Search results for "Memory."

On Constructing Persistent Identifiers with Persistent Resolution Targets

2016

Persistent Identifiers (PID) are the foundation referencing digital assets in scientific publications, books, and digital repositories. In its realization, PIDs contain metadata and resolving targets in form of URLs that point to data sets located on the network. In contrast to PIDs, the target URLs are typically changing over time; thus, PIDs need continuous maintenance -- an effort that is increasing tremendously with the advancement of e-Science and the advent of the Internet-of-Things (IoT). Nowadays, billions of sensors and data sets are subject of PID assignment. This paper presents a new approach of embedding location independent targets into PIDs that allows the creation of maintena…

Working memory performance is tied to stimulus complexity

2021

1. Summary Working memory is the cognitive capability to maintain and process information over short periods. Recent behavioral and computational studies have shown that increased visual information of the presented stimulus material is associated with enhanced working memory performance. However, the underlying neural correlates of this association are unknown. To identify how stimuli of different visual information levels affect working memory performance, we conducted behavioral experiments and single unit recordings in the avian analog of the prefrontal cortex, the nidopallium caudolaterale (NCL). On the behavioral level, we confirmed that feature-rich complex stimuli demonstrated highe…

The effects of collaboration and punishment on prospective memory performance in a group setting

2020

Contains fulltext : 225210.pdf (Publisher’s version ) (Open Access) Remembering to perform a delayed intention is termed prospective memory (PM). Often delayed intentions are shared by more than one person; however, there is a dearth of studies examining PM in social settings. We aimed to investigate whether the potential consequences of one's behavior across diverse group settings influence PM performance in event- and time-based tasks. A total of 207 participants were randomly allocated to either an individual, collaborative, or collaborative plus penalty motivation condition and were tested in a 2- or 3-person setting. For the time-based PM task, participants responded less timely in the…

Neurodidáctica y la implicación de emociones en el aprendizaje

2012

The purpose of this article is to highlight the importance of a new discipli- ne named neurodidactics; also aims to emphasize the role that emotions play in learning. The interaction between teacher and student that is based on the cir- cular model of motivation, cognition, memory and emotions, can be organized and implemented through neurodidactics, whose main objective is to create tea- ching methodologies for an ecology of mind. This discipline is at the crossroads between neurobiology and science education since it is based on the principle that any learning process itself involves a change in the brain, in that our neural networks are affected by changes. At the same time the paper set…

Electrophysiological evidence of memory-based detection of auditory regularity violations in anesthetized mice

2017

In humans, automatic change detection is reflected by an electrical brain response called mismatch negativity (MMN). Mismatch response is also elicited in mice, but it is unclear to what extent it is functionally similar to human MMN. We investigated this possible similarity by recording local field potentials from the auditory cortex of anesthetized mice. First, we tested whether the response to stimulus changes reflected the detection of regularity violations or adaptation to standard stimuli. Responses obtained from an oddball condition, where occasional changes in frequency were presented amongst of a standard sound, were compared to responses obtained from a control condition, where no…

Analysis of a spatial orientation memory in Drosophila.

2008

Flexible goal-driven orientation requires that the position of a target be stored, especially in case the target moves out of sight. The capability to retain, recall and integrate such positional information into guiding behaviour has been summarized under the term spatial working memory. This kind of memory contains specific details of the presence that are not necessarily part of a long-term memory. Neurophysiological studies in primates indicate that sustained activity of neurons encodes the sensory information even though the object is no longer present. Furthermore they suggest that dopamine transmits the respective input to the prefrontal cortex, and simultaneous suppression by GABA s…

Nucleus incertus—An emerging modulatory role in arousal, stress and memory

2011

A major challenge in systems neuroscience is to determine the underlying neural circuitry and associated neurotransmitters and receptors involved in psychiatric disorders, such as anxiety and depression. A focus of many of these studies has been specific brainstem nuclei that modulate levels of arousal via their ascending monoaminergic projections (e.g. the serotonergic dorsal raphe, noradrenergic locus ceruleus and cholinergic laterodorsal tegmental nucleus). After years of relative neglect, the subject of recent studies in this context has been the GABAergic nucleus incertus,1 which is located in the midline periventricular central gray in the ‘prepontine’ hindbrain, with broad projection…

Brain histamine and oleoylethanolamide restore behavioral deficits induced by chronic social defeat stress in mice.

2021

The physiological mechanisms underlying the complex interplay between life stressors and metabolic factors is receiving growing interest and is being analyzed as one of the many factors contributing to depressive illness. The brain histaminergic system modulates neuronal activity extensively and we demonstrated that its integrity is necessary for peripheral signals such as the bioactive lipid mediator oleoylethanolamide (OEA) to exert its central actions. Here, we investigated the role of brain histamine and its interaction with OEA in response to chronic social defeat stress (CSDS), a preclinical protocol widely used to study physio-pathological mechanisms underlying symptoms observed in d…

Heart rate accelerations during four active encoding tasks — pilot results

1997

On the cellular mechanisms underlying working memory capacity in humans

2016

The cellular processes underlying individual differences in the Working Memory Capacity (WMC) of humans are essentially unknown. Psychological experiments suggest that subjects with lower working memory capacity (LWMC), with respect to subjects with higher capacity (HWMC), take more time to recall items from a list because they search through a larger set of items and are much more susceptible to interference during retrieval. However, a more precise link between psychological experiments and cellular properties is lacking and very difficult to investigate experimentally. In this paper, we investigate the possible underlying mechanisms at the single neuron level by using a computational mod…