Search results for "MgV"

showing 2 items of 2 documents

Comparing analytical methods to detect SARS-CoV-2 in wastewater

2021

Wastewater based epidemiology (WBE) has emerged as a reliable strategy to assess the coronavirus disease 2019 (COVID-19) pandemic. Recent publications suggest that SARS-CoV-2 detection in wastewater is technically feasible; however, many different protocols are available and most of the methods applied have not been properly validated. To this end, different procedures to concentrate and extract inactivated SARS-CoV-2 and surrogates were initially evaluated. Urban wastewater seeded with gamma-irradiated SARS-CoV-2, porcine epidemic diarrhea virus (PEDV), and mengovirus (MgV) was used to test the concentration efficiency of an aluminum-based adsorption-precipitation method and a polyethylene…

Environmental Engineering010504 meteorology & atmospheric sciencesSwineMicrobiologiaWastewater010501 environmental sciences01 natural sciencesArticleWHO World Health OrganizationAigües residuals MicrobiologiaAluminum-based adsorption-precipitationSpin column-based nucleic acid purificationPEG ratioAnimalsHumansEnvironmental ChemistryPandemicsWaste Management and DisposalPEG polyethylene glycol0105 earth and related environmental sciencesDetection limitCOVID-19 Coronavirus disease 2019ChromatographybiologySARS-CoV-2MgV MengovirusWBE wastewater-based epidemiologyChemistryPorcine epidemic diarrhea virusRT-qPCRExtraction (chemistry)COVID-19Contaminationbiology.organism_classificationSalut públicaPollutionEcologiaPolyethylene glycol precipitationSARS-CoV-2 Severe Acute Respiratory Syndrome Coronavirus 2WastewaterRNAEC European CommissionRNA extractionPorcine epidemic diarrhea virusPEDV Porcine Epidemic Diarrhea virusWastewater based epidemiologyScience of The Total Environment
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THERAPEUTIC EFFICACY OF MAGNESIUM VALPROATE IN SUCCINIC SEMIALDEHYDE DEHYDROGENASE DEFICIENCY

2012

Succinic semialdehyde dehydrogenase deficiency (SSADHD or gammahydroxybutyric aciduria), a disorder of γ-aminobutyric acid (GABA) metabolism, manifests as a slowly progressive or static encephalopathy. The latter encompasses prominent cognitive dysfunction, neuropsychiatric morbidity and epilepsy.We report safe and effective treatment with MgVPA in an adolescent female with SSADHD and seizures refractory to a broad spectrum of antiepileptics. MgVPA therapy (20 mg/Kg/day) was introduced at 7 years based upon behavioural difficulties and EEG alterations without adverse effects. Therapy was halted at age 13 years, and reintroduced at 14 years, due to new onset complex partial seizures. EEG dem…

Succinic semialdehyde dehydrogenase deficiencySSADHDbusiness.industrySymptomatic seizuresTHERAPEUTIC EFFICACY OF MAGNESIUM VALPROATE IN SUCCINIC SEMIALDEHYDE DEHYDROGENASEStatus epilepticusPharmacologymedicine.diseaseSettore MED/39 - Neuropsichiatria InfantileArticleBroad spectrumEpilepsyNeurodevelopmental disorderConcomitantMAGNESIUM VALPROATEmedicinemedicine.symptomGABAMgVPAbusinessMagnesium Valproate
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