Search results for "Models"
showing 10 items of 8211 documents
L’educazione del giurista contemporaneo
2021
Il tema dell’educazione giuridica presuppone che si risponda alla domanda “che cos’è il diritto?”. Come questa domanda ammette risposte diverse, a seconda dei tempi, dei luoghi e dell’ideologia di chi risponde, allo stesso modo non esiste un modello unico, o un ideal tipo, di educazione giuridica. Il giurista cambia, e deve cambiare, a seconda della pratica giuridica e della cultura giuridica in cui si trova a operare. Una riflessione sull’educazione giuridica non può dunque prescindere dal contesto. Legal education solicits the search for a preliminary answer to the question “what is the law?”. As this latter question allows different answers depending on times, places and personal ideolog…
Desobediencia civil y participación política. Unas cuestiones abiertas para las democracias constitucionales (y la teoría del derecho)
2015
In this article I try to show some problems of the interpretation of civil disobedience as a practice that aims to maintain democratic principles against discriminative legal patterns or oligarchic forces. I will present two doctrines, the Rawlsian (followed by Habermas) and the one proposed recently by supporters of a radical constitutional change through the exercise of “constituent power”. The Rawlsian account a) offers a too stringent model of justification of this type of practice and b) does not recognize the plurality of subjects to which civil disobedience appeal. The supporters of radical constitutional change fall into a form of heterogony of ends. They reject liberal accounts of …
Within the symbolic world of the prehistoric hunters: A GIS-based and 3D model analysis of sites with complexes of linear incisions in western Sicily
2021
Abstract The prehistoric peopling of Sicily has left scattered traces of symbolic activities through well-known rock art expressions in caves and rock shelters located all around the island (among the most significant, the sites of Addaura, Racchio and Genovese). A peculiar phenomenon is the incision of linear signs, often grouped on the same rocky walls, hidden in fissures or placed at the entrance of the underground chambers of caves. In this report, we investigate a sample of these graphic expressions from a spatial and technical point of view. A GIS-based approach presents the territorial pattern providing insight, on a macroscale, into the intentional positioning of the sign complexes.…
A study of temporal estimation from the perspective of the Mental Clock Model.
2009
M. Cardaci's (2000) Mental Clock Model maintains that a task requiring a low mental workload is associated with an acceleration of perceived time, whereas a task requiring a high mental workload is associated with a deceleration. The authors examined the predictions of this model in a musical listening condition in which musical pieces were audible in several structural complexities. To measure the effects of musical complexity on time estimation, the authors used retrospective and prospective time-estimation paradigms. For the retrospective paradigm, the authors invited participants to listen to a musical piece and then estimate its duration. For the prospective paradigm, the authors invit…
Discovery of recurring behavioural sequences in Wistar rat social activity: Possible support to studies on Autism Spectrum Disorders.
2017
This study was undertaken to investigate whether, in rat interactive activities, recurring sequences of behavioural events might be identified and how and to what extent each component of the pair is involved. To this aim, the multivariate temporal-pattern (t-pattern) analysis was applied to the social interactions of 9 pairs of male Wistar rats tested in open field. Interactive activities were classified into intra- and inter-subjects. Quantitative evaluations showed that intra-subject behavioural elements represented 62.37% and inter-subject ones 37.63% of the comprehensive behaviour. T-pattern analysis revealed the presence of 221 different t-patterns organized in four different categori…
Gestalt Theory, Data Decomposition and Functional Architecture in Visual Neuroscience
2013
Attempts to introduce Gestalt theory into the realm of visual neuroscience are discussed on both theoretical and experimental grounds. To define the framework in which these proposals can be defended, this paper outlines the characteristics of a standard model, which qualifies as a received view in the visual neurosciences, and of the research into natural images statistics. The objections to the standard model and the main questions of the natural images research are presented. On these grounds, this paper defends the view that Gestalt psychology and experimental phenomenology provide a contribution to the research into perception by the construction of phenomenological models for an ecolo…
The destiny of the subjectivity and the life of relationship in the globalized financial economic device.
2012
The present contribution intends to introduce to a reflection on the relationship between culture and personality, on the historicity of the contents that structure all the different levels of subjectivity (individual, interpersonal and transpersonal) beginning from the experience of the EATGA Workshop 2011 that took place in Palermo and that hads as its theme “Intersubjective bonds in the globalized economy”. Following studies and research on the role of the cultural phenomena in the formation of the psyche, in the life of relationship and in the work of transcultural analysis, the EATGA Workshop 2011 have introduced important elements of discontinuity. The theme, that structures the exper…
Prognostic significance of p16INK4a alterations and 9p21 loss of heterozigosity in locally advanced laryngeal squamous cell carcinoma
2002
The p16INK4a gene, localized within chromosome 9p21, has been identified as a cyclin-dependent kinase inhibitor and may negatively regulate the cell cycle acting as a tumor suppressor. Genetic alterations involving the 9p21 region are common in human cancers. A consecutive series of 64 untreated patients (median of follow up 53 months) undergoing surgical resection for locally advanced laryngeal squamous-cell carcinomas (LSCCs) has been studied prospectively. Our purpose was to investigate p16 alterations (9p21 allelic loss, hypermethylation and point mutations) and their possible association with clinico-pathological data and flow cytometric variables (DNA-ploidy and S-phase fraction (SPF)…
Multicomponent Antibiofilm Lipid Nanoparticles as Novel Platform to Ameliorate Resveratrol Properties: Preliminary Outcomes on Fibroblast Proliferati…
2023
The well-being of skin and mucous membranes is fundamental for the homeostasis of the body and thus it is imperative to treat any lesion quickly and correctly. In this view, polyphenols might assist and enhance a successful wound healing process by reducing the inflammatory cascade and the production of free radicals. However, they suffer from disadvantageous physico–chemical properties, leading to restricted clinical use. In this work, a complex mixture of PEGylated lipid, Glyceryl monoester, 18-β-Glycyrrhetinic Acid and Menthol was designed to entrap Resveratrol (RSV) as the active ingredient and further produce lipid nanoparticles (LNPs) by homogenization followed by high-freq…
Lipid and apoprotein composition of HDL in partial or complete CETP deficiency
2012
Hyperalphalipoproteinemia, as observed in patients who are either homozygous or heterozygous for cholesteryl ester transfer protein (CETP) deficiency, has been shown to be associated with striking changes in apolipoprotein size distribution, namely, of high-density lipoprotein (HDL) and HDL-like particles. We compared the effect of varying degrees of CETP activity on the HDL apolipoprotein profile in Caucasian CETP-deficient subjects and following pharmacological decrease in CETP activity, using Size Exclusion Chromatography followed by Reverse Phase Protein Array (SEC RPA). The main HDL-associated apolipoproteins (Apo), i.e. ApoA-I, ApoA-II, ApoC-I, and ApoC-III, co-eluted with the HDL pea…