to fulfil these criteria. This pDNA vector combines a scaffold/matrix attachment region (S/MAR) with a human liver-specific promoter (alpha1-antitrypsin (AAT)) in such a way that long-term expression is enabled in murine liver following hydrodynamic injection. Long-term expression is demonstrated by monitoring the longitudinal luciferase expression profile for up to 6 months by means of in situ bioluminescent imaging. All relevant control pDNA constructs expressing luciferas…
Notice of Violation of IEEE Publication Principles: New Delay-Dependent Exponential $H_{\infty}$ Synchronization for Uncertain Neural Networks With M…
2010
This paper establishes an exponential H infin synchronization method for a class of uncertain master and slave neural networks (MSNNs) with mixed time delays, where the mixed delays comprise different neutral, discrete, and distributed time delays. The polytopic and the norm-bounded uncertainties are separately taken into consideration. An appropriate discretized Lyapunov-Krasovskii functional and some free-weighting matrices are utilized to establish some delay-dependent sufficient conditions for designing delayed state-feedback control as a synchronization law in terms of linear matrix inequalities under less restrictive conditions. The controller guarantees the exponential H infin synchr…
Asynchronously switched control of discrete impulsive switched systems with time delays
2013
This paper is concerned with the stabilization problem for a class of uncertain discrete impulsive switched delay systems under asynchronous switching. The so-called asynchronous switching means that the switches between the candidate controllers and system modes are asynchronous. By using the average dwell time (ADT) approach, sufficient conditions for the existence of an asynchronously switched controller is derived such that the resulting closed-loop system is exponentially stable. The desired controller gains and the admissible switching signals are obtained in terms of a set of matrix inequalities. A numerical example is given to illustrate the effectiveness of the proposed method.
Finite element method for a nonlocal Timoshenko beam model
2014
A finite element method is presented for a nonlocal Timoshenko beam model recently proposed by the authors. The model relies on the key idea that nonlocal effects consist of long-range volume forces and moments exchanged by non-adjacent beam segments, which contribute to the equilibrium of a beam segment along with the classical local stress resultants. The long-range volume forces/moments are linearly depending on the product of the volumes of the interacting beam segments, and their relative motion measured in terms of the pure beam deformation modes, through appropriate attenuation functions governing the spatial decay of nonlocal effects. In this paper, the beam model is reformulated wi…
Signalling molecules and growth factors for tissue engineering of cartilage-what can we learn from the growth plate?
2009
Modern tissue engineering concepts integrate cells, scaffolds, signalling molecules and growth factors. For the purposes of regenerative medicine, fetal development is of great interest because it is widely accepted that regeneration recapitulates in part developmental processes. In tissue engineering of cartilage the growth plate of the long bone represents an interesting, well-organized developmental structure with a spatial distribution of chondrocytes in different proliferation and differentiation stages, embedded in a scaffold of extracellular matrix components. The proliferation and differentiation of these chondrocytes is regulated by various hormonal and paracrine factors. Thus, mem…
Determination of Fungi and Multi-Class Mycotoxins in Camelia sinensis and Herbal Teas and Dietary Exposure Assessment
2020
In this paper, a study of fungal and multi-mycotoxin contamination in 140 Camellia sinensis and 26 herbal teas marketed in Latvia is discussed. The analysis was performed using two-dimensional liquid chromatography with time-of-flight mass spectrometry (2D-LC-TOF-MS) and MALDI-TOF-MS. In total, 87% of the tea samples tested positive for 32 fungal species belonging to 17 genera, with the total enumeration of moulds ranging between 1.00 ×
Evidence for the associated production of a W boson and a top quark in ATLAS at √s = 7 TeV
2012
This Letter presents evidence for the associated production of a W boson and a top quark using 2.05 fb[superscript −1] of pp collision data at √s = 7 TeV accumulated with the ATLAS detector at the LHC. The analysis is based on the selection of the dileptonic final states with events featuring two isolated leptons, electron or muon, with significant transverse missing momentum and at least one jet. An approach based on boosted decision trees has been developed to improve the discrimination of single top-quark Wt events from background. A template fit to the final classifier distributions is performed to determine the cross-section. The result is incompatible with the background-only hypothes…
Factors selection in landslide susceptibility modelling on large scale following the gis matrix method: application to the river Beiro basin (Spain)
2012
A procedure to select the controlling factors connected to the slope instability has been defined. It allowed us to assess the landslide susceptibility in the Rio Beiro basin (about 10 km2) over the northeastern area of the city of Granada (Spain). Field and remote (Google EarthTM) recognition techniques allowed us to generate a landslide inventory consisting in 127 phenomena. To discriminate between stable and unstable conditions, a diagnostic area had been chosen as the one limited to the crown and the toe of the scarp of the landslide. 15 controlling or determining factors have been defined considering topographic, geologic, geomorphologic and pedologic available data. Univariate tests, …
The performance of molybdenum toughened alumina cutting tools in turning a particulate metal matrix composite
2003
In this paper, a study of the tool wear mechanism in turning aluminium alloy reinforced with alumina using molybdenum-toughened alumina tools is presented. Alumina tools with three different amounts (15, 20 and 25 vol.%) of molybdenum were prepared and tested. The wear type was identified and its evolution with cutting time was measured. The results show that the main mechanism of tool wear is abrasion and not heat. The best overall performance was achieved, as far as flank wear is concerned, using the tool with 20 vol.% of molybdenum added. This has been explained using some of the composites intrinsic properties. SEM examination revealed that molybdenum particles are easily torn from the …
Clarkson-McCarthy inequalities with unitary and isometry orbits
2020
Abstract A refinement of a trace inequality of McCarthy establishing the uniform convexity of the Schatten p-classes for p > 2 is proved: if A , B are two n-by-n matrices, then there exists some pair of n-by-n unitary matrices U , V such that U | A + B 2 | p U ⁎ + V | A − B 2 | p V ⁎ ≤ | A | p + | B | p 2 . A similar statement holds for compact Hilbert space operators. Another improvement of McCarthy's inequality is given via the new operator parallelogramm law, | A + B | 2 ⊕ | A − B | 2 = U 0 ( | A | 2 + | B | 2 ) U 0 ⁎ + V 0 ( | A | 2 + | B | 2 ) V 0 ⁎ for some pair of 2n-by-n isometry matrices U 0 , V 0 .