Search results for "Metrizamide"
showing 2 items of 2 documents
Myelography: current status and post-marketing experience with iotrolan
1995
There are three imaging modalities for the diagnosis of spinal diseases: magnetic resonance imaging (MRI), computed tomography (CT) and myelography. The choice of modality is influenced by factors including diagnostic accuracy cost, radiation dose and invasiveness. For many indications, MRI has advantages over CT and myelography and is the modality of choice, and there is likely to be a trend away from myelographic examinations. In cases where myelography is indicated, it is of prime importance to reduce the frequency and severity of adverse events. During phase III and IV trials, involving over 2000 patients, general and neural tolerance of iotrolan was shown to be significantly better tha…
Microscopic Endonasal Surgery for Repair of CSF Leaks
1993
This manuscript will detail our experience using a microscopic endonasal surgery (MES) approach in the repair of spontaneous, traumatic, and/or iatrogenic cerebrospinal fluid (CSF) fistula into the ethmoid and sphenoid sinuses. The location of the fistula in 22 patients was determined by a direct endoscopic or microscopic visualization, intrathecal fluorescein, or computed tomography (CT) with metrizamide. Several of these patients had been treated unsuccessfully with previous neurosurgical, intracranial, and extracranial approaches to stop the leak. The CSF fistulas in all these patients were repaired with a MES approach, packing the leak with either a septal mucosal graft, or abdominal f…