Search results for "Memory"
showing 10 items of 2004 documents
Novel modes of rhythmic burst firing at cognitively-relevant frequencies in thalamocortical neurons.
2008
It is now widely accepted that certain types of cognitive functions are intimately related to synchronized neuronal oscillations at both low (alpha/theta) (4-7/8-13 Hz) and high (beta/gamma) (18-35/30-70 Hz) frequencies. The thalamus is a key participant in many of these oscillations, yet the cellular mechanisms by which this participation occurs are poorly understood. Here we describe how, under appropriate conditions, thalamocortical (TC) neurons from different nuclei can exhibit a wide array of largely unrecognised intrinsic oscillatory activities at a range of cognitively-relevant frequencies. For example, both metabotropic glutamate receptor (mGluR) and muscarinic Ach receptor (mAchR) …
Staggered magnetic nanowire devices for effective domain-wall pinning in racetrack memory
2019
Domain-wall memory devices, in which the information is stored in nanowires, are expected to replace hard disk drives. A problem that remains to be solved in domain-wall memory is to pin the domain walls in a controllable manner at the nanometer scale using simple fabrication. We demonstrate the possibility to stabilize domain walls by making staggered nanowires. Controllable domain-wall movement is exhibited in permalloy nanowires using magnetic fields where the pinning field is about 10 mT. The pinning field and stability of the domain walls can be increased by adjusting the offset dimensions of the staggered nanowires. Domain-wall velocities of about 200 m/s are computed for the experime…
Transmission of Genetic Properties in Permutation Problems: Study of Lehmer Code and Inversion Table Encoding
2021
Solution encoding describes the way decision variables are represented. In the case of permutation problems, the classical encoding should ensure that there are no duplicates. During crossover operations, repairs may be carried out to correct or avoid repetitions. The use of indirect encoding aims to define bijections between the classical permutation and a different representation of the decision variables. These encodings are not sensitive to duplicates. However, they lead to a loss of genetic properties during crossbreeding. This paper proposes a study of the impact of this loss both in the space of decision variables and in that of fitness values. We consider two indirect encoding: the …
FUNCIONES EJECUTIVAS Y MOTIVACIÓN DE NIÑOS CON TRASTORNO DE ESPECTRO AUTISTA (TEA) Y TRASTORNO POR DÉFICIT DE ATENCIÓN CON HIPERACTIVIDAD (TDAH)
2016
Resumen Objetivos. Comparar el perfil de niños con trastorno del espectro autista (TEA) y niños con trastorno por déficit de atención con hiperactividad (TDAH), presentación combinada, en componentes del funcionamiento ejecutivo (FE) y en comportamientos que están asociados al aprendizaje. Método. Participaron en esta investigación 16 niños con un diagnóstico clínico de TDAH y 16 niños con un diagnóstico clínico de TEA con alto nivel de funcionamiento que habían sido diagnosticados en servicios de Neuropediatría de la Comunidad Valenciana. Las edades estaban comprendidas entre 7 y 11 años. El 94% eran varones y se encontraban escolarizados en aulas ordinarias, estando equiparados los dos …
The Power of Odor Persuasion: The Incorporation of Olfactory Cues in Virtual Environments for Personalized Relaxation
2021
Olfaction is the most ancient sense and is directly connected with emotional areas in the brain. It gives rise to perception linked to emotion both in everyday life and in memory-recall activities. Despite its emotional primacy in perception and its role in sampling the real physical world, olfaction is rarely used in clinical psychological settings because it relies on stimuli that are difficult to deliver. However, recent developments in virtual-reality tools are creating novel possibilities for the engagement of the sense of smell in this field. In this article, we present the relevant features of olfaction for relaxation purposes and then discuss possible future applications of involvi…
Comparative neuroscience of stimulant-induced memory dysfunction: role for neurogenesis in the adult hippocampus.
2010
The discovery that the addictive drugs impair neurogenesis in the adult hippocampus has prompted the elaboration of new biological hypotheses to explain addiction and drug-induced cognitive dysfunction. Considerable evidence now implicates the process of adult neurogenesis in at least some critical components of hippocampal-dependent memory function. In experimental models, psychomotor stimulant drugs produce alterations in the rate of birth, survival, maturation and functional integration of adult-born hippocampal neurons. Thus some of the deleterious consequences of drug abuse on memory could result from the neurotoxic actions of drugs on adult hippocampal neurogenesis. In this review, we…
A common thread for pain and memory synapses? Brain-derived neurotrophic factor and trkB receptors.
2003
Recent evidence indicates that trophic factors can exert fast effects on neurones and so alter synaptic plasticity. Here, we focus on brain-derived neurotrophic factor (BDNF), which exerts a modulatory action at hippocampal synapses that are involved in learning and memory, and at the first pain synapse between primary sensory neurones and dorsal horn neurones. Hippocampal and sensory neurones share some properties for the release of endogenous BDNF. In the Schaffer collateral pathway of the hippocampus, binding of BDNF to high-affinity trkB receptors is essential for the induction of long-term potentiation, a specific type of synaptic plasticity. However, the consequences of BDNF binding t…
Inactivation of the interpositus nucleus blocks the conditioned response acquired by a somatosensory conditioned stimulus in rabbit eyeblink conditio…
2001
1. Earlier studies suggest that the memory trace for the conditioned eyeblink reflex is formed and maintained in the interpositus nucleus (IPN) in the deep cerebellar nuclei when either an auditory or visual stimulus is used as a conditioned stimulus (CS). 2. In the present study, the eyeblink reflex of the rabbit was conditioned to a somatosensory CS (an airpuff onto the back). 3. In well-trained animals, the IPN was reversibly inactivated by local cooling and the existence of the learned responses to the CS was then tested. 4. The reversible IPN inactivation blocked the memory trace the somatosensory CS. The finding further supports the view that IPN-mediated memory trace formation is not…
Antidepressant drugs and memory: Insights from animal studies
2007
This is a selective review of the literature concerning the effects of antidepressant drugs on animal memory, which was performed with the aid of the PubMed database. Monoamine oxidase inhibitors tend to either have no effect on memory or result in its improvement. Studies with cyclic antidepressants have reported no effect or, more often, memory impairments. Pre-training administration of selective serotonin reuptake inhibitors (SSRIs) has been shown to have either no effect on memory or undermine it (with some isolated exceptions, in which improvements have been recorded), while post-training administration of SSRIs has been demonstrated to improve memory or have no effect. A small group …