Search results for "Mitochondrial"
showing 10 items of 919 documents
Détection hypothalamique de l’hyperglycémie : rôle de la dynamique mitochondriale dans la signalisation par les espèces actives de l’oxygène
2011
Etude de la structure génétique des populations du champignon mycorhizogène à arbuscules Glomus intraradices. S’agit-il d’un champignon ubiquiste?
2010
Mitochondrial genotyping of isolates of the arbuscular mycorrhizal fungus "Glomus intraradices" from the isolate collection of the International Bank…
2011
International audience; The culture collection of the International Bank of Glomeromycota (BEG) provides an important service to scientific community and industry by acting as a repository for well-defined AMF isolates which are made available to the public. The most widely-used species has been referred to as "Glomus intraradices", and was recently renamed Rhizophagus irregularis. This species has emerged as a model organism for experimental research and is the subject of the first AMF genome to be sequenced. The only genetic marker that can currently be used to distinguish strains of R. irregularis in field settings is the mitochondrial large subunit (mtLSU). In addition, genetically dist…
Stilbenes and resveratrol metabolites improve mitochondrial fatty acid oxidation defects in human fibroblasts
2014
International audience; Background: Inborn enzyme defects of mitochondrial fatty acid beta-oxidation (FAO) form a large group of genetic disorders associated to variable clinical presentations ranging from life-threatening pediatric manifestations up to milder late onset phenotypes, including myopathy. Very few candidate drugs have been identified in this group of disorders. Resveratrol (RSV) is a natural polyphenol with anti-oxidant and anti-inflammatory effects, recently shown to have beneficial metabolic properties in mice models. Our study explores its possible effects on FAO and mitochondrial energy metabolism in human cells, which are still very little documented.Methods: Using cells …
New molecular aspects of regulation of mitochondrial activity by fenofibrate and fasting
2000
Abstract Fenofibrate and fasting are known to regulate several genes involved in lipid metabolism in a similar way. In this study measuring several mitochondrial enzyme activities, we demonstrate that, in contrast to citrate synthase and complex II, cytochrome c oxidase (COX) is a specific target of these two treatments. In mouse liver organelles, Western blot experiments indicated that mitochondrial levels of p43, a mitochondrial T3 receptor, and mitochondrial peroxisome proliferator activated receptor (mt-PPAR), previously described as a dimeric partner of p43 in the organelle, are increased by both fenofibrate and fasting. In addition, in PPARα-deficient mice, this influence was abolishe…
Evolution des conceptions de l'organisation de l'ADN mitochondrial par des études de la stérilité mâle cytoplasmique des plantes
1985
Notice présente dans BelInra (https://belinra.inra.fr/gestion/catalog.php?categ=isbd&id=83504); il s'agit d'un type de produit dont les métadonnées ne correspondent pas aux métadonnées attendues dans les autres types de produit : DISSERTATION; Evolution des conceptions de l'organisation de l'ADN mitochondrial par des études de la stérilité mâle cytoplasmique des plantes
Analyse de la variabilité génétique mitochondriale et chloroplastique de deux espèces du genre Lupinus (L.Albus et L. Mutabilis)
1988
Notice présente dans BelInra (https://belinra.inra.fr/gestion/catalog.php?categ=isbd&id=90015); il s'agit d'un type de produit dont les métadonnées ne correspondent pas aux métadonnées attendues dans les autres types de produit : DISSERTATION; Analyse de la variabilité génétique mitochondriale et chloroplastique de deux espèces du genre Lupinus (L.Albus et L. Mutabilis)
Sea Urchin Mitochondrial Matrix Contains a 56-kDa Chaperonine-like Protein
1997
Abstract Paracentrotus lividus mitochondrial matrix contains a constitutive hsp of 56-KDa which cross reacts with a serum anti-hsp-60 chaperonine from yeast mitochondria. The localization of hsps preexisting or newly synthesized in different subcellular fractions of gastrula embryos is also analyzed by two-dimensional electrophoresis.
Autophagy
2012
Klionsky, Daniel J. et al.
Glutathione in Cancer Cell Death
2011
Glutathione (L-γ-glutamyl-L-cysteinyl-glycine; GSH) in cancer cells is particularly relevant in the regulation of carcinogenic mechanisms; sensitivity against cytotoxic drugs, ionizing radiations, and some cytokines; DNA synthesis; and cell proliferation and death. The intracellular thiol redox state (controlled by GSH) is one of the endogenous effectors involved in regulating the mitochondrial permeability transition pore complex and, in consequence, thiol oxidation can be a causal factor in the mitochondrion-based mechanism that leads to cell death. Nevertheless GSH depletion is a common feature not only of apoptosis but also of other types of cell death. Indeed rates of GSH synthesis and…