Search results for "Misa"

Contribution to the study of spray formation

2012

The work of this thesis aims to provide and validate tools useful to study and understand the phenomena involved in the injection of fuel, mainly focused on intra-flow injector. These tools are numeric and simulate the formation of a spray. A first part focuses on zero-dimensional modelling. Models which predict these following characteristics of spray like the spray angle, the spray penetration or the liquid length are compared with experimental data. The conclusions are that zero-dimensional modelling provides good results very quickly in some cases. Although, a better understanding of the influence of cavitation on the spray, which requires an understanding of the intra-flow injector, co…

Kalmbergin kartasto R VII : List 9

1855

Cross-Talk Correction Method for Knee Kinematics in Gait Analysis Using Principal Component Analysis (PCA): A New Proposal

2014

International audience; Background: In 3D gait analysis, the knee joint is usually described by the Eulerian way. It consists in breaking down the motion between the articulating bones of the knee into three rotations around three axes: flexion/extension, abduction/adduction and internal/external rotation. However, the definition of these axes is prone to error, such as the "cross-talk'' effect, due to difficult positioning of anatomical landmarks. This paper proposes a correction method, principal component analysis (PCA), based on an objective kinematic criterion for standardization, in order to improve knee joint kinematic analysis. Methods: The method was applied to the 3D gait data of …

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

2012

BACKGROUND: High plasma HDL cholesterol is associated with reduced risk of myocardial infarction, but whether this association is causal is unclear. Exploiting the fact that genotypes are randomly assigned at meiosis, are independent of non-genetic confounding, and are unmodified by disease processes, mendelian randomisation can be used to test the hypothesis that the association of a plasma biomarker with disease is causal. METHODS: We performed two mendelian randomisation analyses. First, we used as an instrument a single nucleotide polymorphism (SNP) in the endothelial lipase gene (LIPG Asn396Ser) and tested this SNP in 20 studies (20,913 myocardial infarction cases, 95,407 controls). Se…

A Social Spider Optimisation Algorithm for 3D Unmanned Aerial Base Stations Placement

2020

International audience; In recent years, the use of drones as aerial base stations (ABS) has attracted the attention of both scientific and industrial communities as a promising solution to enhance the network coverage. However, their deployment brings out many challenges and restrictions. In this work, we model a realistic, constrained scenario where unmanned aerial vehicles (UAVs) are used as ABSs along with traditional ground base stations (GBSs) to extend their coverage. We propose a scalable and efficient social spider optimization (SSO) algorithm that determines the placement of UAVs and their association with both user equipments (UEs) and GBSs. Extensive computational experiments we…

Color and multispectral image processing for the detection of inflammatory lesions of the stomach

2019

The work presented in this manuscript is part of the ANR project EMMIE. This project aims to develop an innovative multimodal system for the detection of inflammatory lesions in the stomach. To this purpose, a prototype has been developed to be able to acquire NBI endoscopic images and multispectral images during human's antrum exploration. The prototype is made of a standard endoscope and multispectral images.The prototype can acquire two types of data: NBI images and spectra. These two modalities are processed independently. Common image processing features are used to recognize four kind of diseases: active gastritis, chronic gastritis, metaplasia and atrophy. In addition, visual based f…

Telmisartan cardioprotects from the ischaemic/hypoxic damage through a miR‐1‐dependent pathway

2019

The aim of this study was to investigate whether telmisartan protects the heart from the ischaemia/reperfusion damage through a local microRNA-1 modulation. Studies on the myocardial ischaemia/reperfusion injury in vivo and on the cardiomyocyte hypoxia/reoxygenation damage in vitro were done. In vivo, male Sprague-Dawley rats administered for 3 weeks with telmisartan 12 mg/kg/d by gastric gavage underwent ischaemia/reperfusion of the left descending coronary artery. In these rats, infarct size measurement, ELISA, immunohistochemistry (IHC) and reverse transcriptase real-time polymerase chain reaction showed that expressions of connexin 43, potassium voltage-gated channel subfamily Q member …

Stimulation of the AT2 receptor reduced atherogenesis in ApoE−/−/AT1A−/− double knock out mice

2012

AT1 receptor blockers (ARB) and in part ACE inhibitors (ACI) potentially exert beneficial effects on atherogenesis independent of AT1 receptor inhibition. These pleiotropic effects might be related to angiotensin II mediated activation of the AT2 receptor. To analyze this hypothesis we investigated the development of atherosclerosis and the role of ACIs and ARBs in apolipoprotein E-deficient (ApoE(-/-)) mice and in ApoE/AT1A receptor double knockout mice (ApoE(-/-)/AT1A(-/-)). ApoE(-/-) mice and ApoE(-/-)/AT1A(-/-) mice were fed cholesterol-rich diet for 7 weeks. Vascular oxidative stress, endothelial dysfunction, and atherosclerotic lesion formation were evident in ApoE(-/-) mice, but were…

When symptoms become side effects: Development of the side effect attribution scale (SEAS)

2021

Objectives\ud \ud Symptom misattribution is a central process in the nocebo effect but it is not accurately assessed in current side effect measures. We have developed a new measure, the Side Effect Attribution Scale (SEAS), which examines the degree to which people believe their symptoms are treatment side effects.\ud \ud \ud \ud Methods\ud \ud The SEAS was tested in three New Zealand studies: a vaccination sample (n = 225), patients with gout or rheumatoid arthritis (n = 102), and patients switching to a generic medicine (n = 69). The internal reliability of the scale was examined using Cronbach's alpha. To assess validity, the Side Effect Attribution Total Score and Side Effect Attributi…

Victimisation and life satisfaction of gay and bisexual individuals in 44 European countries: the moderating role of country-level and person-level a…

2018

We examined the link between victimisation and life satisfaction for 85,301 gay and bisexual individuals across 44 European countries. We expected this negative link to be stronger when the internalised homonegativity of the victim was high (e.g. because the victim is more vulnerable) and weaker when victimisation occurs in countries that express intolerance towards homosexuality (e.g. because in such contexts victims expect victimisation more and they attribute it to their external environment). Additionally, we expected internalised homonegativity to relate negatively to life satisfaction. Multilevel analyses revealed that victimisation (i.e. verbal insults, threats of violence, minor or …