Search results for "Mechanism"
showing 10 items of 1835 documents
Selected theories of ageing organisms
2016
Starzenie się jest złożonym procesem biologicznym, którego mechanizmy nie do końca są znane. Istnieje wiele teorii dotyczących mechanizmów tego procesu. W pracy opisano cztery teorie, które poruszają molekularny aspekt starzenia się organizmów. Jest to teoria telomerowa zakładająca wpływ długości telomerów na długość życia. Telomery to zlokalizowane na końcach chromosomów struktury nukleoproteinowe, chroniące przed utratą informacji genetycznej, ulegające skróceniu z każdym cyklem komórkowym. Nadmiernie skrócone telomery sprzyjają powstawaniu nowotworów, starzeniu się komórki i organizmów. Teoria mitochondrialna mówi o wpływie kumulujących się mutacji w mtDNA na procesy starzenia. Według ni…
Integracja w dezintegracji i dezintegracja w integracji: determinanty mechanizmów integracyjnych w Unii Europejskiej
2017
W dyskusji o przyszłości UE strategicznym wątkiem stała się kwestia integracji zróżnicowanej, której różne warianty zaczęły jawić się jako modus operandi Unii Europejskiej, co stało się przedmiotem kontrowersji między państwami członkowskimi. Co istotne, debacie poświęconej integracji zróżnicowanej zaczęły towarzyszyć rozważania na temat dezintegracji. W niniejszym artykule podjęta została próba zdefiniowania dezintegracji przy założeniu, że powinna być ona definiowana poprzez integrację, a także iż tak zaprojektowany proces definiowania nie może ograniczać się do wnioskowania o jednotorowej przeciwstawności dezintegracji względem integracji i vice versa. Wynika to z przekonania, że Unia Eu…
Experiencing anger in a social interaction: The role of personality
2018
Abstract Although prior research has shown a relationship between the Big Five personality factors and trait anger, evidence that links these personality traits to the experience of state anger is rare. The current study investigated the effect of the Big Five personality traits on the state anger experience after a provocation in a staged social interaction and how status differences moderate these personality effects in an academic sample. In the equal status condition (N = 131, 56% female, aged 18 to 37) participants were provoked by a confederate; in the low status condition (N = 125, 55% female, aged 18 to 51) anger was instead provoked by the experimenter. In both conditions, individu…
The power of status: What determines one's reactions to anger in a social situation?
2017
Abstract The present study examined how social status and gender determine anger expression and behavioral reactions toward experienced anger. In two experiments, anger was induced in a staged social interaction. Behavioral anger reactions were judged by observers. In Experiment 1 ( equal status condition ; N = 110) participants were provoked by a confederate, in Experiment 2 ( low status condition ; N = 116) participants were provoked by the experimenter. We found that participants expressed their anger to a lesser extent, were less resistant, and engaged in submissive behaviors if they had a lower status than the anger-target. As expected, gender had a moderating effect: While women's a…
Spatially Resolved Broadband Synchrotron Emission from the Nonthermal Limbs of SN1006
2018
We present ~400ks NuSTAR observations of the northeast (NE) and southwest (SW) non-thermal limbs of the Galactic SNR SN1006. We discovered three sources with X-ray emission detected at >50keV. Two of them are identified as background AGN. We extract the NuSTAR spectra from a few regions along the non-thermal limbs and jointly analyze them with the XMM-Newton spectra and the radio data. The broad-band radio/X-ray spectra can be well described with a synchrotron emission model from a single population of CR electrons with a power law energy distribution and an exponential cutoff. The power law index of the electron particle distribution function (PDF) is ~1.88-1.95 for both the NE and SW l…
Gene expression patterns associated with caste and reproductive status in ants: worker-specific genes are more derived than queen-specific ones.
2013
Variation in gene expression leads to phenotypic diversity and plays a central role in caste differentiation of eusocial insect species. In social Hymenoptera, females with the same genetic background can develop into queens or workers, which are characterized by divergent morphologies, behaviours and lifespan. Moreover, many social insects exhibit behaviourally distinct worker castes, such as brood-tenders and foragers. Researchers have just started to explore which genes are differentially expressed to achieve this remarkable phenotypic plasticity. Although the queen is normally the only reproductive individual in the nest, following her removal, young brood-tending workers often develop …
Emotional Seesaw, Compliance, and Mindlessness
2001
Research on emotion conducted so far has ignored situations where the subject experiences a certain emotion, but where the external stimulus that evoked and upholds this emotion suddenly disappears. This kind of situation, however, is relatively common in everyday life. This article attempts to recognize certain consequences of those conditions under which the stimuli justifying our experience of such emotional states as fear or joy suddenly disappear. Research done to date by the author and colleagues indicates increased compliance of the subject when addressed with various requests, commands, or suggestions in the situation termed here “emotional seesaw.” The classical “live” example tha…
The role of shame and guilt in social anxiety disorder
2021
Abstract Research suggests that shame and guilt may play a role in anxiety disorders. For social anxiety disorder (SAD), however, only a few studies investigated patients with the primary diagnosis of SAD. Thus, further research on shame and guilt in SAD is required. A secondary analysis of Data from the SOPHO-NET multicenter treatment study was performed. In a large sample of N = 495 patients with the primary diagnosis of SAD the relationship between shame and guilt with symptoms of social anxiety, depression, and interpersonal problems was examined by means of correlation analysis and additionally, a hierarchical linear regression analysis. To assess SAD, the German version of the Structu…
Gene expression is stronger associated with behaviour than with age and fertility in ant workers
2018
AbstractThe ecological success of social insects is based on division of labour, not only between queens and workers, but also among workers. Whether a worker tends the brood or forages is strongly influenced by age, fertility and nutritional status, with brood carers being younger, more fecund and corpulent. Here, we experimentally disentangle behaviour from age and fertility inTemnothorax longispinosusant workers and analyse how these parameters are linked to whole-body gene expression. Our transcriptome analysis reveals four times more genes associated with behaviour than with age and only few fertility-associated genes. Brood carers exhibited an upregulation of genes involved in lipid b…
Anger: Adrenaline receptors do not allow us to be too sinful
2013
All of us feel angry once in a while, but if anger turns into a chronic state of mind it is not only annoying to those around us, it may also make us ill. Much of the acute anger reaction is mediated by catecholamines acting on β-adrenoceptors. Chronic activation of these receptors leads to their desensitization, protecting us at least partly from the adverse effects of sustained anger.