Search results for "Micro"

The small protein TrpM is involved in Streptomyces coelicolor differentiation

miRNome Profiling Detects miR-101-3p and miR-142-5p as Putative Blood Biomarkers of Frailty Syndrome

2022

Frailty is an aging-related pathology, defined as a state of increased vulnerability to stressors, leading to a limited capacity to meet homeostatic demands. Extracellular microRNAs (miRNAs) were proposed as potential biomarkers of various disease conditions, including age-related pathologies. The primary objective of this study was to identify blood miRNAs that could serve as potential biomarkers and candidate mechanisms of frailty. Using the Fried index, we enrolled 22 robust and 19 frail subjects. Blood and urine samples were analysed for several biochemical parameters. We observed that sTNF-R was robustly upregulated in the frail group, indicating the presence of an inflammatory state. …

The

2019

In actinomycetes, antibiotic production is often associated with a morpho-physiological differentiation program that is regulated by complex molecular and metabolic networks. Many aspects of these regulatory circuits have been already elucidated and many others still deserve further investigations. In this regard, the possible role of many small open reading frames (smORFs) in actinomycete morpho-physiological differentiation is still elusive. In Streptomyces coelicolor, inactivation of the smORF trpM (SCO2038) – whose product modulates L-tryptophan biosynthesis – impairs production of antibiotics and morphological differentiation. Indeed, it was demonstrated that TrpM is able to interact w…

A Feasibility Study for the Transition to Electric Mobility in the Island of Favignana

2021

The energy transition and climate neutrality are a short time scenario as climate concerns are rising fast. Small islands are natural microgrids in which the energy transition is subjected to economic and regulatory constraints and highly challenged by technical issues. As a first step, the Mediterranean island of Favignana has been considered in this study, to assess how electric mobility could impact the power system. According to the plans from the local decision makers, the island is moving towards a full public electric mobility in the near term, also due to the participation in the BloRin project. For this reason, a feasibility study about the technical and environmental impact of ele…

Smoking habit and labial microcirculation

2004

Smoking habit is an important risk factor in oral diseases. In the last years, many studies tried to evaluate smoking effects on the microcirculation. It had never been used such a simple not invasive technique, like the video-capillaroscopic one. The aim of the research is to analyse “in vivo”, the microcirculation labial characteristics, and to evaluate the smoking effects by means of computerised videocapillaroscopy techniques. 35 healthy no-smoker patients and 35 healthy smoker patients were examined. The characteristics of the microcirculation in the areas of labial mucous were examined using computerised videomicroscopic techniques. For each patient we evaluated the visibility, the co…

MORPHOLOGIC CHANGES IN THE MICROCIRCULATION INDUCED BY CHRONIC SMOKING HABIT: A VIDEOCAPILLAROSCOPIC STUDY ON THE HUMAN GINGIVAL MUCOSA

2005

PURPOSE: To analyze the gingival characteristics of microcirculation in vivo and to evaluate the effects of smoking by means of computerised videocapillaroscopic techniques. METHODS: 35 healthy non-smokers and 35 healthy smokers were examined. The characteristics of gingival microcirculation were examined using computerized videomicroscopic techniques. For each subject, visibility, course, tortuosity and any images characteristic of capillary loops, besides the possible presence of microhemorrhages, the average caliber of the capillary loops and the number of capillary loops visible per square millimeter were evaluated. The investigation was non-invasive and repeatable for each subject. RES…

Labile nitrogen, carbon, and phosphorus pools and nitrogen mineralization and immobilization rates at low temperatures in seasonally snow-covered soi…

2006

Surface mineral horizons from four ecosystems sampled in the northwestern Italian Alps were incubated at −3 and +3°C to simulate subnivial and early thaw period temperatures for a seasonally snow-covered area. The soil profiles at these sites represent extreme examples of management, grazed meadow (site M) and extensive grazing beneath larch (site L) or naturally disturbed by avalanche and colonized by alder (site A) and the expected forest climax vegetation beneath fir (site F). Changes in labile pools of nitrogen (N) and phosphorus (P) were active at all sites at both temperatures during 14 days of laboratory incubation. Ammonium was the dominant inorganic form of total dissolved N (TDN),…

Between-group competition and human cooperation.

2008

A distinctive feature of human behaviour is the widespread occurrence of cooperation among unrelated individuals. Explaining the maintenance of costly within-group cooperation is a challenge because the incentive to free ride on the efforts of other group members is expected to lead to decay of cooperation. However, the costs of cooperation can be diminished or overcome when there is competition at a higher level of organizational hierarchy. Here we show that competition between groups resolves the paradigmatic ‘public goods’ social dilemma and increases within-group cooperation and overall productivity. Further, group competition intensifies the moral emotions of anger and guilt associated…

The Impact Of Hybrid Infrastructure On Trust, Motivation And Knowledge Sharing In An Intentional Community: A Latvian Case Study

2013

The role of ICT infrastructure in enhancing innovation processes through fostering knowledge and information exchange is a controversial topic in regional science. Opposing views exist, in particular, with regard to two topics: a) the persistence of a specific role of geographical proximity in knowledge exchange processes in the age of global virtual networking; b) the capability of virtual networking to recreate the social assets of a physical community (trust, solidarity?). Existing studies primarily focus on aggregated data, rely on doubtful epistemological assumptions (e.g. the equation of information with knowledge), and neglect several epistemological principles of social cognition (e…

Apple, Ibm e Microsoft in una guerra di segni

2009

L'obiettivo dell'articolo è esplorare come l'immagine contribuisce alla costruzione della brand identity di specifiche organizzazioni e come l'immagine può essere "risifignicata" dall'azione dei concorrenti in un mercato determinato. In particolare, l'articolo si studia la competizione tra tre brand, Ibm, Apple e Microsoft nel mercato dell'information tecnology. Il mio lavoro vuole essere una continuazione del saggio "la via del logo" pubblicato in "Identità visive" di Jean Marie Floch sulla competizione visiva tra Apple e Ibm. Gli strumenti utilizzati sono quelli della sociosemiotica, in particolare dell'analisi plastica e figurativa, lungo più di vent'anni di competizione a partire dal 19…