Search results for "Modeling and Simulation"
showing 10 items of 1561 documents
Network dynamics of eukaryotic LTR retroelements beyond phylogenetic trees
2009
Abstract Background Sequencing projects have allowed diverse retroviruses and LTR retrotransposons from different eukaryotic organisms to be characterized. It is known that retroviruses and other retro-transcribing viruses evolve from LTR retrotransposons and that this whole system clusters into five families: Ty3/Gypsy, Retroviridae, Ty1/Copia, Bel/Pao and Caulimoviridae. Phylogenetic analyses usually show that these split into multiple distinct lineages but what is yet to be understood is how deep evolution occurred in this system. Results We combined phylogenetic and graph analyses to investigate the history of LTR retroelements both as a tree and as a network. We used 268 non-redundant …
Modelling the spatial-temporal progression of the 2009 A/H1N1 influenza pandemic in Chile
2016
A spatial-temporal transmission model of 2009 A/H1N1 pandemic influenza across Chile, a country that spans a large latitudinal range, is developed to characterize the spatial variation in peak timing of that pandemic as a function of local transmission rates, spatial connectivity assumptions for Chilean regions, and the putative location of introduction of the novel virus into the country. Specifically, a metapopulation SEIR (susceptible-exposed-infected-removed) compartmental model that tracks the transmission dynamics of influenza in 15 Chilean regions is calibrated. The model incorporates population mobility among neighboring regions and indirect mobility to and from other regions via th…
Dendrochemical assessment of mercury releases from a pond and dredged-sediment landfill impacted by a chlor-alkali plant.
2016
International audience; Although current Hg emissions from industrial activities may be accurately monitored, evidence of past releases to the atmosphere must rely on one or more environmental proxies. We used Hg concentrations in tree cores collected from poplars and willows to investigate the historical changes of Hg emissions from a dredged sediment landfill and compared them to a nearby control location. Our results demonstrated the potential value of using dendrochemistry to record historical Hg emissions from past industrial activities.
Stochastic dynamical modelling of spot freight rates
2014
Based on empirical analysis of the Capesize and Panamax indices, we propose different continuous-time stochastic processes to model their dynamics. The models go beyond the standard geometric Brownian motion, and incorporate observed effects like heavy-tailed returns, stochastic volatility and memory. In particular, we suggest stochastic dynamics based on exponential Levy processes with normal inverse Gaussian distributed logarithmic returns. The Barndorff-Nielsen and Shephard stochastic volatility model is shown to capture time-varying volatility in the data. Finally, continuous-time autoregressive processes provide a class of models sufficiently rich to incorporate short-term persistence …
Benefits of a dance group intervention on institutionalized elder people: A Bayesian network approach
2018
[EN] The present study aims to explore the effects of an adapted classical dance intervention on the psychological and functional status of institutionalized elder people using a Bayesian network. All participants were assessed at baseline and after the 9 weeks period of the intervention. Measures included balance and gait, psychological well-being, depression, and emotional distress. According to the Bayesian network obtained, the dance intervention increased the likelihood of presenting better psychological well-being, balance, and gait. Besides, it also decreased the probabilities of presenting emotional distress and depression. These findings demonstrate that dancing has functional and …
Exact simulation of first exit times for one-dimensional diffusion processes
2019
International audience; The simulation of exit times for diffusion processes is a challenging task since it concerns many applications in different fields like mathematical finance, neuroscience, reliability horizontal ellipsis The usual procedure is to use discretization schemes which unfortunately introduce some error in the target distribution. Our aim is to present a new algorithm which simulates exactly the exit time for one-dimensional diffusions. This acceptance-rejection algorithm requires to simulate exactly the exit time of the Brownian motion on one side and the Brownian position at a given time, constrained not to have exit before, on the other side. Crucial tools in this study …
The influence of the mean stress on fatigue life of 10HNAP steel under random loading
2001
Abstract This paper contains the results of uniaxial random load fatigue tests with different mean values performed on 10HNAP steel specimens. The experimental fatigue life was compared with the life determined according to different methods of amplitude transformation of the cycles. Cycles were counted with the rain flow algorithm and damage was cumulated with the Palmgren–Miner hypothesis. It has been shown that in the case of “symmetric” stress histories with zero expected values, the mean values of selected cycles do not strongly influence the calculated fatigue life and transformation of the cycle amplitudes; hence, no mean stress correction for cycle mean values different from zero is…
Comparison of analytical methods and AI tools for material characterisation in hot forming
2002
Abstract Hot forming processes probably represent the most ancient of forming operations and what is more they are still today commonly used in modern mechanical industry in order to obtain sound parts, achieving large deformations with a limited required power. Hot metal forming operations are characterised by a large number of physical and thermal phenomena which have to be taken into account in order to model and design the processes themselves. Actually several thermally activated phenomena occur during the forming processes such as recovery, recrystallisation, grain growth, precipitation, allotropic transformations, etc. In this paper the comparison between an analytical method based o…
Analyzing Protein-Protein Spatial-Temporal Dependencies from Image Sequences Using Fuzzy Temporal Random Sets
2008
Total Internal Reflection Fluorescence Microscopy (TIRFM) allows us to image fluorescenttagged proteins near the plasma membrane of living cells with high spatial-temporal resolution. Using TIRFM imaging of GFP-tagged clathrin endocytic proteins, areas of fluorescence are observed as overlapping spots of different sizes and durations. Standard procedures to measure protein-protein colocalization of dual labeled samples threshold the original graylevel images to segment areas covered by different proteins. This binary logic is not appropriate as it leaves a free tuning parameter which can influence the conclusions. Moreover, these procedures rely on simple statistical analysis based on corre…
On the classification of observations structured into groups
1988
The paper is concerned with the problem of classifying a specific group into two populations (insect eggs of the same clutch belonging therefore to the same species). Two approaches, one parametric and the other non-parametric, are described. The classical likelihood ratio procedure is derived. An interpretation and a decomposition of the test criteria is given. A misclassification estimate using the Chernoff–Kullback–Kailath region is provided.