Search results for "Modality"

An Automatic Sleep Scoring Toolbox : Multi-modality of Polysomnography Signals’ Processing

2019

Sleep scoring is a fundamental but time-consuming process in any sleep laboratory. To speed up the process of sleep scoring without compromising accuracy, this paper develops an automatic sleep scoring toolbox with the capability of multi-signal processing. It allows the user to choose signal types and the number of target classes. Then, an automatic process containing signal pre-processing, feature extraction, classifier training (or prediction) and result correction will be performed. Finally, the application interface displays predicted sleep structure, related sleep parameters and the sleep quality index for reference. To improve the identification accuracy of minority stages, a layer-w…

Multi-factorial sicilian modals: a case of continuity in discourse

2008

We intend to analyze a few constructions, in Sicilian (S) and in the variety of Italian spoken in Sicily (IS), involving the modals voliri (S)/volere (IS) “want” and aviri a (S)/dovere (IS) “have to”. They are used to express both modal values, along a deontic→epistemic continuum, and futurity (Sicilian, but not Italian, lacks a synthetic future). Modality has been traditionally defined as the linguistic manifestation of the speaker’s attitude towards his utterance. However, modality does not have an unambiguous treatment and there is no agreement on number and kind of semantic categories that can be completely defined as modals (cf. Bybee et al. 1994; Palmer 2001; Nuyts 2005). From a cogni…

Use of psycho‐oncological services by prostate cancer patients: A multilevel analysis

2020

Abstract Background Cancer patients often suffer from psychological distress. Psycho‐oncological services (POS) have been established in some health care systems in order to address such issues. This study aims to identify patient and center characteristics that elucidate the use of POS by patients in prostate cancer centers (PCCs). Methods Center‐reported certification and patient survey data from 3094 patients in 44 certified PCCs in Germany were gathered in the observational study (Prostate Cancer Outcomes). A multilevel analysis was conducted. Results Model 1 showed that utilization of POS in PCCs is associated with patients’ age (OR = 0.98; 95%‐CI = 0.96‐0.99; P < .001), number of como…

KEYNOTE-975 study design: a Phase III study of definitive chemoradiotherapy plus pembrolizumab in patients with esophageal carcinoma

2021

Despite curative-intent treatment, most patients with locally advanced esophageal cancer will experience disease recurrence or locoregional progression, highlighting the need for new therapies. Current guidelines recommend definitive chemoradiotherapy in patients ineligible for surgical resection, but survival outcomes are poor. Pembrolizumab is well tolerated and provides promising antitumor activity in patients with previously treated, advanced, unresectable esophageal/esophagogastric junction cancer. Combining pembrolizumab with chemoradiotherapy may further improve outcomes in the first-line setting. Here, we describe the design and rationale for the double-blind, Phase III, placebo-co…

Pulmonary infiltrate with characteristic “reversed halo” and “air crescent” signs

2016

Effect of High‐Caloric Nutrition on Survival in Amyotrophic Lateral Sclerosis

2019

International audience; Objective: Weight loss has been identified as a negative prognostic factor in amyotrophic lateral sclerosis, but there is no evidence regarding whether a high-caloric diet increases survival. Therefore, we sought to evaluate the efficacy of a high-caloric fatty diet (HCFD) for increasing survival.Methods: A 1:1 randomized, placebo-controlled, parallel-group, double-blinded trial (LIPCAL-ALS study) was conducted between February 2015 and September 2018. Patients were followed up at 3, 6, 9, 12, 15, and 18 months after randomization. The study was performed at 12 sites of the clinical and scientific network of German motor neuron disease centers (ALS/MND-NET). Eligible…

The polymodal sensory cortex is crucial for controlling lateral postural stability: evidence from stroke patients.

2000

International audience; In modern literature, internal models are considered as a general neural process for resolving sensory ambiguities, synthesising information from disparate sensory modalities, and combining efferent and afferent information. The polymodal sensory cortex, especially the temporoparietal junction (TPJ), is thought to be a nodal point of the network underlying these properties. According to this view, a pronounced disruption of the TPJ functioning should dramatically impair body balance. Surprisingly, little attention has been paid to this possible relationship, which was the subject of investigation in this study. Twenty-two brain-damaged patients and 14 healthy subject…

Balance training versus balance training and foot and ankle mobilization: a pilot randomized trial in community-dwelling older adults

2019

Background: Balance limitations and foot and ankle problems are common in older adults. Objective: To determine the impact of augmented balance training with foot and ankle mobilizations (FAMs) on ...

Effectiveness of a school-based multicomponent program for the treatment of children with ADHD

2002

The objective of this study was to evaluate the efficacy of a multicomponent program for treating attention-deficit/hyperactivity disorder (ADHD) carried out by teachers in a classroom context. Dependent measures included neuropsychological tasks, behavioral rating scales for parents and teachers, direct observation of behavior in the classroom, and academic records of children with ADHD. Fifty children with ADHD participated in the study. The teachers of 29 of the 50 students were trained in the use of behavior modification techniques, cognitive behavior strategies, and instructional management strategies. The other 21 students formed the control group. Parents' and teachers'ratings detec…

Food memory and its relation with age and liking: An incidental learning experiment with children, young and elderly people

2008

International audience; The present study compared incidental learning and food memory in children, young adults and elderly people for three sensory modalities (taste, texture and aroma). The relation of gender and liker-status (i.e. how much we like a product) with food memory was also investigated. Participants received a complete meal including a custard dessert used as target under incidental learning conditions. 24 h later, participants were confronted with a series of samples consisting of the target and slightly modified versions of the target (distractors) and were unexpectedly asked to perform an ‘‘absolute memory’’ (‘‘Did you eat this sample yesterday?’’) and a ‘‘relative memory’…