Search results for "Miniaturization"

showing 4 items of 44 documents

Flexible design of multifocal metalenses based on autofocused Airy beams

2018

Extreme miniaturization of on-demand optical devices such as ultrathin lenses is currently leading to significant advancements in manufacturing novel materials and nanotechnologies. Flexibility and tunability of engineered layouts enable efficient integration of complex photonic modules. In this regard, here we propose an autofocused Airy (AFA)-based metalens that operates, depending on the molded phase profile, as a multifocal focusing lens, which to the best of our knowledge has not been reported before. To do this, we call attention to the fact that the two conjugate focal points of an AFA beam can be brought into real space by applying a proper convex lens phase profile. Considering ful…

business.industryComputer sciencePhase (waves)Physics::OpticsStatistical and Nonlinear Physics02 engineering and technology021001 nanoscience & nanotechnology01 natural sciencesRayAtomic and Molecular Physics and Opticslaw.invention010309 opticsLens (optics)symbols.namesakeCardinal pointOpticsFourier transformlaw0103 physical sciencesMiniaturizationsymbolsPhotonics0210 nano-technologybusinessBeam (structure)Journal of the Optical Society of America B
researchProduct

In Vivo Molecular Imaging of Somatostatin Receptors in Pancreatic Islet Cells and Neuroendocrine Tumors by Miniaturized Confocal Laser-Scanning Fluor…

2010

The aim of the study was to evaluate real time in vivo molecular imaging of somatostatin receptors (sstrs) using a handheld miniaturized confocal laser scan microscope (CLM) in conjunction with fluorescein-labeled octreotate (OcF) in healthy mice and murine models of neuroendocrine tumors. For CLM a small rigid probe (diameter 7 mm) with an integrated single line laser (488 nm) was used (optical slice thickness 7 μm; lateral resolution 0.7 μm). OcF was synthesized via Fmoc solid-phase peptide synthesis and purified by HPLC showing high-affinity binding to the sstr2 (IC50 6.2 nmol). For in vitro evaluation, rat and human pancreatic cancer cells were used and characterized with respect to its…

medicine.medical_specialtyPathologyConfocalEndocrinology Diabetes and MetabolismClinical BiochemistryMice NudeNeuroendocrine tumorsOctreotideBinding CompetitiveBiochemistryIslets of LangerhansMiceEndocrinologyIn vivoInternal medicinePancreatic cancerCell Line TumormedicineSomatostatin receptor 2AnimalsHumansReceptors SomatostatingeographyMice Inbred BALB Cgeography.geographical_feature_categoryMicroscopy ConfocalMiniaturizationChemistrySomatostatin receptorReverse Transcriptase Polymerase Chain ReactionGene Expression ProfilingBiochemistry (medical)Reproducibility of Resultsmedicine.diseaseIsletFluoresceinsImmunohistochemistryMolecular ImagingNeuroendocrine TumorsEndocrinologyEx vivoThe Journal of Clinical Endocrinology & Metabolism
researchProduct

Three-Year Results of Hydrus Microstent with Phacoemulsification

2019

Abstract We report the 3-year IOP efficacy of the implantation of the Schlemm’s canal Hydrus® Microstent (Ivantis®) combined with phacoemulsification versus phacoemulsification alone

medicine.medical_specialtyTime Factorsgenetic structuresmedicine.medical_treatmentGlaucoma01 natural sciencesCataract03 medical and health sciences0302 clinical medicineOphthalmologymedicineHumansSingle-Blind MethodProspective Studies0101 mathematicsGlaucoma Drainage ImplantsMiniaturizationPhacoemulsificationbusiness.industry010102 general mathematicsGlaucomaGeneral MedicinePhacoemulsificationmedicine.diseaseeye diseasesTreatment Outcome030221 ophthalmology & optometryStentssense organsbusinessFollow-Up Studies
researchProduct

Bodies That Matter: Miniaturisation and the Origin(s) of ‘Art’

2020

Small things matter, especially in the so-called ‘arts’. From the visual arts to music and literature, ‘miniatures’ are a transcultural and transhistorical phenomenon that involves our aesthetic attitudes but also our everyday life, our emotional, social and cognitive life. Miniaturisation characterises our cognitive life and, of course, the ‘cognitive life of things’ that we produce, manipulate and discard. My paper is articulated into two sections: the first gives a quick overview of the miniatures of Homo sapiens, especially those of the paleolithic age, and a brief survey of the very challenging history of miniature-interpretation in twentieth-century philosophy of culture. In the secon…

off-line cognitionMiniaturizationpaleolithic figurineSettore L-FIL-LET/14 - Critica Letteraria E Letterature Comparateanimismliberated embodied simulationperceptual primitive
researchProduct