Search results for "Metabolic"
showing 10 items of 2205 documents
Alterazioni emoreologiche nella sindrome metabolica
2015
La sindrome metabolica (SM) si accompagna ad un elevato rischio cardiovascolare. Oltre ai tradizionali fattori di rischio, dei quali la SM rappresenta un’aggregazione, sono identificabili fattori non tradizionali quali l’assetto emoreologico. È noto da tempo che un disordine emoreologico si accompagna alla SM, ed è ipotizzabile una sua influenza sui meccanismi che instaurano e mantengono l’insulino-resistenza. In un gruppo di pazienti con SM abbiamo osservato un incremento della viscosità ematica e plasmatica e una riduzione della filtrabilità ematica. Il rapporto vita-fianchi, indice di obesità addominale, era direttamente correlato con la viscosità ematica e con l’ematocrito, mentre la vi…
Adaptations in body composition, metabolic health and physical fitness during strength or endurance training or their combination in healthy middle-a…
2011
Different-day and same-session combined strength and endurance training : adaptations in neuromuscular and cardiorespiratory performance, body compos…
2017
This thesis investigated 1) acute neuromuscular and hormonal responses to combined strength and endurance loadings with different orders and their long-term adaptations (women), 2) adaptations in neuromuscular, hormonal, cardiorespiratory and health variables following 24 weeks of volume-equated protocols of combined training (men and women). Subjects were assigned to one of three groups: strength and endurance training on different days (DD: men n=21, women n=18), training in the same-session with either endurance before strength (ES: men n=16, women n=15) or vice versa (SE: men n=18, women n=14). DD trained 4-6 d·wk-1 with strength and endurance on alternating days. ES and SE trained 2-3 …
The relationship between context, structure, and processes with outcomes of 6 regional diabetes networks in Europe
2018
BackgroundWhile health service provisioning for the chronic condition Type 2 Diabetes (T2D) often involves a network of organisations and professionals, most evidence on the relationships between the structures and processes of service provisioning and the outcomes considers single organisations or solo practitioners. Extending Donabedian's Structure-Process-Outcome (SPO) model, we investigate how differences in quality of life, effective coverage of diabetes, and service satisfaction are associated with differences in the structures, processes, and context of T2D services in six regions in Finland, Germany, Greece, Netherlands, Spain, and UK.MethodsData collection consisted of: a) systemat…
Longitudinal and cross-sectional associations of adherence to 24-hour movement guidelines with cardiometabolic risk
2022
This study aimed to examine 1) adherence to 24-hour movement guidelines over a 2-year follow-up in children aged 6-8 years and 2) association of this adherence with cardiometabolic risk factors. Physical activity and sleep were assessed by a monitor combining heart rate and accelerometry measurements. Screen time was reported by the parents. Body fat percentage, waist circumference, blood glucose, serum insulin, plasma lipids and blood pressure were assessed, and a cardiometabolic risk score was calculated using z-scores. Children were classified as meeting the guidelines if they had on average ≥60min/day of moderate-to-vigorous physical activity during the valid days; ≤120min/day of screen…
Metabolic Reprogramming of Innate Immune Cells as a Possible Source of New Therapeutic Approaches in Autoimmunity.
2022
Immune cells undergo different metabolic pathways or immunometabolisms to interact with various antigens. Immunometabolism links immunological and metabolic processes and is critical for innate and adaptive immunity. Although metabolic reprogramming is necessary for cell differentiation and proliferation, it may mediate the imbalance of immune homeostasis, leading to the pathogenesis and development of some diseases, such as autoimmune diseases. Here, we discuss the effects of metabolic changes in autoimmune diseases, exerted by the leading actors of innate immunity, and their role in autoimmunity pathogenesis, suggesting many immunotherapeutic approaches.
Identification of omic profiles for diagnosis and monitoring of bladder cancer
2019
La presente Tesis titulada Identificación de perfiles ómicos para el diagnóstico y la monitorización del cáncer de vejiga se centra en la identificación de biomarcadores metabolómicos urinarios no invasivos para el diagnóstico y la monitorización del cáncer de vejiga (CaV). Con este fin, se han utilizado dos plataformas analíticas: la Resonancia Magnética Nuclear (Nuclear Magnetic Resonance, 1H NMR) y la Cromatografía Líquida de alta resolución acoplada a la Espectrometría de Masas (Ultraperformance Liquid Chromatography–Mass Spectrometry, UPLC-MS). Además, se han analizado tejidos vesicales mediante la técnica de Resonancia Magnética Nuclear de Alta Resolución con Giro de Ángulo Mágico (Hi…
Alternative measures of body composition and wage premium: New evidence from Indonesia
2019
This paper examines the relationship between body composition and earnings in a developing country setting. We use body mass index, waist circumference and hip circumference. Exploiting the panel structure of our longitudinal survey, we find that along with BMI, waist circumference is related to higher earnings in Indonesia. peerReviewed
Uni ja kardiometabolia : vaihdevuosi-ikäisten naisten unen laadun yhteys sokeri- ja rasva-aineenvaihduntaan ja leptiinitasoihin
2017
Unen laatu heikkenee vaihdevuosien aikana. Heikentynyt unen laatu on yhteydessä sokeri- ja rasva-aineenvaihdunnan häiriöihin. Tämän pro gradu-tutkielman tarkoituksena oli selvittää vaihdevuosi-ikäisten naisten unen laadun yhteyttä kardiometabolisiin riskitekijöihin. Tutkielma perustuu Estrogeeni, vaihdevuodet ja toimintakyky (ERMA) -tutkimuksen aineistoon. Osallistujat poimittiin satunnaisotannalla väestörekisteristä Jyväskylän ja sen lähikuntien 47–54 -vuotiaista naisista (n=6886). Mukaan valittiin ne sisäänottokriteerit täyttävät naiset, jotka vastasivat tutkimuksen alkumittauskyselyyn ja joilta terveydentilaa selvittävän haastattelun sekä laboratoriomittausten jälkeen saatiin luotettavas…
Uztura paradumu, fiziskās aktivitātes un miera vielmaiņas intensitātes izvērtējums jaunu cilvēku grupā
2016
Liekais svars un aptaukošanās pazemina dzīves kvalitāti un ir par iemeslu daudzām saslimšanām: diabētam, koronārajām sirds slimībām, onkoloģiskajām saslimšanām, metabolajam sindromam. Pētījuma mērķis ir izvērtēt uztura, fiziskās aktivitātes (FA) un miera vielmaiņas intensitātes (RMR) korelāciju ar ķermeņa tauku masu jaunu, pieaugušu, klīniski veselu cilvēku grupā. Pētījuma gaitā tika analizēta izmeklējamo personu 3 dienu uztura dienasgrāmata, fiziskā aktivitāte noteikta ar anketēšanas metodi, veikti antropometriskie mērījumi un reģistrēta miera vielmaiņas intensitāte ar netiešās kalorimetrijas metodi. Pētījuma rezultātā tika secināts, ka respondentu uzturā ir samazināts relatīvais ogļhidrāt…