Search results for "Meta-analysis"

Meta-analysis of time perception and temporal processing in schizophrenia: Differential effects on precision and accuracy

2016

Numerous studies have reported that time perception and temporal processing are impaired in schizophrenia. In a meta-analytical review, we differentiate between time perception (judgments of time intervals) and basic temporal processing (e.g., judgments of temporal order) as well as between effects on accuracy (deviation of estimates from the veridical value) and precision (variability of judgments). In a meta-regression approach, we also included the specific tasks and the different time interval ranges as covariates. We considered 68 publications of the past 65years, and meta-analyzed data from 957 patients with schizophrenia and 1060 healthy control participants. Independent of tasks and…

Mortality associated with the use of inappropiate drugs according Beers Criteria: a systematic review

2013

The aims of this systematic review are to identify and analyse the scientist literature available evidence about the use of potentially inappropriate medications, according to the Beers Criteria, that is associated with mortality in the elderly people.It have been made a search of publications in most traditional electronic databases among the scientific community (Pubmed / Medline, EMBASE and Web of Science) and it have been selected publications that obey the criteria of 'observational study', 'elderly' and 'Beers Criteria' and that they had as a result the mortality of the study population. After publications selection it proceeded to dump data by two researchers independently to avoid s…

Flawed Meta-Analysis of Biodiversity Effects of Forest Management

2010

It appears that the negative effect of forest managementon biodiversity has become an axiom. Whether the neg-ative effect, however, is a fact based on solid empiricalevidence is not self-evident. Most of the studies that ad-dress the issue suffer from a lack of geographic extentand taxonomic narrowness. Therefore, a synthesis draw-ing together results from the individual studies is direlyneeded. In their recent paper, Paillet et al. (2010) rise tothis challenge and present a formal pan-European meta-analysis of data from 49 papers representing 120 indi-vidual comparisons across 10 taxonomic groups. Theirsynthesis has the potential to be a landmark paper inecological research, but also to af…

Effects of the Best Possible Self intervention: A systematic review and meta-analysis

2019

The Best Possible Self (BPS) exercise promotes a positive view of oneself in the best possible future, after working hard towards it. Since the first work that attempted to examine the benefits of this intervention in 2001, studies on the BPS have grown exponentially and, currently, this is one of the most widely used Positive Psychology Interventions. However, little is yet known about its overall effectiveness in increasing wellbeing outcomes. Thus, the aim of this meta-analysis is to shed light on this question. A systematic literature search was conducted, and 29 studies (in 26 articles) met the inclusion criteria of empirically testing the intervention and comparing it to a control con…

Meta-analysis of the relationship between teachers’ self-efficacy and attitudes toward inclusive education

2022

Abstract This meta-study aims to examine the size of the relationship between teachers' self-efficacy and attitudes toward inclusive education of K-12 students with special educational needs and to identify potential moderators (publication, sample, and research procedure characteristics). We synthesized the research conducted from 1994 to 2018, and 41 studies were included. Bare-bones meta-analysis with random effect model revealed a sample size weighted correlation coefficient between teachers’ self-efficacy and attitudes as r ¯  = 0.35 (CI = 0.31-0.39). The between-study variations were not associated with hypothesized publication and sample characteristics. However, the self-efficacy me…

Microplastics and the functional traits of fishes: A global meta‐analysis

2021

Over the years, concern about the effects of microplastics has grown. Here, we answered the main question “What are the impacts of microplastics on the functional traits of fish species?” through a meta-analysis. The general impact of microplastic exposure on the functional traits of fishes and specifically on eight variables, namely, behaviour, development, fecundity, feeding, growth, health, hatching and survival was explored. Subgroup analyses were performed to detect correlations between the impact of microplastics and the following factors: species, life stage, habitat, water column habitat, day of exposure to microplastics and microplastic size, type and shape. A meta-regression analy…

Effects of Ocean Acidification on physiology, behaviour and ecology of fish

CO2 concentration in the atmosphere is increasing at unprecedented rate since the last 800,000 years due to rising fossil fuel combustion, industrial processes and land use by humans. By absorbing part of this gas from the atmosphere, Oceans contribute to the mitigation of climatic changes, but at the cost of greater modifications of their physical and chemical characteristics. CO2 dissolved in the seawater leads to increased bicarbonate (HCO3 -) and hydrogen ions (H+) concentrations with a consequent pH drop, a phenomenon known as Ocean Acidification (OA). If global policy will not put in force mitigation measures to reduce CO2 emissions, it is projected that partial pressure of dissolved …

Systematic review by meta-analyses on the possible role of TNF-alpha polymorphisms in association with Alzheimer's disease.

2009

It has been hypothesized that polymorphisms of Tumor Necrosis Factor (TNF)-alpha gene affect the risk of developing Alzheimer's disease (AD). However, results of different studies are often inconsistent. Our aim was to investigate by meta-analysis the association of the common polymorphisms comprehensively defining the genetic variability of the TNF-alpha gene with AD risk. Hence, the results being stated are of a meta-analysis across studies, and that this meta-analysis does not invalidate the results of the individual studies previously performed. Seventeen studies that investigated the association between 5 TNF-alpha polymorphisms (-850, -308, -863, -238, and -1031) and AD were retrieved…

Efficacy and safety of γδT cell-based tumor immunotherapy: a meta-analysis.

2014

Vγ9Vδ2 T cells are important effector cells that may play a role in the anti-tumor immune response. Their capability to exert MHC-nonrestricted lytic activity against different tumor cells in vitro and their detection among tumor infiltrating lymphocytes in a variety of human cancers have supported the development of Vγ9Vδ2 T cell-based immunotherapy in the context of novel treatment against cancer. Accordingly, promising reports from recent clinical trials support the use of V γ9Vδ2 T cells as immunotherapeutic agents, either via adoptive transfer of ex-vivo expanded V γ9Vδ2 T cells or in vivo activation of V γ9Vδ2 T cells with compounds such as phosphoantigens or aminobisphosphonates. In …

The prognostic role of KRAS and BRAF in patients undergoing surgical resection of colorectal cancer liver metastasis: a systematic review and meta-an…

2016

Background: Clinical trials investigated the potential role of both KRAS and BRAF mutations, as prognostic biomarkers, in colorectal cancer (CRC) patients who underwent surgical treatment of liver metastasis (CLM), showing conflicting results. This meta-analysis aims to review all the studies reporting survival outcomes (recurrence free survival (RFS), and/or overall survival (OS)) of patients undergoing resection of CLM, stratified according to KRAS and/or BRAF mutation status. Materials and Methods: Data from all published studies reporting survival outcomes (RFS and/or OS) of CRC patients who received resection of CLM, stratified by KRAS and/or BRAF mutation status were collected by sear…