Search results for "Maxima"
showing 10 items of 371 documents
Relationship Between Patient-Reported Outcomes and Clinical Outcomes in Patients With Morquio A Syndrome
2019
Abstract This cross-sectional analysis assessed the correlation between patient-reported outcomes (PROs) and clinical outcomes in 24 German patients with Morquio A. Clinical outcomes included 6-minute walk test (6MWT), 3-minute stair climb (3MSC) test, and joint range of motion as measures for endurance/mobility, forced vital capacity (FVC) and maximum voluntary ventilation (MVV) as measures for respiratory function, and height as an important manifestation. The PROs included the EuroQoL (EQ) 5D-5L (EQ5D-5L), to measure health-related QoL (HRQoL), and patients’ rating of their ability to walk, climb, or breathe. In adults, endurance and pulmonary function measures and height showed strong a…
Vitamin and Mineral Supplementation and Neuromuscular Recovery after a Running Race
2006
International audience; Purpose: This double-blind study investigated the effects of vitamin and mineral complex supplementation on the neuromuscular function of the knee-extensor muscles after a prolonged trail running race. Methods: Twenty-two well-trained endurance runners took either placebo (Pl group) or vitamins and minerals (Vm group) for 21 d before the race and for 2 d after the race. Maximal voluntary contractions (MVC) and surface EMG activity of the vastus lateralis (VL) muscle were recorded before (pre) and 1 h (post), 24 h (post 24) and 48 h (post 48) after the race. Central activation ratio (CAR), neural (M-wave), and contractile (muscular twitch) properties of the quadriceps…
Gradient design for liquid chromatography using multi-scale optimization.
2017
Abstract In reversed phase-liquid chromatography, the usual solution to the “general elution problem” is the application of gradient elution with programmed changes of organic solvent (or other properties). A correct quantification of chromatographic peaks in liquid chromatography requires well resolved signals in a proper analysis time. When the complexity of the sample is high, the gradient program should be accommodated to the local resolution needs of each analyte. This makes the optimization of such situations rather troublesome, since enhancing the resolution for a given analyte may imply a collateral worsening of the resolution of other analytes. The aim of this work is to design mul…
Determination of the apparent activation energy of dielectric relaxation phenomena by means of the representation of ε” as a function of T at constan…
1984
Abstract The main purpose of this work is to justify the use of the positions of the maxima of e” versus T curves when calculating the apparent activation energy in secondary dielectric relaxations or in the relaxation associated with the glass transition. To exemplify this, phenomenological models as well as experimental results for methacrylic polymers are discussed.
On local optima in minimum time control of the restricted three-body problem
2016
International audience; The structure of local minima for time minimization in the controlled three-body problem is studied. Several homotopies are systematically used to unfold the structure of these local minimizers, and the resulting singularity of the path associated with the value function is analyzed numerically.
Convergence rate of a relaxed inertial proximal algorithm for convex minimization
2018
International audience; In a Hilbert space setting, the authors recently introduced a general class of relaxed inertial proximal algorithms that aim to solve monotone inclusions. In this paper, we specialize this study in the case of non-smooth convex minimization problems. We obtain convergence rates for values which have similarities with the results based on the Nesterov accelerated gradient method. The joint adjustment of inertia, relaxation and proximal terms plays a central role. In doing so, we highlight inertial proximal algorithms that converge for general monotone inclusions, and which, in the case of convex minimization, give fast convergence rates of values in the worst case.
Computerized delimitation of odorant areas in gas-chromatography-olfactometry by kernel density estimation: Data processing on French white wines
2017
International audience; GC-O using the detection frequency method gives a list of odor events (OEs) where each OE is described by a linear retention index (LRI) and by the aromatic descriptor given by a human assessor. The aim of the experimenter is to gather OEs in a total olfactogram on which he tries to delimit odorant areas (OAs), then to compute each detection frequency. This paper proposes a computerized mathematical method based on kernel density estimation that makes up the total olfactogram as continuous and differentiable function from the OEs LRI only. The corresponding curve looks like a chromatogram, the peaks of which are potential OAs. The limits of an OA are the LRI of the t…
Changing European storm loss potentials under modified climate conditions according to ensemble simulations of the ECHAM5/MPI-OM1 GCM
2007
Abstract. A simple storm loss model is applied to an ensemble of ECHAM5/MPI-OM1 GCM simulations in order to estimate changes of insured loss potentials over Europe in the 21st century. Losses are computed based on the daily maximum wind speed for each grid point. The calibration of the loss model is performed using wind data from the ERA40-Reanalysis and German loss data. The obtained annual losses for the present climate conditions (20C, three realisations) reproduce the statistical features of the historical insurance loss data for Germany. The climate change experiments correspond to the SRES-Scenarios A1B and A2, and for each of them three realisations are considered. On average, insure…
Do Women and Men over 70 Years Old Similarly Benefit from a One-Year Training Program?
2010
Background and Aims : Exercise capacity declines with age and is improved with exercise training. The aim of this study was to characterize the effects of a one-year combined exercise training in subjects over 70 years old, and to examine the eventual differences obtained between men and women. Methods : After baseline evaluation, 24 subjects (12 men and 12 women) over 70 years old underwent moderate intensity training with aerobic and resistance exercises, 3 hours a week over one year. Workload, oxygen uptake (VO2) and heart rate were measured during a symptom-limited exercise test. The distance walked in 6 minutes (6-MWT) was also registered, and the maximal strength was measured on knee …
Adaptations neuromusculaires des muscles extenseurs du genou : contractions fatigantes uni- vs bi-latérales
2010
The aim of this work was to determine i) the influence of the level of absolute force on the duration of the endurance time, and subsequent neuromuscular alterations in same individual at the end of an exercise performed at the same relative intensity, with one or two legs, ii) the influence of central drive on the force capacity production of the knee extensor muscles during unilateral (UL) vs. bilateral (BL) contractions, iii) activation mechanisms evolution for a serie of submaximal evoked contractions by electrostimulation (EMS). The results of the first study confirm that the endurance limit depends on the level of absolute force for the same individual, contraction duration for UL is …