Search results for "Modell"

Stability and Change in Diffusion Model Parameters over Two Years

2021

In recent years, mathematical models of decision making, such as the diffusion model, have been endorsed in individual differences research. These models can disentangle different components of the decision process, like processing speed, speed–accuracy trade-offs, and duration of non-decisional processes. The diffusion model estimates individual parameters of cognitive process components, thus allowing the study of individual differences. These parameters are often assumed to show trait-like properties, that is, within-person stability across tasks and time. However, the assumption of temporal stability has so far been insufficiently investigated. With this work, we explore stability and c…

Modélisation des objets urbains pour l'étude des dynamiques urbaines dans la longue durée

2007

The use of GIS to study the spatial evolution of pre-industrial cities over the "longue durée" requires rigorously formalising heterogeneous data from different sources into robust entities. An initial model using the HBDS (Hypergraph Based Data Structure) method enabled us to distinguish social and spatial features. In this paper we develop a specific model for the temporal dimension. The definition of urban objects using social, spatial and temporal features enhances the study of urban dynamics of change over the "longue durée".

The discovery of new inhibitors of HIF-1 transcriptional activity by virtual screening

2010

Searching for long-lived particles beyond the Standard Model at the Large Hadron Collider

2020

Particles beyond the Standard Model (SM) can generically have lifetimes that are long compared to SM particles at the weak scale. When produced at experiments such as the Large Hadron Collider (LHC) at CERN, these longlived particles (LLPs) can decay far from the interaction vertex of the primary proton–proton collision. Such LLP signatures are distinct from those of promptly decaying particles that are targeted by the majority of searches for new physics at the LHC, often requiring customized techniques to identify, for example, significantly displaced decay vertices, tracks with atypical properties, and short track segments. Given their non-standard nature, a comprehensive overview of LLP…

3D-QSAR study of ligands for two human olfactory receptors

2007

National audience

On critical behaviour in systems of Hamiltonian partial differential equations

2013

Abstract We study the critical behaviour of solutions to weakly dispersive Hamiltonian systems considered as perturbations of elliptic and hyperbolic systems of hydrodynamic type with two components. We argue that near the critical point of gradient catastrophe of the dispersionless system, the solutions to a suitable initial value problem for the perturbed equations are approximately described by particular solutions to the Painlevé-I (P $$_I$$ I ) equation or its fourth-order analogue P $$_I^2$$ I 2 . As concrete examples, we discuss nonlinear Schrödinger equations in the semiclassical limit. A numerical study of these cases provides strong evidence in support of the conjecture.

Meta-Analysis of Mitochondrial DNA Reveals Several Population Bottlenecks during Worldwide Migrations of Cattle

2014

Several studies have investigated the differentiation of mitochondrial DNA in Eurasian, African and American cattle as well as archaeological bovine material. A global survey of these studies shows that haplogroup distributions are more stable in time than in space. All major migrations of cattle have shifted the haplogroup distributions considerably with a reduction of the number of haplogroups and/or an expansion of haplotypes that are rare or absent in the ancestral populations. The most extreme case is the almost exclusive colonization of Africa by the T1 haplogroup, which is rare in Southwest Asian cattle. In contrast, ancient samples invariably show continuity with present-day cattle …

Pluvial flooding in urban areas: the role of surface drainage efficiency

2018

Pluvial flooding in urban areas may derive from the limited or temporarily reduced efficiency of surface drainage, even when the underlying storm sewers are properly designed. This study focuses on the impact of uncertainties in the operational condition of the surface drainage system on pluvial flood hazard. The flood propagation model FLURB-2D is implemented on a selected study area in the town of Genoa (Italy). Synthetic hyetographs based on the Chicago and bivariate copula methods with suitable return periods are used as input. While simulating the design rainfall, inlet operational conditions are varied stochastically using a Monte Carlo approach. Results confirm that microtopography h…

The Occurrence and Dietary Exposure Assessment of Mycotoxins, Biogenic Amines, and Heavy Metals in Mould-Ripened Blue Cheeses

2020

The occurrence and dietary exposure assessment of 16 mycotoxins, 6 biogenic amines (BAs), and 13 metallic elements in blue-veined cheeses (n = 46) is reported. Co-occurrence of mycophenolic acid (&le

Modelling the presence of disease under spatial misalignment using Bayesian latent Gaussian models.

2015

Modelling patterns of the spatial incidence of diseases using local environmental factors has been a growing problem in the last few years. Geostatistical models have become popular lately because they allow estimating and predicting the underlying disease risk and relating it with possible risk factors. Our approach to these models is based on the fact that the presence/absence of a disease can be expressed with a hierarchical Bayesian spatial model that incorporates the information provided by the geographical and environmental characteristics of the region of interest. Nevertheless, our main interest here is to tackle the misalignment problem arising when information about possible covar…