Search results for "Miami"
showing 5 items of 15 documents
N-asyylihemiaminaalit luonnonainesynteeseissä
2015
Monet N–asyylihemiaminaalin sisältävät luonnonaineet toimivat tai ovat potentiaalisia antimikrobisia tai kasvaimia inhiboivia yhdisteitä. N–asyylihemiaminaaliosat tuovat omat haasteensa luonnonaineiden synteeseihin. Niiden vuoksi synteeseissä täytyy kiinnittää erityistä huomiota reaktio-olosuhteiden happamuuteen, käytettyjen reagenssien regio- ja stereoselektiivisiin ominaisuuksiin sekä valmistettavan molekyylin muiden osien vaikutuksista hemiaminaaliosaan. Tässä tutkielmassa on esitelty muutamien luonnonaineiden synteesejä niiden hemiaminaaliosan kannalta sekä tehty havaintoja, kuinka ne käyttäytyvät synteeseissä.
“They’re a little bit squeezed in the middle”: Strategic challenges for innovation in US Metropolitan newspaper organisations
2019
This paper focuses on media innovation among publishers of metropolitan newspapers in the United States, in cities such as San Diego, Boston, Miami, Philadelphia and Dallas. The situation for metropolitan newspapers is difficult, as they fall between national newspapers, which can aim for extending their reach both nationally and globally, and local newspapers, which have a smaller cost structure and can cater to a more limited, and often more engaged, audience community. Our paper demonstrates that there seems to be great awareness of what can be done by US metropolitan newspapers, but managers are struggling with constraints, such as lack of financial and human resources and general organ…
En alas de la danza: Miami Vice y el relato terminal
1989
La televisión ha logrado en Miami Vice (aunque esta solución probablemente será compaginada con otras muchas) realizar un sueño y una paradoja cruel: un relato que no es itinerario, vacío de trayecto, un relato que avanza tanto más frenéticamente cuanto que no se dirige a ningún sitio, porque su punto de llegada está en cada explosión, en cada unidad, idealmente tan pequeña, tan minúscula como los microchips de que se compone la tecnología punta. No es casual -y vale la pena exagerar un poco- que la metáfora del cosmos en formación aflore en algún episodio de la serie. Una galaxia en formación que recuerda vagamente aquellos Lone Drivers de los últimos spots publicitarios de automóviles. "T…
An Insight into Substrate-Dependent Fluorination of some Highly Substituted Alicyclic Scaffolds
2017
The substrate-dependent fluorination of some highly-functionalized cyclopentane derivatives with multiple chiral centers has been investigated. The key steps of the stereocontrolled syntheses are the oxidative cleavage of the ring carbon–carbon double bond of readily available diexo or diendo norbornene β-amino acid derivatives followed by transformation of the resulted dialdehyde stereoisomers by reduction. Finally, substrate-directable chemodifferentiation of different types of hydroxy groups under fluorination procedures gave various densely functionalized alicyclic derivatives or heterocycles.
Preparation of N,O-Aminals as Synthetic Equivalents of H2C=NAr and (H2C=NHAr)+ Ions: Neutral and Acid-promoted Transformations
1988
A general method for the synthesis of N,O-aminals derived from primary aromatic amines is described. The reactivity of these compounds under neutral and acidic conditions has been studied and the title compounds can be envisaged as general purpose H2C=NAr or (H2C=NHAr)+ equivalents. N,O-Aminals have been converted into perhydrotriazines by moderate heating and into bis(4-aminoaryl) methane derivatives or N-benzylarylamines, respectively when heated in acidic media with pH control. Reduction of N, O-acetals with sodium cyanoborohydride has revealed that the C-O bond is broken exclusively in acidic media.