Search results for "Model"
showing 10 items of 24058 documents
Bending Work Time: Curvilinear Relationship Between Working Time Dimensions and Psychological and Somatic Symptoms.
2020
Objectives Study examines the curvilinear associations of working time dimensions (working hours, time pressure, work schedules, and control of work time and pace) on psychological and somatic symptoms. Methods Representative Finnish Quality-of-Work-Life Surveys conducted in 2003, 2008 and 2013 were restricted to those (N=11,165) regularly working over 10h/week with more than one-year tenure in their job. Generalised additive models were utilised in analysis. Results Working hours had U-shaped relationships with psychosomatic symptoms, while time pressure had a threshold effect. Work pace control had linear effect. The effects of work time control and work schedules were insignificant. Ther…
Qualitative analysis of housing demand using Google trends data
2019
Big data analytics often refer to the breakdown of huge amounts of data into a more readable and useful format. This study utilises Google Trends big data as a proxy for an analysis of housing demand. We employ a qualitative method (fuzzy set/Qualitative Comparative Analysis, fsQCA), instead of a quantitative method, for our estimate and forecast. The empirical results show that fsQCA successfully forecasts seasonal time series, even though the dataset is small in size. Our findings fill the gap in the qualitative and time series forecasting literature, and the forecasting procedure herein also offers a good standard for industry.
From South to North? Mobility of Southern Italian Students at the Transition from the First to the Second Level University Degree
2018
In the last decades, the Italian University System has encountered several structural reforms aimed at making it more internationally competitive. Among them, the introduction of the University financial autonomy has triggered an “internal” competition among Universities to attract students from the entire country. Students’ enrollment at the first level has decreased significantly especially after the economic crisis of 2008, while the students’ migration from the South to the Central and Northern regions of the country has increased. These phenomena have created further inequalities within the country and a cultural and socio-economic loss for the South that does not appear to slow down. …
A Time-Non-Homogeneous Double-Ended Queue with Failures and Repairs and Its Continuous Approximation
2018
We consider a time-non-homogeneous double-ended queue subject to catastrophes and repairs. The catastrophes occur according to a non-homogeneous Poisson process and lead the system into a state of failure. Instantaneously, the system is put under repair, such that repair time is governed by a time-varying intensity function. We analyze the transient and the asymptotic behavior of the queueing system. Moreover, we derive a heavy-traffic approximation that allows approximating the state of the systems by a time-non-homogeneous Wiener process subject to jumps to a spurious state (due to catastrophes) and random returns to the zero state (due to repairs). Special attention is devoted to the cas…
Faktoru investēšana: Jauno pieeju izpēte un testēšana ar starptautisko finanšu tirgus datiem
2016
Finanšu tirgos pastāv dažādas anomālijas, ko klasiskais modelis (CAPM) nespēj izskaidrot. Ir daudz un dažādas teorijas, kas skaidro kāpēc tirgos pastāv viena vai otra anomālija. Viena no teorijām saka, ka anomālijas patiesībā ir faktori un jauni sistemātiskā riska avoti. Pētnieki ir izdalījuši dažus no šiem faktoriem jeb riska avotiem un rezultātā izveidojuši vairāku faktoru modeļus. Maģistra darbā tiek apskatīti faktoru akciju portfeļu ienesīgumi un analizēti aktīvu cenu novērtēšanas modeļi dažādos laika periodos ASV akciju tirgū, kā arī vienā periodā citiem svarīgākajiem pasaules reģionāliem tirgiem. Tiek secināts, ka atsevišķos īsākos periodos faktoru portfeļu rezultāti ir pretēji gaidīt…
Characterization of a novel three-dimensional outgrowth model of human bronchial mucosa
2011
Recently it has been hypothesized that a reactivation of the epithelial-mesenchymal trophic unit (EMTU) of the respiratory mucosa, caused by extensive epithelial damage, may be responsible for the pathogenesis of asthma. However, most research on this subject so far has been limited by the unavailability of in vitro models correctly mimicking the three-dimensional architecture of the properly differentiated human bronchial mucosa. For this reason, we have developed a novel 3D outgrowth model, obtained from bronchial biopsies and composed of both human bronchial epithelial cells (goblet and columnar cells) and fibroblasts with their basement membrane. Here we present the preliminary data obt…
Single-cell analysis of population context advances RNAi screening at multiple levels
2012
Isogenic cells in culture show strong variability, which arises from dynamic adaptations to the microenvironment of individual cells. Here we study the influence of the cell population context, which determines a single cell's microenvironment, in image‐based RNAi screens. We developed a comprehensive computational approach that employs Bayesian and multivariate methods at the single‐cell level. We applied these methods to 45 RNA interference screens of various sizes, including 7 druggable genome and 2 genome‐wide screens, analysing 17 different mammalian virus infections and four related cell physiological processes. Analysing cell‐based screens at this depth reveals widespread RNAi‐induce…
Modified Glasgow Prognostic Score is Associated With Risk of Recurrence in Bladder Cancer Patients After Radical Cystectomy
2015
Recently, many studies explored the role of inflammation parameters in the prognosis of urinary cancers, but the results were not consistent. The modified Glasgow Prognostic Score (mGPS), a systemic inflammation marker, is a prognostic marker in various types of cancers. The aim of the present study was to investigate the usefulness of the preoperative mGPS as predictor of recurrence-free (RFS), overall (OS), and cancer-specific (CSS) survivals in a large cohort of urothelial bladder cancer (UBC) patients.A total of 1037 patients with UBC were included in this study with a median follow-up of 22 months (range 3-60 months). An mGPS = 0 was observed in 646 patients (62.3%), mGPS = 1 in 297 pa…
Current L2 self-concept of Finnish comprehensive school students : The role of grades, parents, peers, and society
2021
L2 (second/foreign language) motivation research in Finland has been scarce. Furthermore, international motivational research has focused more on ideal and ought-to selves, leaving the current L2 self-concept in the background. In the present study, we attempted to address this gap, exploring what shapes L1 (mother tongue) Finnish students' understanding of themselves as users and learners of L2s. Using structural equation modelling, we studied the relationships between students' (n = 1206) current L2 self-concept and parental encouragement, peer pressure, societal expectations, and grades. We further studied which of these factors are the best predictors of students' current L2 self-concep…
Prosody and fluency of Finland Swedish as a second language: Investigating global parameters for automated speaking assessment
2023
This study investigates prosody and fluency of Finland Swedish as a second language (L2). The main objective is to investigate global measures of prosody and fluency as predictors of overall oral proficiency, fluency, and pronunciation ratings. We analyzed parameters related to temporal fluency, timing (based on syllable durations), and f0 change from spontaneous speech produced by 30 native and 235 non-native speakers of Finland Swedish representing proficiency levels from beginner to intermediate. We used pairwise comparisons to investigate the differences between native speech (L1) and L2 samples from different proficiency levels. To study the predictability of ratings with acoustic para…