Search results for "Meri"

showing 10 items of 7596 documents

Finger ridge-count asymmetry and diversity in Andean Indians and interpopulation comparisons

1998

A separate analysis of ulnar and radial finger ridge-counts, obtained from 115 Aymara Indians (55 males and 60 females) of northern Chile, was performed. From these variables, directional asymmetry, fluctuating asymmetry, indices of bilateral asymmetry (square root of A2), and intraindividual diversity (s/square root of 5) were calculated for each sex. The results show that most bimanual differences for the ridge-counts are not statistically significant in the Aymara, except for radial counts in female first and second fingers (right hand means are larger), while most ulnar-radial differences are highly significant in both sexes (radial values exceed ulnar ones). Most sex differences do not…

AdultMaleAdolescentmedia_common.quotation_subjectUlnaBiologyAsymmetryFluctuating asymmetryFingersSex FactorsStatistical significanceEthnicityHumansChileChildSouthern Hemispheremedia_commonBilateral asymmetryIndians South AmericanRidge countRadiusAnthropologyFemaleAnatomyDermatoglyphicsDiversity (business)DemographyAmerican Journal of Physical Anthropology
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FUS mutations in sporadic amyotrophic lateral sclerosis

2011

Mutations in the FUS gene have recently been described as a cause of familial amyotrophic lateral sclerosis (ALS), but their role in the pathogenesis of sporadic ALS is unclear. We undertook mutational screening of all coding exons of FUS in 228 sporadic ALS cases, and, as previous reports suggest that exon 15 represents a mutational hotspot, we sequenced this exon in an additional 1295 sporadic cases. Six variants in six different cases were found, indicating that FUS mutations can underlie apparently sporadic ALS, but account for less than 1% of this form of disease. © 2010 .

AdultMaleAgingAmyotrophic lateral sclerosis; FUS; Italy; Sporadic disease; United States of America;AdolescentGenotypesporadic patientsDNA Mutational AnalysisALS; FUS mutations; sporadic patientsBiologymedicine.disease_causeArticlePathogenesisExonYoung AdultDNA Mutational AnalysisGenotypemedicineHumansFUS mutationsAmyotrophic lateral sclerosisChildGeneAgedGeneticsAged 80 and overMutationGeneral NeuroscienceAmyotrophic Lateral Sclerosisamyotrophic lateral sclerosis FUS geneticsExonsMiddle Agedmedicine.diseaseUnited StatesSettore MED/26 - NEUROLOGIAItalyMutationRNA-Binding Protein FUSFemaleNeurology (clinical)Geriatrics and GerontologyALSDevelopmental BiologyRNA-Binding Protein FUS
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Age Identification: A Comparison between Finnish and North-American Cultures

1998

This study examined perceptions of age among Finnish males and females in three age groups; twenty-five to thirty-nine-year-olds ( n = 446), forty to fifty-four-year-olds ( n = 482) and fifty-five to sixty-four-year-olds ( n = 427). The age perceptions of the Finnish sample were further compared with those of a North-American sample with corresponding age groups ( n = 169, n = 187, n = 222) reported by Barak, Stern, and Gould (1988). Four age concepts used were chronological age, subjective age, ideal age, and disparity age. As expected on the basis of previous studies in age identification, no difference was found between Finnish males and females in terms of subjective age. Ideal age, ho…

AdultMaleAgingSocial perceptionCultural environmentChronological ageMiddle AgedAge groupsNorth AmericaDevelopmental and Educational PsychologyHumansFemalePerceptionGeriatrics and GerontologyPsychologyFinlandDemographyThe International Journal of Aging and Human Development
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Cocaine abuse determination by ion mobility spectrometry using molecular imprinting

2016

A cocaine-based molecular imprinted polymer (MIP) has been produced by bulk polymerization and employed as selective solid-phase extraction support for the determination of cocaine in saliva samples by ion mobility spectrometry (IMS). The most appropriate conditions for washing and elution of cocaine from MIPs were studied and MIPs were characterized in terms of analyte binding capacity, reusability in water and saliva analysis, imprinting factor and selectivity were established and compared with non-imprinted polymers. The proposed MIP-IMS method provided a LOD of 18μgL-1 and quantitative recoveries for blank saliva samples spiked from 75 to 500μgL-1 cocaine. Oral fluid samples were collec…

AdultMaleAnalyteIon-mobility spectrometry02 engineering and technologyMass spectrometry01 natural sciencesBiochemistryGas Chromatography-Mass SpectrometryPolymerizationAnalytical ChemistryMolecular ImprintingCocaine-Related DisordersYoung AdultCocaineHumansSolid phase extractionSalivaIonsChromatographyChemistryElutionSpectrum AnalysisSolid Phase Extraction010401 analytical chemistryOrganic ChemistryTemperatureMolecularly imprinted polymerWaterGeneral MedicineReference Standards021001 nanoscience & nanotechnology0104 chemical sciencesMicroscopy Electron ScanningSolventsRegression AnalysisFemaleGas chromatography–mass spectrometry0210 nano-technologyMolecular imprintingJournal of Chromatography A
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Perceived Racial/Ethnic Discrimination and Psychological Outcomes Among Adult International Adoptees in Finland: Moderating Effects of Social Support…

2015

Quantitative literature on international adoptees and racial/ethnic discrimination is lacking despite results in qualitative studies from Europe and the United States that have consistently indicated how racism constantly complicates adoptees' everyday lives. To advance the literature, the present study examined the prevalence of perceived racial/ethnic discrimination among 213 adult international adoptees in Finland (59.6% women and 40.4% men, mean age 24.1 years), and the association between perceived racial/ethnic discrimination and psychological well-being indicators, including psychological distress and sleeping problems. In addition, we examined social support and sense of coherence a…

AdultMaleAsiaSense of Coherencemedia_common.quotation_subjectinternational adoptionPsycINFOsense of coherenceRacismDevelopmental psychologySocial supportYoung AdultRacismArts and Humanities (miscellaneous)psychological distresssleeping problemsAdoptionDevelopmental and Educational PsychologyHumansta516Europe EasternYoung adultAssociation (psychology)ta515Finlandmedia_commonSocial Supportracial/ethnic discriminationSouth AmericaMental healthta3123Psychiatry and Mental healthDistressta5141AfricaFemalePsychology (miscellaneous)PsychologyStress PsychologicalQualitative researchAmerican Journal of Orthopsychiatry
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Perceptions and experiences of parenthood and maternal health care among Latin American women living in Spain: A qualitative study

2013

Objective: to explore the experiences and perceptions of parenthood and maternal health care among Latin American women living in Spain. Design: an exploratory qualitative research using focus groups and thematic analysis of the discussion. Setting and participants: three focus groups with 26 women from Bolivia and Ecuador and three focus groups with 24 midwives were performed in three towns in the Valencian Community receiving a large influx of immigrants. Findings: the women interpreted motherhood as the role through which they achieve fulfilment and assumed that they were the ones who could best take care of their children. They perceived that men usually make decisions about sex and pre…

AdultMaleBoliviaLatin Americansmedia_common.quotation_subjectImmigrationEmigrants and ImmigrantsMidwiferyHealth Services AccessibilitySex FactorsNursingPregnancyMaternity and MidwiferyHumansMedicineMaternal Health ServicesCultural CompetencyMaternal WelfareReproductive healthmedia_commonHealth Services Needs and DemandParentingSocial perceptionbusiness.industryObstetrics and GynecologyFocus GroupsPatient Acceptance of Health CareFocus groupSocial PerceptionSocioeconomic FactorsSpainFemaleEcuadorThematic analysisbusinessCultural competenceQualitative researchMidwifery
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Magnetic molecularly imprinted polymers for the selective determination of cocaine by ion mobility spectrometry

2018

Abstract Magnetic molecularly imprinted polymers (MMIPs) were prepared for cocaine recognition by bulk polymerization in the presence of magnetic nanoparticles (MNPs). Two reagents (polyethylene glycol (PEG) and 3-(trimethoxysilyl)propyl methacrylate (V)) were used for MNPs modification. MMIPs were characterized and compared in terms of loading capacity, reusability, accuracy and precision for the extraction of cocaine from saliva samples. It was observed that V-MMIPs gave higher physical stability than PEG-MMIPs. Thus, V-MMIP were used for the analysis of cocaine users saliva. The developed procedure based on ion mobility spectrometry (IMS) provided limits of detection and quantification o…

AdultMaleBulk polymerizationPolymersIon-mobility spectrometry02 engineering and technologyPolyethylene glycolTandem mass spectrometryMethacrylate01 natural sciencesBiochemistryPolyethylene GlycolsAnalytical ChemistryMolecular ImprintingMagneticsYoung Adultchemistry.chemical_compoundCocaineIon Mobility SpectrometryHumansOrganosilicon CompoundsSalivaChromatography High Pressure LiquidDetection limitChromatography010401 analytical chemistryOrganic ChemistryMolecularly imprinted polymerSignal Processing Computer-AssistedGeneral Medicine021001 nanoscience & nanotechnology0104 chemical scienceschemistryMethacrylatesMagnetic nanoparticlesFemale0210 nano-technologyJournal of Chromatography A
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Etiologic Heterogeneity Among Non-Hodgkin Lymphoma Subtypes: The InterLymph Non-Hodgkin Lymphoma Subtypes Project

2014

Non-Hodgkin lymphoma (NHL) is the most common hematologic malignancy and the fifth most common type of cancer in more developed regions of the world (1). Numerous NHL subtypes with distinct combinations of morphologic, immunophenotypic, genetic, and clinical features are currently recognized (2,3). The incidence of NHL subtypes varies substantially by age, sex, and race/ethnicity (4–7). However, the etiological implications of this biological, clinical, and epidemiological diversity are incompletely understood. The importance of investigating etiology by NHL subtype is clearly supported by research on immunosuppression, infections, and autoimmune diseases, which are the strongest and most e…

AdultMaleCancer ResearchAdolescentChronic lymphocytic leukemiaFollicular lymphomaComorbidityDiseaseNon-Hodgkin lymphoma (NHL)ArticleYoung AdultRisk Factorsimmune system diseasesOccupational Exposurehemic and lymphatic diseasesOdds RatiomedicineCluster AnalysisHumansRisk factorFamily historyLife StyleAgedAged 80 and overInternational Lymphoma Epidemiology Consortium (InterLymph)business.industryLymphoma Non-HodgkinAustraliaCase-control studyGeneral MedicineOdds ratioMiddle Agedmedicine.diseaseLymphomaEuropeOncologyCase-Control StudiesNorth AmericaImmunologyFemalebusinessJNCI Monographs
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Expression of nm23 in gastric carcinoma: association with tumor progression and poor prognosis.

1998

BACKGROUND Expression of nm23 has been shown to be inversely correlated with the metastatic potential of several human cancers. In the current study, the expression and prognostic impact of nm23 was immunohistochemically studied in 413 curatively resected gastric carcinomas. METHODS Tumor sections of the 413 gastric carcinomas were stained with a polyclonal antibody that was raised against the nm23-H1/NDP kinase A, which is identical to the nm23-H1 gene product. RESULTS Expression of nm23 was detected in 84.5% (n = 349) of all tumors, in the majority of cases (71.2%) causing a homogeneous staining reaction in more than 75% of tumor cells. Expression of nm23 was positively correlated with th…

AdultMaleCancer ResearchMetastasisAntigens NeoplasmStomach NeoplasmsLymphatic vesselBiomarkers TumorMedicineHumansLymph nodeAgedMonomeric GTP-Binding ProteinsAged 80 and overbusiness.industryStomachCarcinomaCancerMiddle AgedNM23 Nucleoside Diphosphate Kinasesmedicine.diseasePrognosisSurvival Analysismedicine.anatomical_structureOncologyTumor progressionNucleoside-Diphosphate KinaseCancer researchAdenocarcinomaImmunohistochemistryFemalebusinessCarcinoma Signet Ring CellTranscription FactorsCancer
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Genome-Wide Association Studies of the PR Interval in African Americans.

2011

The PR interval on the electrocardiogram reflects atrial and atrioventricular nodal conduction time. The PR interval is heritable, provides important information about arrhythmia risk, and has been suggested to differ among human races. Genome-wide association (GWA) studies have identified common genetic determinants of the PR interval in individuals of European and Asian ancestry, but there is a general paucity of GWA studies in individuals of African ancestry. We performed GWA studies in African American individuals from four cohorts (n = 6,247) to identify genetic variants associated with PR interval duration. Genotyping was performed using the Affymetrix 6.0 microarray. Imputation was p…

AdultMaleCancer ResearchMuscle ProteinsSingle-nucleotide polymorphismGenome-wide association studyQH426-470030204 cardiovascular system & hematologyBiologyGenetics and Genomics/Complex TraitsPolymorphism Single NucleotideSodium ChannelsWhite PeopleNAV1.5 Voltage-Gated Sodium ChannelNAV1.8 Voltage-Gated Sodium Channel03 medical and health sciencesElectrocardiography0302 clinical medicineAsian PeopleCardiovascular Disorders/Arrhythmias Electrophysiology and PacingGeneticsSNPHumansCardiac and Cardiovascular SystemsPR intervalInternational HapMap ProjectMyeloid Ecotropic Viral Integration Site 1 ProteinMolecular BiologyGenotypingGenetics (clinical)Ecology Evolution Behavior and Systematics030304 developmental biologyAgedGeneticsHomeodomain Proteins0303 health sciencesArrhythmias CardiacHeart-rate;Atherosclerosis risk; Genetic-analysis; Common variants; Design; Populations; Objectives; Conduction; Disease; TwinsMiddle AgedNeoplasm ProteinsMinor allele frequencyBlack or African AmericanAtrioventricular NodeFemaleT-Box Domain ProteinsImputation (genetics)Research ArticleGenome-Wide Association Study
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