Search results for "Mining"

showing 10 items of 1730 documents

Improvements and applications of the elements of prototype-based clustering

2018

Clustering or cluster analysis is an essential part of data mining, machine learning, and pattern recognition. The most popularly applied clustering methods are partitioning-based or prototype-based methods. Prototype-based clustering methods usually have easy implementability and good scalability. These methods, such as K-means clustering, have been used for different applications in various fields. On the other hand, prototype-based clustering methods are typically sensitive to initialization, and the selection of the number of clusters for knowledge discovery purposes is not straightforward. In the era of big data, in high-velocity, ever-growing datasets, which can also be erroneous, outl…

random projectionparallel computingknowledge discoveryclustering initializationminimal learning machinedata miningprototype-based clusteringmachine learningkoneoppiminenbig datarinnakkaiskäsittelyklusterianalyysitiedonlouhintarobust clusteringK-means
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Rationale and design of the DARWIN-T2D (DApagliflozin Real World evIdeNce in Type 2 Diabetes): A multicenter retrospective nationwide Italian study a…

2017

Background Randomized controlled trials (RCTs) in the field of diabetes have limitations inherent to the fact that design, setting, and patient characteristics may be poorly transferrable to clinical practice. Thus, evidence from studies using routinely accumulated clinical data are increasingly valued. Aims We herein describe rationale and design of the DARWIN-T2D (DApagliflozin Real World evIdeNce in Type 2 Diabetes), a multicenter retrospective nationwide study conducted at 50 specialist outpatient clinics in Italy and promoted by the Italian Diabetes Society. Data synthesis The primary objective of the study is to describe the baseline clinical characteristics (particularly HbA1c) of pa…

randomized controlled trial; real-life; retrospective study; sodium glucose co-transporter-2 inhibitor; medicine (miscellaneous); endocrinology; diabetes and metabolism; nutrition and dietetics; cardiology and cardiovascular medicineBlood GlucoseTime FactorsGlucosideGlycated Hemoglobin ATime FactorMedicine (miscellaneous)Settore MED/13 - EndocrinologiaEndocrinologyGlucosidesSodium-Glucose Transporter 2Retrospective StudieDiabetes MellitusHumansHypoglycemic AgentsData MiningBenzhydryl CompoundsRandomized controlled trial; Real-life; Retrospective study; Sodium glucose co-transporter-2 inhibitor; Benzhydryl Compounds; Biomarkers; Blood Glucose; Data Mining; Diabetes Mellitus Type 2; Glucosides; Glycated Hemoglobin A; Humans; Hypoglycemic Agents; Italy; Research Design; Retrospective Studies; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Time Factors; Treatment Outcome; Crowdsourcing; Evidence-Based Medicine; Medicine (miscellaneous); Endocrinology Diabetes and Metabolism; Nutrition and Dietetics; Cardiology and Cardiovascular MedicineSodium-Glucose Transporter 2 InhibitorsRetrospective StudiesGlycated HemoglobinBenzhydryl CompoundNutrition and DieteticsEvidence-Based MedicineHypoglycemic AgentSodium-Glucose Transporter 2 InhibitorRandomized controlled trial; Real-life; Retrospective study; Sodium glucose co-transporter-2 inhibitor; Benzhydryl Compounds; Biomarkers; Blood Glucose; Data Mining; Diabetes Mellitus Type 2; Glucosides; Glycated Hemoglobin A; Humans; Hypoglycemic Agents; Italy; Research Design; Retrospective Studies; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Time Factors; Treatment Outcome; Crowdsourcing; Evidence-Based MedicineReal-lifeBiomarkerDiabetes and MetabolismRandomized controlled trial; Real-life; Retrospective study; Sodium glucose co-transporter-2 inhibitor; Benzhydryl Compounds; Biomarkers; Blood Glucose; Data Mining; Diabetes Mellitus Type 2; Glucosides; Glycated Hemoglobin A; Humans; Hypoglycemic Agents; Italy; Research Design; Retrospective Studies; Sodium-Glucose Transporter 2; Time Factors; Treatment Outcome; Crowdsourcing; Evidence-Based Medicine; Medicine (miscellaneous); Endocrinology Diabetes and Metabolism; Nutrition and Dietetics; Cardiology and Cardiovascular MedicineRetrospective studyTreatment OutcomeDiabetes Mellitus Type 2ItalyRandomized controlled trialResearch DesignSodium glucose co-transporter-2 inhibitorCrowdsourcingCardiology and Cardiovascular MedicineBiomarkersType 2Human
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TISSBERT: A benchmark for the validation and comparison of NDVI time series reconstruction methods

2018

[EN] This paper introduces the Time Series Simulation for Benchmarking of Reconstruction Techniques (TISSBERT) dataset, intended to provide a benchmark for the validation and comparison of time series reconstruction methods. Such methods are routinely used to estimate vegetation characteristics from optical remotely sensed data, where the presence of clouds decreases the usefulness of the data. As for their validation, these methods have been compared with previously published ones, although with different approaches, which sometimes lead to contradictory results. We designed the TISSBERT dataset to be generic so that it could simulate realistic reference and cloud-contaminated time series …

reconstruction010504 meteorology & atmospheric sciencesComparaciónComputer scienceNDVIGeography Planning and Development0211 other engineering and technologieslcsh:G1-922Comparison02 engineering and technologycomputer.software_genre01 natural sciencesNormalized Difference Vegetation IndexReconstrucciónBenchmark (surveying)Earth and Planetary Sciences (miscellaneous)datasetStatistic021101 geological & geomatics engineering0105 earth and related environmental sciencesSeries (mathematics)BenchmarkingVegetationBase de datosRelleno de huecoscomparisonGap-fillingProbability distributionData miningReconstructionScale (map)computerlcsh:Geography (General)Datasetgap-fillingRevista de Teledetección
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A meta-analysis of the effect size of rheumatoid arthritis on left ventricular mass: comment on the article by Rudominer et al

2009

We appreciate the work of Rudominer et al, who recently published a report describing the association of rheumatoid arthritis (RA) with increased left ventricular mass.

rheumatoid arthritismedicine.medical_specialtybusiness.industryImmunologymeta-analysisrheumatoid arthritis left ventricular massmedicine.diseaseLeft ventricular massText miningRheumatologyRheumatoid arthritisInternal medicineMeta-analysisCardiologyImmunology and AllergyMedicinePharmacology (medical)business
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A novel microtubule de-stabilizing complementarity-determining region C36L1 peptide displays antitumor activity against melanoma in vitro and in vivo

2015

AbstractShort peptide sequences from complementarity-determining regions (CDRs) of different immunoglobulins may exert anti-infective, immunomodulatory and antitumor activities regardless of the specificity of the original monoclonal antibody (mAb). In this sense, they resemble early molecules of innate immunity. C36L1 was identified as a bioactive light-chain CDR1 peptide by screening 19 conserved CDR sequences targeting murine B16F10-Nex2 melanoma. The 17-amino acid peptide is readily taken up by melanoma cells and acts on microtubules causing depolymerization, stress of the endoplasmic reticulum and intrinsic apoptosis. At low concentrations, C36L1 inhibited migration, invasion and proli…

rho GTP-Binding ProteinsMelanoma ExperimentalAntineoplastic AgentsApoptosisPeptideComplementarity determining regionBiologyEndoplasmic ReticulumMicrotubulesArticleMicePhosphatidylinositol 3-KinasesCell MovementTubulinCell Line TumormedicineAnimalsNeoplasm MetastasisMelanomaPI3K/AKT/mTOR pathwayCell Proliferationchemistry.chemical_classificationMultidisciplinaryInnate immune systemCell growthMelanomaIntrinsic apoptosisPTEN Phosphohydrolasemedicine.diseaseComplementarity Determining RegionsMolecular biologyMitochondriaDisease Models AnimalchemistryCell cultureCancer researchProtein MultimerizationPeptidesProto-Oncogene Proteins c-aktSignal TransductionScientific Reports
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N,N-Dimethyl-N-propylpropan-1-aminium chloride monohydrate

2008

The title compound, C8H20N+·Cl−·H2O, has been prepared by a simple one-pot synthesis route followed by anion exchange using resin. In the crystal structure, the cations are packed in such a way that channels exist parallel to the b axis. These channels are filled by the anions and water molecules, which interact via O—H...Cl hydrogen bonds [O...Cl = 3.285 (3) and 3.239 (3) Å] to form helical chains. The cations are involved in weak intermolecular C—H...Cl and C—H...O hydrogen bonds. The title compound is not isomorphous with the bromo or iodo analogues.

röntgendiffraktioCrystallographyIon exchangeChemistryHydrogen bondGeneral ChemistryCrystal structurekvaternäärinen ammoniumkloridiCondensed Matter Physicscomputer.software_genreChlorideOrganic PapersCrystallographyQD901-999medicineGeneral Materials ScienceData miningquaternary ammonium chloridecomputersingle crystal diffractionmedicine.drug
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In the name of security : Governmentality apparatus in a multilingual mine in Arctic Finland

2021

This critical sociolinguistic study explores how mining work is governed in the name of security in a mine in Arctic Finland. Although the mining industry is dominated by multinational corporations, mines themselves tend to be concentrated in peripheries where a mobile and multilingual workforce is recruited. Mining is a high-risk business: industrial accidents and environmental damage can be severe. Discursive practices play a crucial role in risk management. In this study, the nexus of language, security, and production in mining work is analyzed by applying the Foucauldian concept of 'governmentality'. The data comprise ethnographic observations, work-related documents, and interviews co…

safetyLinguistics and LanguageSociology and Political SciencehallinnointisecurityminingtyöturvallisuusLanguage and LinguisticsgovernmentalitysosiolingvistiikkaHistory and Philosophy of Science0502 economics and businessMultilingualismkaivostyöntekijätmonikielisyysSociologyturvallisuuskulttuurikaivostyöGovernmentality060201 languages & linguisticsetnografiaapparatus05 social sciences06 humanities and the artsdiskurssintutkimusPhilosophyArctic0602 languages and literature8. Economic growthEthnologyvalvonta050203 business & management
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Salt exploitation, communication routes and territory during the Iron Age around the Cabriel river valley

2020

La sal era un recurso fundamental en la economía de las sociedades antiguas y cada vez tenemos más datos sobre su aprovechamiento y explotación durante la Edad del Hierro en ámbito peninsular. La comarca de Requena-Utiel, en el interior de la provincia de Valencia, presenta la mayor abundancia de salinas continentales históricas del territorio valenciano. Por otro lado, en La Manchuela conquense se localiza la importante mina de sal de Minglanilla-La Pesquera. El hallazgo de material arqueológico ibérico en algunas de estas explotaciones sirve como punto de partida para analizar sus características y ver cómo pudieron quedar integradas en el patrón de asentamiento, así como en una densa red…

salt miningRequena-Utiel PlateauArcheologyHistoryRiver valleygeography.geographical_feature_categorySalt mineLandscape ArchaeologySalinas continentalesmeseta de Requena-UtielArchaeologyValencianlanguage.human_languageminería de salSalt evaporation pondsEvaporation pondArqueología IbéricaArqueología del paisajeGeographyIron AgePeninsulalanguageIberian ArchaeologySPAL. Revista de Prehistoria y Arqueología de la Universidad de Sevilla
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The Joint Distribution Criterion and the Distance Tests for Selective Probabilistic Causality

2010

A general definition and a criterion (a necessary and sufficient condition) are formulated for an arbitrary set of external factors to selectively influence a corresponding set of random entities (generalized random variables, with values in arbitrary observation spaces), jointly distributed at every treatment (a set of factor values containing precisely one value of each factor). The random entities are selectively influenced by the corresponding factors if and only if the following condition, called the joint distribution criterion, is satisfied : there is a jointly distributed set of random entities, one entity for every value of every factor, such that every subset of this set that corr…

selective influenceComputer scienceGeneralizationlcsh:BF1-990Value (computer science)systems of random variablescomputer.software_genre050105 experimental psychologyCausality (physics)Set (abstract data type)03 medical and health sciences0302 clinical medicineJoint probability distributionHypothesis and TheoryPsychology0501 psychology and cognitive sciencesstochastically unrelatedGeneral PsychologyDiscrete mathematics05 social sciencesProbabilistic logicexternal factorsstochastic dependencejoint distributionlcsh:PsychologyProbabilistic causalitySum of normally distributed random variablesData miningcomputerRandom variable030217 neurology & neurosurgeryFrontiers in Psychology
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Detecting cellular network anomalies using the knowledge discovery process

2015

Analytical companies unanimously forecast the exponential growth of mobile traffic consumption over the next five years. The densification of a network structure with small cells is regarded as a key solution to meet growing capacity demands. The manual management of a multi-layer network is a very expensive, error prone, and sluggish process. Hence, the automation of the whole life cycle of network operation is highly anticipated. To this aim 3GPP introduces a self-management concept referred to as SON. It is envisioned that SON updates information concerning the latest network conditions through the MDT mecha- nism. MDT enables a network operator to collect radio and service quality measurem…

self-healKDDtoimintahäiriötviatrakenteettomat verkotdata miningtietoliikenneverkotmatkaviestinverkotradio networksanomaly detectionself-organizing networksLTEMDTcell outagehäiriötradioverkot3G-tekniikkasimulointitiedonlouhintalangattomat verkot
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