Search results for "Method"

showing 10 items of 13253 documents

A novel solution based on scale invariant feature transform descriptors and deep learning for the detection of suspicious regions in mammogram images.

2020

Background: Deep learning methods have become popular for their high-performance rate in the classification and detection of events in computer vision tasks. Transfer learning paradigm is widely adopted to apply pretrained convolutional neural network (CNN) on medical domains overcoming the problem of the scarcity of public datasets. Some investigations to assess transfer learning knowledge inference abilities in the context of mammogram screening and possible combinations with unsupervised techniques are in progress. Methods: We propose a novel technique for the detection of suspicious regions in mammograms that consist of the combination of two approaches based on scale invariant feature …

lcsh:Medical technologyclassificationlcsh:R855-855.5computer-assisted image processingdigital mammographydeep learningOriginal Articlecomputing methodologiesClassification computer‐assisted image processing computing methodologies deep learning digital mammography
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Characteristics of clinical trials in rare vs. common diseases: A register-based Latvian study.

2017

Background Conducting clinical studies in small populations may be very challenging; therefore quality of clinical evidence may differ between rare and non-rare disease therapies. Objective This register-based study aims to evaluate the characteristics of clinical trials in rare diseases conducted in Latvia and compare them with clinical trials in more common conditions. Methods The EU Clinical Trials Register (clinicaltrialsregister.eu) was used to identify interventional clinical trials related to rare diseases (n = 51) and to compose a control group of clinical trials in non-rare diseases (n = 102) for further comparison of the trial characteristics. Results We found no significant diffe…

lcsh:MedicineDiseaseGeographical locationslaw.invention0302 clinical medicineRandomized controlled triallawOutcome Assessment Health CareClinical endpointMedicine and Health SciencesRegistrieslcsh:ScienceClinical Trials as TopicMultidisciplinaryDrug MarketingPhase III clinical investigationSurvival RateEuropeOncology030220 oncology & carcinogenesisMeta-analysisComparatorsEngineering and TechnologyPhase II clinical investigationResearch Articlemedicine.medical_specialtyRandomizationDrug Research and DevelopmentResearch and Analysis Methods03 medical and health sciencesRare DiseasesInternal medicinemedicineHumansClinical TrialsEuropean UnionSurvival ratePharmacologybusiness.industrylcsh:RLatviaRandomized Controlled TrialsClinical triallcsh:QClinical MedicinePeople and placesElectronicsbusiness030217 neurology & neurosurgeryRare diseasePloS one
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A web-based collection of genotype-phenotype associations in hereditary recurrent fevers from the Eurofever registry

2017

PubMed ID: 29047407

lcsh:MedicineFamilial Mediterranean feverCaps; Eurofever; FMF; Genotype-phenotype associations; Hereditary recurrent fevers; Infevers; MKD; Traps; Databases Genetic; Europe; Hereditary Autoinflammatory Diseases; Humans; Retrospective Studies; Genetic Association Studies; Registries0302 clinical medicineHereditary recurrent feverInfeversDatabases GeneticPharmacology (medical)030212 general & internal medicineRegistriesGenetics (clinical)EurofeverGeneral MedicineMEFVResponse to treatmentCapHereditary recurrent fevers3. Good healthGenotype-phenotype associationTrapEuropeComputingMilieux_MANAGEMENTOFCOMPUTINGANDINFORMATIONSYSTEMSInformationSystems_MISCELLANEOUSInflammatory diseases Radboud Institute for Molecular Life Sciences [Radboudumc 5]medicine.medical_specialtyGenotype-Phenotype AssociationInfever03 medical and health sciencesDatabasesFMFGeneticInternal medicineJournal ArticlemedicineHumansHereditary Recurrent FeversIn patientMKDTrapsGenetic Association StudiesRetrospective Studies030203 arthritis & rheumatologyGenotype-phenotype associationsbusiness.industryResearchlcsh:RComputerSystemsOrganization_COMPUTER-COMMUNICATIONNETWORKSHereditary Autoinflammatory DiseasesRetrospective cohort studymedicine.diseaseHuman geneticsComputingMethodologies_PATTERNRECOGNITIONCapsbusinessCaps; Eurofever; FMF; Genotype-phenotype associations; Hereditary recurrent fevers; Infevers; MKD; Traps; Genetics (clinical); Pharmacology (medical)
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The Value of Median Nerve Sonography as a Predictor for Short- and Long-Term Clinical Outcomes in Patients with Carpal Tunnel Syndrome: A Prospective…

2016

Objectives To investigate the prognostic value of B-mode and Power Doppler (PD) ultrasound of the median nerve for the short- and long-term clinical outcomes of patients with carpal tunnel syndrome (CTS). Methods Prospective study of 135 patients with suspected CTS seen 3 times: at baseline, then at short-term (3 months) and long-term (15–36 months) follow-up. At baseline, the cross-sectional area (CSA) of the median nerve was measured with ultrasound at 4 levels on the forearm and wrist. PD signals were graded semi-quantitatively (0–3). Clinical outcomes were evaluated at each visit with the Boston Questionnaire (BQ) and the DASH Questionnaire, as well as visual analogue scales for the pat…

lcsh:MedicineHandsWristNervous SystemDiagnostic Radiology0302 clinical medicineUltrasound ImagingMedicine and Health SciencesCarpal tunnellcsh:ScienceProspective cohort studyMusculoskeletal SystemMultidisciplinaryRadiology and ImagingMuscle AnalysisWristArmsmedicine.anatomical_structureBioassays and Physiological AnalysisAnatomyMuscle ElectrophysiologyResearch Articlemedicine.medical_specialtyImaging TechniquesCarpal tunnel surgerySurgical and Invasive Medical ProceduresResearch and Analysis Methods03 medical and health sciencesForearmDiagnostic MedicineDashmedicinePain ManagementCarpal tunnel syndrome030203 arthritis & rheumatologybusiness.industrylcsh:RLimbs (Anatomy)Electrophysiological TechniquesBiology and Life SciencesMyalgiamedicine.diseaseMedian nerveSurgerynervous system diseasesNeuroanatomylcsh:Qbusiness030217 neurology & neurosurgeryNeurosciencePLoS ONE
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Mismatch negativity (MMN) in freely-moving rats with several experimental controls.

2014

Mismatch negativity (MMN) is a scalp-recorded electrical potential that occurs in humans in response to an auditory stimulus that defies previously established patterns of regularity. MMN amplitude is reduced in people with schizophrenia. In this study, we aimed to develop a robust and replicable rat model of MMN, as a platform for a more thorough understanding of the neurobiology underlying MMN. One of the major concerns for animal models of MMN is whether the rodent brain is capable of producing a human-like MMN, which is not a consequence of neural adaptation to repetitive stimuli. We therefore tested several methods that have been used to control for adaptation and differential exogenou…

lcsh:MedicineMismatch negativityNeurophysiologyBiologyStimulus (physiology)ElectroencephalographyAuditory cortexResearch and Analysis Methodsbehavioral disciplines and activitiesModel OrganismsEvent-related potentialmedicineAnimalsHumanslcsh:ScienceOddball paradigmta515Auditory CortexBrain MappingMultidisciplinarymedicine.diagnostic_testlcsh:RNeural adaptationSkullBiology and Life SciencesElectroencephalographyAnimal ModelsSensory SystemsFrontal LobeRatsmedicine.anatomical_structureFrontal lobeAcoustic StimulationBrain ElectrophysiologyAuditory SystemModels AnimalEvoked Potentials Auditorylcsh:QNeuroscienceResearch ArticleNeurosciencePloS one
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All-Possible-Couplings Approach to Measuring Probabilistic Context.

2013

From behavioral sciences to biology to quantum mechanics, one encounters situations where (i) a system outputs several random variables in response to several inputs, (ii) for each of these responses only some of the inputs may "directly" influence them, but (iii) other inputs provide a "context" for this response by influencing its probabilistic relations to other responses. These contextual influences are very different, say, in classical kinetic theory and in the entanglement paradigm of quantum mechanics, which are traditionally interpreted as representing different forms of physical determinism. One can mathematically construct systems with other types of contextuality, whether or not …

lcsh:MedicineQuantum entanglementSocial and Behavioral Sciences01 natural sciencesQuantitative Biology - Quantitative MethodsJoint probability distributionPsychologyStatistical physicslcsh:ScienceQuantumQuantitative Methods (q-bio.QM)60B99 (Primary) 81Q99 91E45 (Secondary)PhysicsQuantum PhysicsMultidisciplinaryApplied MathematicsPhysics05 social sciencesComplex SystemsMental HealthMedicineMathematics - ProbabilityAlgorithmsResearch ArticleFOS: Physical sciencesContext (language use)Physical determinism050105 experimental psychologyProbability theory0103 physical sciencesFOS: Mathematics0501 psychology and cognitive sciences010306 general physicsQuantum MechanicsProbabilityta113BehaviorModels Statisticallcsh:RProbability (math.PR)Probabilistic logicRandom VariablesProbability TheoryKochen–Specker theoremFOS: Biological sciencesQuantum Theorylcsh:QQuantum EntanglementQuantum Physics (quant-ph)Mathematics
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Spectral characteristics of 5-hydroxymethylfurfural as a related substance in medicinal products containing glucose

2019

Objectives: To study 5-hydroxymethylfurfural (5-HMF) spectral characteristics aiming at their future application in analytical procedures and their validation for the determination of 5-HMF in liquid products containing glucose after sterilization.Method: Direct spectrophotometric method for the determination of 5-HMF using the molar absorption coefficient at the absorption maximum (284 nm).Results and discussion: aqueous 5-HMF solutions have strong absorption in the ultraviolet range below 310 nm and give two absorption maxima at wavelengths of 229–230 nm and 284 nm. An excellent linear relationship between absorbance and 5-HMF concentration was observed in the concentration range of 2.0–1…

lcsh:Pharmacy and materia medica5-hydroxymethylfurfuralChemistry5-hydroxymethylfurfurallcsh:RS1-441medicinal products containing glucosePharmaceutical Sciencemolar absorption coefficientPharmacology (medical)PharmacyFood sciencespectrophotometric methodPharmacia
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La competencia textual y mediática en el aula de ELE

2017

Resumen: La habilidad de comprender y producir textos es una de las competencias basicas en la sociedad de la informacion y de la comunicacion (OECD, 2000). Sin embargo, el concepto texto ha evolucionado adquiriendo una versatilidad que rebasa la concepcion tradicional de texto escrito. Para superar este desfase al que la competencia lectora o las destrezas en la comprension y/o expresion oral no llegan, se propone desde Alemania el termino competencia textual y mediatica [1] . La finalidad de esta comunicacion es reflexionar sobre la importancia de esta nueva competencia y dotar al profesorado de herramientas en el tratamiento de la competencia textual en el aula de ELE. Para ello, present…

lcsh:Philology. Linguisticslcsh:P1-1091ComputingMethodologies_DOCUMENTANDTEXTPROCESSING:PEDAGOGÍA [UNESCO]lcsh:LUNESCO::PEDAGOGÍAlcsh:Education
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The relation between human values and perceived situation characteristics in everyday life

2018

Values refer to abstract beliefs which serve as guidelines in peoples’ life and affect the way people and events are evaluated. Simultaneously, unlike attitudes, values transcend specific actions, and situations. While recent research showed that values are related to the attention and interpretation of situational information in standardized laboratory settings, up to date hardly any empirical work investigated how values relate to situation perception in daily life. In our study, we assessed the relation between the endorsement of human values and situation characteristics (i.e., the 8 DIAMONDS). Using the Day Reconstruction Method in two samples (German and US-American), we found that es…

lcsh:PsychologyDDC 150 / PsychologyWertddc:150lcsh:BF1-990Wertorientierunghuman valuesdaily lifeValuessituation perception8 DIAMONDSday reconstruction method
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La innovación educativa desde la metodología: Mejora de las actitudes y competencias científicas de los alumnos (Educational innovation in research m…

2010

A programme of educational innovation was implemented to improve the attitude toward research methods for psychology students. Students used real data to test their own hypotheses using different statistical methods. Specifically, they implemented two key methodological principles in research methods: sample size and ordinal claims (Frick, 1996). Students had to work in teams, using Internet data bases for developing the theoretical background of the study, the definition of the objectives, the definition of variables, data analysis, and discussion of results. We assessed the attitudes towards research methods before and after the study. Results showed that: 1) the students improved their s…

lcsh:Psychologylcsh:Blcsh:BF1-990MethodologyAttitudes toward methodologyEducational innovationlcsh:Philosophy. Psychology. ReligionEscritos de Psicología
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