Search results for "Metaphase"

showing 10 items of 35 documents

Karyotype analyses reveal inter-individual polymorphism and association of nucleolus-organizer-carrying chromosomes in Capros aper (Pisces: Zeiformes)

1992

Three different karyomorphs with 2n=46, 2n=44 and 2n=42 for Capros aper (L., 1758) (Zeiformes) collected from the Gulf of Lion, near Banyuls-sur-Mer, France, in July 1990 were determined. Karyomorphs were characterized by the same arm number [Fundamental number (FN)=50], suggesting that chromosome variations are due to Robertsonian fusions. In somatic metaphase spreads stained with silver nitrate, nucleolus organizer regions (NORs) consistently occupied a terminal position on the short arms of two small submetacentric chromosomes. Ca. 30% of silver-stained metaphases in each specimen showed NOR chromosomes associated in pairs by their nucleolus organizer regions.

GeneticsEcologybiologyNucleolusChromosomeKaryotypeAquatic Sciencebiology.organism_classificationZeiformesEvolutionary biologyShort armsPolymorphism (computer science)Nucleolus organizer regionMetaphaseEcology Evolution Behavior and SystematicsMarine Biology
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Microsporogenesis in three wild species of the genusAntirrhinumL. (A. litigiosumPau,A. pulverulenthumLazaro andA. subbaeticumGüemes, Sánchez and Mate…

2010

The diploid chromosome number (2n = 2x = 16) in three wild species A. litigiosum Pau, A. pul- verulenthum Lazaro and A. subbaeticum Guemes, Sanchez & Mateu, belonging to the genus Antirrhinum was cytologically observed. Genetic stability of the simultaneous meiotic division type was found in these natural growing snapdragons. The synchronicity at the initial meiotic stages and at tetrad and pollen creation was high and disappeared with the diakinesis initiation. Refl ecting the systematic position of the studied species into Antirrhinum, the performed investigation mani- fested similarity: in the presence of univalents and quadrivalent confi gurations parallel with bivalents at the early me…

GeneticsfungiAntirrhinumChromosomeBiologymedicine.disease_causebiology.organism_classificationBivalent (genetics)ChiasmaMeiosisPollenBotanyGeneticsmedicinePloidyGeneral Agricultural and Biological SciencesMetaphaseCaryologia
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High resolution analysis and differential condensation in RBA-banded human chromosomes.

1981

Human prophase, premetaphase, and mid-metaphase chromosomes are prepared and analyzed using the thymidine cell synchronization technique and R-banding patterns (RBA). Haploid sets with 700–1000 bands can be demonstrated. Sequences of chromosomes of different degrees of condensation are helpful for a better understanding and classification of regions of extended chromosomes. A considerable variation in the condensation of parts of homologous chromosomes is reflected in the variability of the arm ratio. This differential condensation of chromosomes is entirely effected by variation of the degree of condensation in AT rich interbands and can be attributed to the degree of labeling by BrdU.

High resolution analysisGeneticsCondensationCytological TechniquesGenetic VariationBiologyProphaseAcridine OrangeChromosome BandingProphaseBromodeoxyuridineGeneticsHomologous chromosomeBiophysicsChromosomes HumanHumansPloidyCell synchronizationGenetics (clinical)MetaphaseHuman genetics
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Microtubule organization and distribution of gamma-tubulin in male meiosis of lepidoptera

1996

Meiotic spindles in males of higher Lepidotera are unusual in that the bulk of the spindle micro-tubules (MTs) ends about halfway between the equatorial plate and the centrosomes in metaphase. It appears worthwhile to determine how the MTs are nucleated, while their pole proximal ends are distant from the centrosomes. To this end, spermatocytes of Phragmatobia fuliginosa (Arctiidae), collected in the field, were double-labeled with antibodies to beta- and gamma-tubulin. The former antibody reveals the entire microtubular cytoskeleton, and the latter is directed against a newly-discovered tublin isoform that is prevalent in microtubule-organizing centers (MTOCs). The immunocytochemical work …

Kinetochoremacromolecular substancesCell BiologySpermatocyteAnatomyBiologySpindle pole bodyCell biologySpindle apparatusmedicine.anatomical_structureMicrotubuleGeneticsmedicinePrometaphaseMetaphaseDevelopmental BiologyAnaphaseMolecular Reproduction and Development
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Mapping genomic rearrangements in titi monkeys by chromosome flow sorting and multidirectional in-situ hybridization.

2004

We developed chromosome painting probes for Callicebus pallescens from flow-sorted chromosomes and used multidirectional chromosome painting to investigate the genomic rearrangements in C. cupreus and C. pallescens. Multidirectional painting provides information about chromosomal homologies at the subchromosomal level and rearrangement break points, allowing chromosomes to be used as cladistic markers. Chromosome paints of C. pallescens were hybridized to human metaphases and 43 signals were detected. Then, both human and C. pallescens probes were hybridized to the chromosomes of another titi monkey, C. cupreus. The human chromosome paints detected 45 segments in the haploid karyotype of C.…

Lineage (genetic)TitiSyntenyChromosome PaintingEvolution MolecularGeneticsAnimalsHumansIn Situ Hybridization FluorescenceMetaphaseSyntenyComparative genomicsGeneticsGene RearrangementGenomebiologyChromosomeChromosome MappingKaryotypeCallicebus pallescensbiology.organism_classificationFlow CytometryChromosomes MammalianDiploidyCebidaeKaryotypingPloidyDNA ProbesChromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology
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Starfish and Xenopus oocyte maturation

2007

Treatment with heavy metals, such as nickel, lead or cadmium, elicits different cellular stress responses according to the metal used and the length of treatment. In Paracentrotus lividus embryos the inducible forms of HSP70 (HSP70/72) are different in molecular mass from the constitutively expressed HSP75, and they can be used as markers of cellular stress. Even a short treatment with each metal induces the synthesis of HSP70/72 which remain stable for at least 20h and differ little in their isoelectric points. Continuous treatment from fertilization with nickel or lead produces late irregular pluteus embryos, with peak HSP70/72 synthesis at blastula followed by the arrest of synthesis by …

MAPK/ERK pathwaymedicine.medical_specialtyOocytebiologyurogenital systemG proteinMetaphase iiStarfishXenopusbiology.organism_classificationOocyteCell biologyEndocrinologymedicine.anatomical_structureCytostatic factorInternal medicinemedicineAnimal Science and ZoologyMaturation process
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Intracellular activation of ovastacin mediates pre-fertilization hardening of the zona pellucida

2017

Study question How and where is pro-ovastacin activated and how does active ovastacin regulate zona pellucida hardening (ZPH) and successful fertilization? Study finding Ovastacin is partially active before exocytosis and pre-hardens the zona pellucida (ZP) before fertilization. What is known already The metalloproteinase ovastacin is stored in cortical granules, it cleaves zona pellucida protein 2 (ZP2) upon fertilization and thereby destroys the ZP sperm ligand and triggers ZPH. Female mice deficient in the extracellular circulating ovastacin-inhibitor fetuin-B are infertile due to pre-mature ZPH. Study design, samples/materials, methods We isolated oocytes from wild-type and ovastacin-de…

Male0301 basic medicineEmbryologyPrimary Cell CultureFertilization in VitroBiologyCleavage (embryo)Zona Pellucida GlycoproteinsExocytosisExocytosisMice03 medical and health sciences0302 clinical medicineHuman fertilizationGeneticsmedicineAnimalsChymotrypsinZona pellucidaMolecular BiologyMetaphaseZona PellucidaOriginal Research030219 obstetrics & reproductive medicineGene Expression Regulation DevelopmentalObstetrics and GynecologyOocyte activationEmbryoCell BiologyPolyspermySpermatozoaSpermFetuin-BCell biology030104 developmental biologymedicine.anatomical_structureReproductive MedicineProteolysisMetalloproteasesOocytesFemaleSignal TransductionDevelopmental Biology
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Meiosis in translocation heterozygotes in the mosquito Culex pipiens.

1971

Adult Culex pipiens males irradiated with both X-rays and neutrons were crossed to untreated females and F1-egg rafts were checked for dominant lethality. F1-progenies were outcrossed with normal individuals in order to obtain lines with inherited semisterility. From a total of 120 lines that showed a certain amount of sterility 12 lines were studied cytologically. 10 lines showed reciprocal chromosome exchanges.—At late pachytene and diplotene cross configurations with large asynaptic regions at the center of the cross are obligatory. Bivalents, chains of three, chains of four, and ring configurations are present at metaphase and anaphase I. The different frequencies of the occurrence of s…

MaleHeterozygoteBiometryMitosisInterference (genetic)ChromosomesMeiosisCulex pipiensCentromereGeneticsAnimalsCrossing Over GeneticMetaphaseGenetics (clinical)Crosses GeneticAnaphaseGenes DominantGeneticsChromosome AberrationsNeutronsbiologyChromosomebiology.organism_classificationChiasmaRadiation EffectsCulexMeiosisInfertilityFemaleGenes LethalChromosoma
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A high incidence of meiotic silencing of unsynapsed chromatin is not associated with substantial pachytene loss in heterozygous male mice carrying mu…

2009

Meiosis is a complex type of cell division that involves homologous chromosome pairing, synapsis, recombination, and segregation. When any of these processes is altered, cellular checkpoints arrest meiosis progression and induce cell elimination. Meiotic impairment is particularly frequent in organisms bearing chromosomal translocations. When chromosomal translocations appear in heterozygosis, the chromosomes involved may not correctly complete synapsis, recombination, and/or segregation, thus promoting the activation of checkpoints that lead to the death of the meiocytes. In mammals and other organisms, the unsynapsed chromosomal regions are subject to a process called meiotic silencing of…

MaleHeterozygoteCancer ResearchDevelopmental Biology/Germ Cellslcsh:QH426-470BiologíaCell Biology/Cell Growth and DivisionChromosomal translocationMeiocyteBiologyTranslocation GeneticMiceMeiosisSpermatocytesGeneticsHomologous chromosomeAnimalsGene SilencingMolecular BiologyMetaphaseGenetics (clinical)Ecology Evolution Behavior and SystematicsGeneticsSex ChromosomesAutosomeSynapsisChromosomeSynapsisChromatinGenetics and Genomics/Chromosome BiologyChromosome PairingMeiosislcsh:GeneticsEvolutionary Biology/Nuclear Structure and FunctionFemalePachytene StageResearch ArticlePLoS Genetics
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Virus-like particles, bacteria and microsporidia affect spindle-associated membranes in spermatocytes of Lepidoptera species.

1997

SummaryLarval testes of four Lepidoptera species were examined using electron microscopy. The testes of one species, the Mediterranean mealmothEphestia kuehniella(Pyralidae), were devoid of intracellular pathogens and serve as a control. In this species, metaphase spindles of primary spermatocytes showed a thick layer of perispindle membranes. The membranes were structurally very similar to the agranular endoplasmic reticulum. Membranes of this type occurred also at high frequency throughout the spindle matrix. The analysis of larval testes ofPieris brassicae(Pieridae) revealed virus-like particles within spermatocytes. In another species,Philudoria potatoria(Lasiocampidae), the spermatocyt…

MalePieris brassicaebiologyBacteriaMicrosporidaVirionCell BiologySpindle matrixIntracellular MembranesSpindle ApparatusMothsbiology.organism_classificationCell biologyLepidoptera genitaliaMicroscopy ElectronMembraneMeiosisSpermatocytesMicrosporidiaBotanyTestisAnimalsSpermatogenesisMetaphaseDevelopmental BiologyZygote (Cambridge, England)
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