Search results for "Maxim"

showing 10 items of 1236 documents

Acute effects of dynamic stretching on mechanical properties result from both muscle-tendon stretching and muscle warm-up

2019

We investigated the acute effects of dynamic stretching on mechanical properties of plantar flexor muscles and tested the hypothesis that it would result from an interaction between muscle-tendon stretching and muscle warm-up. To test the stretching effect, dynamic stretching (DS) was compared to static stretching (SS). To test the warm-up effect, DS was compared to submaximal isometric muscle activity (SIMA) with similar contraction intensity. A control condition served as reference. These four conditioning activities were time matched (2×20s) and tested on separate days on 13 volunteers. Electrical neurostimulation was applied to investigate muscle mechanical properties (peak doublet torq…

AdultMale[SDV.MHEP.RSOA] Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal systemsubmaximal contractions[SDV.MHEP] Life Sciences [q-bio]/Human health and pathologyCross-Over StudiesWarm-Up Exercisemuscle stretchingpassive resistive torquefascicles extensibilityPre-exercise interventionMuscle Strength DynamometerBiomechanical PhenomenaTendonsYoung Adultcontractile propertiesTorqueMuscle Stretching ExercisesHumansMuscle SkeletalResearch ArticleUltrasonography
researchProduct

Addition of a second opioid may improve opioid response in cancer pain: preliminary data

2004

Recent experimental data suggest a possible use of an opioid combination to improve analgesia. In cancer patients, a rapid opioid escalation due to either worsening of the pain condition or the development of tolerance is a critical phase, as this condition is associated with a negative prognosis. The aim of this study was to assess the effects of adding a second opioid at low doses in patients with a poor analgesic benefit after dose escalation. Fourteen patients receiving strong opioids who had increased their dosage more than 100% in the last week unsuccessfully were randomly chosen to add a second opioid to the first using an initial equivalent dosage of 20% of the previous therapy. The…

AdultMalecancer painMaximum Tolerated DosePain medicineAnalgesicPainRisk AssessmentSeverity of Illness IndexDrug Administration ScheduleStatistics Nonparametriclaw.inventionPharmacotherapyRandomized controlled triallawNeoplasmsMedicineHumansTerminally IllProspective StudiesKarnofsky Performance StatusAdverse effectAgedPain MeasurementProbabilityTerminal CareDose-Response Relationship DrugMorphinebusiness.industryMiddle AgedClinical trialAnalgesics OpioidFentanylTreatment OutcomeOncologyOpioidopioid responseAnesthesiaopioid treatmentDrug Therapy CombinationFemaleCancer painbusinessmedicine.drug
researchProduct

Extreme duration exercise affects old and younger men differently.

2022

Aim & Methods: Extreme endurance exercise provides a valuable research model for understanding the adaptive metabolic response of older and younger individuals to intense physical activity. Here, we compare a wide range of metabolic and physiologic parameters in two cohorts of seven trained men, age 30 ± 5 years or age 65 ± 6 years, before and after the participants travelled ≈3000 km by bicycle over 15 days. Results: Over the 15-day exercise intervention, participants lost 2–3 kg fat mass with no significant change in body weight. V̇O2max did not change in younger cyclists, but decreased (p = 0.06) in the older cohort. The resting plasma FFA concentration decreased markedly in both gro…

AdultMalecyclingPhysiologyRestendurance exerciseMASSINTRAMYOCELLULAR CERAMIDE ACCUMULATIONH2O2 EMISSIONenergy metabolismHumansCONTROLLED TOURMuscle SkeletalExerciseTriglyceridesAgedaerobic fitnessMORTALITYagingBody WeightENERGY-EXPENDITUREfat oxidationMiddle AgedINSULINPHYSICAL-ACTIVITYMAXIMAL FAT OXIDATIONPhysical EnduranceSKELETAL-MUSCLEmuscle biopsySettore M-EDF/01 - Metodi E Didattiche Delle Attivita' MotorieActa physiologica (Oxford, England)
researchProduct

Infant crying: pattern of weeping, recognition of emotion and affective reactions in observers.

2012

This study has three objectives: a) to describe the main differences in the crying patterns produced by the three affective states most closely related to crying: fear, anger and pain; b) to study the adults' accuracy in the recognition of the affective states related to the infant's crying, and c) to analyze the emotional reaction that infant crying elicits in the observers. Results reveal that the main differences appear in the ocular activity and in the pattern of weeping. The infants maintain their eyes open during the crying produced by fear and anger, but in the case of crying provoked by painful stimuli, the eyes remain closed almost all the time. In regard to the pattern of weeping,…

AdultMaleendocrine systemLinguistics and Languagemedia_common.quotation_subjectEmotionsPainCryingAngerAngerLanguage and LinguisticsDevelopmental psychologyYoung AdultEmotional reactionmedicineHumansInfant cryingEyes openGeneral Psychologymedia_commonAgedMaximum intensityFacial expressionCryingSocial perceptionInfantRecognition PsychologyFearMiddle AgedFacial ExpressionSocial PerceptionInfant BehaviorFemalemedicine.symptomPsychologyThe Spanish journal of psychology
researchProduct

Validity of Using Velocity to Estimate Intensity in Resistance Exercises in Men and Women

2020

AbstractThis study aimed to examine the validity of using bar velocity to estimate relative load in squat and bench-press exercises for both young men and women. Twenty-five men and 25 women performed a progressive loading test up to 1-RM in the squat and bench-press exercises, which were repeated after 2-weeks. Relationships between mean propulsive velocity and%1-RM were analysed. A second-order polynomial equation for predicting the corresponding velocity of each percentage of 1-RM was developed for men (validation). This equation was then applied in women (cross-validation). Moreover, a specific equation for women was developed (validation) and was also applied in a sub-sample of women (…

AdultMaleloading intensitynopeuspunnerrusWeight LiftingMovementPhysical Therapy Sports Therapy and RehabilitationSquatBench presssukupuoliUpper ExtremityWeight-Bearing03 medical and health sciencesYoung Adult0302 clinical medicineSex FactorsSex factorsOne-repetition maximumMaximal strengthStatisticsgenderHumansOrthopedics and Sports MedicineMathematicssuorituskykynopeusvoimaData interpretationReproducibility of ResultsResistance Training030229 sport sciencesIntensity (physics)Lower Extremitymaximal strengthData Interpretation StatisticalFemaleathletic performanceone-repetition maximum030217 neurology & neurosurgeryvelocity-based training
researchProduct

Relationships between maximal oxygen uptake and endothelial function in healthy male adults: a preliminary study

2010

Aerobic capacity, as indicated by maximal oxygen uptake (VO(2) max) has an important role in contrasting the traditional cardiovascular risk factors and preventing cardiovascular morbidity and mortality. It is known that endothelial function, measured as flow-mediated dilation (FMD) of the brachial artery, is strictly linked to atherogenesis and cardiovascular risk. However, the relationship between VO(2) max and FMD has not been fully investigated especially in healthy non-obese subjects. This preliminary study cross-sectionally investigated the relationship between VO(2) max and FMD in 22 non-obese, healthy sedentary male subjects. Dividing the cohort in two subgroups of 11 subjects each …

AdultMalemedicine.medical_specialtyAdolescentBrachial ArteryEndocrinology Diabetes and MetabolismCardiovascular risk factorsFlow mediated dilationBody Mass IndexFat massOxygen ConsumptionEndocrinologymedicine.arteryInternal medicineDiabetes mellitusInternal MedicinemedicineBody Fat DistributionHumansBrachial arteryAerobic capacityUltrasonographybusiness.industryVO2 maxGeneral MedicineMiddle Agedendothelial function FMD VO2max maximal aerobic capacitymedicine.diseaseVasodilationCarotid ArteriesCross-Sectional StudiesEndocrinologyRegional Blood FlowCohortBody CompositionEndothelium Vascularbusinesscirculatory and respiratory physiologyActa Diabetologica
researchProduct

Reliability of different models to assess heart rate recovery after submaximal bicycle exercise.

2011

Abstract Objectives : Different models to assess HR recovery have been developed but knowledge of their reliability is poor at different submaximal exercise intensities and recovery durations. Our aim was to determine the reliability of HR recovery after a test on a cycle ergometer. Design : Twenty-one healthy individuals performed a submaximal exercise at 65% and 80% HR max followed by passive recovery. The exercise was repeated (retest) within 2 weeks to assess reliability. Method : HR recovery was assessed by 8 models, based on monoexponential kinetics or absolute recovery (recovered HR at fix time points). Intraclass correlation coefficient (ICC) and standard error of measurement (SEM, …

AdultMalemedicine.medical_specialtyAdolescentIntraclass correlationPassive recoveryPhysical Therapy Sports Therapy and RehabilitationSubmaximal exerciseModels BiologicalYoung AdultHeart RateInternal medicineHeart ratemedicineHumansOrthopedics and Sports MedicineExerciseReliability (statistics)SimulationExercise Tolerancebusiness.industryRepeatabilityRecovery of FunctionBicyclingStandard errorSpainCardiologyExercise intensityExercise TestLinear ModelsPhysical EnduranceFemalebusinessJournal of science and medicine in sport
researchProduct

Capecitabine plus oxaliplatin (CapOx) versus capecitabine plus gemcitabine (CapGem) versus gemcitabine plus oxaliplatin (mGemOx): final results of a …

2007

Abstract Background To compare the efficacy and safety of three different chemotherapy doublets in the treatment of advanced pancreatic cancer (PC). Patients and methods At total of 190 patients were randomly assigned to receive capecitabine 1000 mg/m2 twice daily on days 1–14 plus oxaliplatin 130 mg/m2 on day 1 (CapOx), capecitabine 825 mg/m2 twice daily on days 1–14 plus gemcitabine 1000 mg/m2 on days 1 and 8 (CapGem) or gemcitabine 1000 mg/m2 on days 1 and 8 plus oxaliplatin 130 mg/m2 on day 8 (mGemOx). Treatment cycles were repeated every three weeks. The primary end point was progression-free survival (PFS) rate at 3 months; secondary end points included objective response rate, carboh…

AdultMalemedicine.medical_specialtyAdolescentMaximum Tolerated DoseOrganoplatinum CompoundsPhases of clinical researchKaplan-Meier EstimateDeoxycytidineRisk AssessmentGastroenterologyDisease-Free SurvivalDrug Administration ScheduleCapecitabineInternal medicineAntineoplastic Combined Chemotherapy ProtocolsmedicineHumansSingle-Blind MethodProgression-free survivalInfusions IntravenousCapecitabineAgedNeoplasm StagingProbabilityDose-Response Relationship Drugbusiness.industryCAPOX RegimenHematologyMiddle AgedImmunohistochemistrySurvival AnalysisGemcitabineGemcitabineOxaliplatinSurgeryOxaliplatinPancreatic NeoplasmsRegimenTreatment OutcomeOncologyTolerabilityFemaleFluorouracilbusinessFollow-Up Studiesmedicine.drugAnnals of Oncology
researchProduct

Effects of a 12-week strength training program on experimented fencers' movement time.

2014

The purpose of this study was to determine the effects of a 12-week strength training program on movement time (MT) on fencers of national level. Twelve male fencers were randomly divided into 2 groups: the control group (CG: N = 6; age, 22.3 ± 8.1 years) and the treatment group (TG: N = 6; age, 24.8 ± 7.2 years). The CG fencers followed the standard physical conditioning program, which was partially modified for the TG. The TG participated in a 12-week strength training program divided into 2 parts: maximal strength training, including weightlifting exercises (2 days a week for 6 weeks) and explosive strength training, with combined weights and plyometric exercises (2 days a week for 6 wee…

AdultMalemedicine.medical_specialtyAdolescentWeight LiftingStrength trainingMovementPhysical Therapy Sports Therapy and RehabilitationPlyometric ExerciseAthletic Performancemedicine.disease_causeMuscle massYoung AdultJumpingMaximal strengthmedicinePlyometricsHumansOrthopedics and Sports MedicineNational levelMuscle StrengthPhysical conditioningbusiness.industryExplosive strengthResistance TrainingGeneral MedicinePhysical therapyExercise TestbusinessPhysical Conditioning HumanJournal of strength and conditioning research
researchProduct

Neuromuscular and physiological variables evolve independently when running immediately after cycling

2015

International audience; During the early period of running after cycling, EMG patterns of the leg are modified in only some highly trained triathletes. The majority of studies have analysed muscle EMG patterns at arbitrary, predetermined time points. The purpose of this study was to examine changes to EMG patterns of the lower limb at physiologically determined times during the cycle-run transition period to better investigate neuromuscular adaptations. Six highly trained triathletes completed a 10 min isolated run (IR), 30 min of rest, then a 20 min cycling procedure, before a 10 min transition run (C-R). Surface EMG activity of eight lower limb muscles was recorded, normalised and quantif…

AdultMalemedicine.medical_specialtyAdolescentenergy-costperformance-levelBiophysicsNeuroscience (miscellaneous)submaximal exerciseBiologyTriathlonLower limbRunningPhysical medicine and rehabilitationEMGmuscle-fiber typeHeart ratemedicine[SDV.MHEP.PHY]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO]Humansolympic-triathlonMuscle SkeletalCycle-runReproducibility[ SDV.MHEP.PHY ] Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO]Cyclingslow componentOxygen uptakeAdaptation Physiologicalpriming exerciseBicyclingbody regionso-2 uptake kineticsprior heavy exerciseMotor unit recruitmentTransitionPhysical therapyoxygen-uptake kineticsNeurology (clinical)Cycling
researchProduct