Search results for "Memory."
showing 10 items of 1949 documents
Selective deficits in episodic feeling of knowing in ageing: A novel use of the general knowledge task
2015
Failure to recall an item from memory can be accompanied by the subjective experience that the item is known but currently unavailable for report. The feeling of knowing (FOK) task allows measurement of the predictive accuracy of this reflective judgement. Young and older adults were asked to provide answers to general knowledge questions both prior to and after learning, thus measuring both semantic and episodic memory for the items. FOK judgements were made at each stage for all unrecalled responses, providing a measure of predictive accuracy for semantic and episodic knowledge. Results demonstrated a selective effect of age on episodic FOK resolution, with older adults found to have impa…
Do healthy elders, like young adults, remember animates better than inanimates? An adaptive view
2016
International audience; Background/Study Context: It has been found that young adults remember animates better than inanimates. According to the adaptive view of human memory, this is due to the fact that animates are more important for fitness purposes than inanimates. This effect has been ascribed to episodic memory, where older people exhibit difficulties. Methods: Here the authors investigated whether the animacy effect in memory also occurs for healthy older adults. Older and young adults categorized words for their animacy characteristics and were then given an unexpected recognition test on the words using the Remember/Know paradigm. Executive functions were also evaluated using seve…
Pure Progressive Amnesia and the APPV717G Mutation
2009
We report an isolated, slowly progressive, pure amnestic phenotype in a 59-year-old member of a family affected by autosomal dominant familial Alzheimer disease. Early-onset Alzheimer disease in this family was associated with a V717G mutation in the amyloid precursor protein gene (APP). Subjective impairment of episodic memory began in our subject at the age of 44 years and subsequent, longitudinal neuropsychologic assessment confirmed progressive, severe, global impairment of memory functions over a period of 14 years with preservation of other cognitive domains. The mean annual hippocampal atrophy rate, determined by volumetric magnetic resonance imaging was intermediate between values p…
Differences in false recollection according to the cognitive reserve of healthy older people
2016
We present an associative recognition experiment comparing three samples of healthy people (young people, older people with high cognitive reserve [HCR], and older people with low cognitive reserve [LCR], with each sample consisting of 40 people), manipulating stimuli repetition during the study phase. The results show significant differences among the three samples in their overall performance. However, these differences are not due to a different use of familiarity, but rather due to a different way of using recollection: although there are no differences in the hit rates between the HRC and LRC samples, the LCR group makes significantly more recollective false alarms than the HCR group. …
Altered effective connectivity in drug free schizophrenic patients
2003
The present fMRI study aimed to investigate effective connectivity within a cortical-subcortical-cerebellar information processing network in drug free schizophrenic patients while performing a 2-back working memory task. The finding of enhanced thalamo-cortical and cortico-cortical intrahemispheric connectivity could be interpreted as a compensatory increase of neuronal connection strength consistent with a model of cortical inefficiency in schizophrenic patients. Additionally, the result could be integrated into a model of deficient thalamo-cortical filter functions. Conversely, lower interhemispheric connectivity of the frontal and parietal association cortex appears to be the functional…
Adult counting is resource demanding.
2004
Several recent studies on both the development of counting and working-memory span tasks have provided results that could be interpreted as ruling out any cognitive resource model for counting. The aim of this study was to test the hypothesis that, even in adults, counting is a demanding task that requires the allocation of cognitive resources. In a first experiment, we asked adults to count arrays of dots while maintaining 5 items in memory (either digits or letters). As we predicted, the concurrent memory load did not increase the rate of errors but induced longer counting times. In a second experiment, we asked adults to count using either the numeric chain or the alphabet while they mai…
Chronometric evidence for memory retrieval in causal conditional reasoning: The case of the association strength effect
2005
According to many models of conditional reasoning, correct responses to the uncertain forms affirmation of consequent (AC) and denial of antecedent (DA) rely on the retrieval of an alternative antecedent from semantic memory. The main prediction issuing from this hypothesis of online retrieval is that the associative strength of the relevant information in long-term memory affects the latency of its retrieval and then of the correct response of uncertainty to AC and DA. This prediction was tested in 64 adults who performed a syllogism evaluation task with familiar causal conditional premises. As predicted, correct responses of uncertainty to AC and DA were not only more frequent but also fa…
The role of the thalamus in amnesia: a tractography, high-resolution MRI and neuropsychological study.
2008
Although it is well established that thalamic lesions may lead to profound amnesia, the precise contribution of thalamic sub-regions to memory remains unclear. In an influential article Aggleton and Brown proposed that recognition memory depends on two processes supported by distinct thalamic and cortical structures. Familiarity is mediated by the mediodorsal (MD) thalamic nucleus and the entorhinal/ perirhinal cortex. Recollection ismediated by the anterior thalamic nucleus (AN), the mamillothalamic tract (MTT) and the hippocampus. The authors also suggested that the lateral dorsal nucleus (LD) may contribute to the thalamic/hippocampus system, thereby implying that the LD may play a role …
Speed on the dance floor : auditory and visual cues for musical tempo
2016
Musical tempo is most strongly associated with the rate of the beat or “tactus,” which may be defined as the most prominent rhythmic periodicity present in the music, typically in a range of 1.67–2 Hz. However, other factors such as rhythmic density, mean rhythmic inter-onset interval, metrical (accentual) structure, and rhythmic complexity can affect perceived tempo (Drake et al., 1999 and London, 2011Drake, Gros, & Penel, 1999; London, 2011). Visual information can also give rise to a perceived beat/tempo (Iversen, et al., 2015), and auditory and visual temporal cues can interact and mutually influence each other (Soto-Faraco and Kingstone, 2004 and Spence, 2015). A five-part experiment w…
The feeling of familiarity for music in patients with a unilateral temporal lobe lesion: A gating study
2015
International audience; Previous research has indicated that the medial temporal lobe (MTL), and more specifically the perirhinal cortex, plays a role in the feeling of familiarity for non-musical stimuli. Here, we examined contribution of the MTL to the feeling of familiarity for music by testing patients with unilateral MTL lesions. We used a gating paradigm: segments of familiar and unfamiliar musical excerpts were played with increasing durations (250, 500, 1000, 2000, 4000 ms and complete excerpts), and participants provided familiarity judgments for each segment. Based on the hypothesis that patients might need longer segments than healthy controls (HC) to identify excerpts as familia…