Search results for "Mineral"
showing 10 items of 2711 documents
Surgical treatment and follow-up of solitary bone cyst of the mandible:a report of seven cases.
2001
We have operated on and followed up seven patients with simple mandibular bone cysts. The clinical data are shown in Table 1. All cysts were asymptomatic, and were found as a result of routine radiographs. They were all in dentulous areas in the mandible (5 in the anterior zone). Only case 5 gave a clear history of trauma in the region of the cyst 7 years before diagnosis. Vitality of the pulp of adjacent teeth was confirmed in all cases except case 6, in whom endodontic orthograde treatment of the teeth included in the lesion zone had previously been done. In all cases, the radiographs showed a unilocular radiotransparent lesion with clearly defined margins
Baseline characteristics and outcome in Romanian patients with Gaucher disease type 1.
2009
Abstract Background/aim To present clinical and genetic characteristics of all Romanian patients with Gaucher disease type 1, in whom specific diagnosis has been confirmed by enzymatic and molecular methods and to analyze their outcome with and without enzymatic replacement therapy (ERT). Patients, methods There are fifty patients (F/M — 1.63/1) with Gaucher disease type 1. Clinical status, haemoglobin, thrombocytes, hepatic/splenic volume, bone mineral density and severity score were assessed at baseline and every six months thereafter. Thirty-nine patients (78%) received imiglucerase (44.4 ± 13.6 U/kg/2 weeks) for 3.1 +/− 1.4 years. Results Based on general prevalence data, our group repr…
Bone Mineral Density and Vitamin D Status in Female and Male Patients with Osteoarthritis of the Knee or Hip
2008
<i>Objective:</i> Osteoporosis (OP), osteoarthritis (OA) and vitamin D deficiency are age-related disorders. We investigated the association between bone mineral density (BMD), vitamin D and OA in patients undergoing total hip or knee replacements. <i>Method:</i> In total, 82 women and 35 men with mean ages of 70 and 68 years, respectively, were recruited for the study. The BMD of the lumbar spine and the proximal femur were measured by dual-energy X-ray absorptiometry. The vitamin D status was assessed by 25(OH)D levels, with a cut-off of ≤30 ng·ml<sup>–1</sup>. <i>Results:</i> In total, 84.7% of the patients had a vitamin D deficiency; 20% o…
Whole-body potassium and bone mineral density up to 30 years after urinary diversion
1998
Objectives To evaluate the long-term effects of different types of urinary diversion on skeletal bone density and whole-body potassium content in patients with an early correction of base excess (<−2.5). Patients and methods The early correction of base excess (<−2.5) is one of the principles of the treatment of patients undergoing urinary diversion at our institution. In 27 patients with urinary diversion, bone mineral density (assessed by dual-photon absorptiometry), whole-body potassium, electrolyte and creatinine levels were determined, and capillary blood gas analysed. The mean time since surgery was 16.8 years in 16 patients with a rectal reservoir, 20.5 years in six patients with a…
Effect of long-term treatment with GH on bone metabolism, bone mineral density and bone elasticity in GH-deficient adults
1998
OBJECTIVE Adults with GH deficiency (GHD) commonly have subnormal bone mineral density (BMD), and have been reported to have an increased risk of fractures. It has been suggested that GH replacement therapy may have beneficial effects on bone in such patients. The aim of this study was to investigate the effects of long-term GH replacement therapy on bone metabolism, BMD and bone elasticity in adults with GHD. DESIGN At the start of the study, 20 adults with GHD were randomized to receive either GH, 0.25 IU/kg/week (the ‘GH group’) or placebo (the ‘placebo group’). After 6 months, patients in the placebo group were switched to GH therapy, and all patients received GH for a further 42 months…
Progression of Coronary Artery Calcification in Predialysis Patients
2006
<i>Background:</i> In patients on dialysis coronary artery calcification (CAC) rapidly proceeds due to impaired mineral metabolism and/or exogenous calcium load. Progression has not been assessed in patients with chronic kidney disease not yet requiring dialysis (CKD patients). In this study, rate and determinants of CAC progression have been evaluated in CKD patients who are exposed to minor derangement of mineral metabolism and calcium load. <i>Methods:</i> Consecutive patients were enrolled. Exclusion criteria were: symptomatic coronary disease, arrhythmia, myocardial infarction, and diabetes. Serum calcium, phosphorus, parathyroid hormone, homocysteine, C-reactiv…
Bone metabolism and clinical study of 44 patients with bisphosphonate-related osteonecrosis of the jaws.
2011
Osteonecrosis of the jaws is a clinical entity described and linked to treatment with bisphosphonates in 2003. Its real incidence is unknown and it could increase due to the large number of patients treated with these drugs, and its cumulative effect on the bone. State of the art knowledge regarding its etiopathogeny, clinical course and suitable treatments is limited. Objectives: To study the clinical characteristics of 44 patients with bisphosphonate-related osteonecrosis of the jaws and the state of their bone mineral metabolism: bone remodeling state, prevalence of fractures, bone mineral density study, and assessment of the different treatment strategies. Design of the Study: Observati…
Mineral mass, size, and estimated mechanical strength of triple jumpers’ lower limb
2001
This study was designed to examine the anticipated strong influence of extreme impact loading on the mineral mass, size, and gross structural properties of triple jumpers' lower limb bones. We compared the bone data obtained with peripheral quantitative computed tomography (pQCT) and dual-energy X-ray absorptiometry (DXA) from 8 Finnish triple jumpers with corresponding data from gender-, age-, height-, and weight-matched nonathletic peers. The volumetric (trabecular) density was significantly higher in the jumpers than in controls (from an average 18% difference at the distal tibia to a 41% difference at the proximal tibia), whereas the cortical density did not differ between groups. The D…
Bone Mineral Density and Long Term Exercise
1993
Evidence in human studies of the association of long term habitual exercise with bone mineral content (BMC) and density (BMD) largely comes from studies in athletes. In young adults, the highest BMC and BMD values have been found in strength and power-trained athletes, while endurance activities such as long distance running and swimming seem less effective with regard to peak bone density. Intensive endurance training may even be associated with amenorrhoea and decreased trabecular bone density in young females. However, after menopause female athletes show greater bone mass indicating that they do not share the accelerated decline in BMC observed in a nonathletic population. Middle-aged a…
Age-dependence of bone material quality shown by the measurement of frequency of resonance in the ulna
1994
In women before and after the age of peak bone mass, identical values of bone mineral density (BMD) can be obtained. However, there is a much higher incidence of osteoporotic fractures in older women. We investigated whether a deterioration of bone material quality with increasing age might contribute to this phenomenon. Material properties of bone tissue can be characterized by the modulus of elasticity, which is correlated to the square of sound transmission velocity. In this study, sound transmission velocity was determined in cortical bone by measuring the frequency of resonance in the ulna in the direction of the bone's longitudinal axis and correcting the values by multiplying by ulna…