Search results for "Modula"
showing 10 items of 1481 documents
Neuromodulation of chronic headaches: position statement from the European Headache Federation
2013
The medical treatment of patients with chronic primary headache syndromes (chronic migraine, chronic tension-type headache, chronic cluster headache, hemicrania continua) is challenging as serious side effects frequently complicate the course of medical treatment and some patients may be even medically intractable. When a definitive lack of responsiveness to conservative treatments is ascertained and medication overuse headache is excluded, neuromodulation options can be considered in selected cases.Here, the various invasive and non-invasive approaches, such as hypothalamic deep brain stimulation, occipital nerve stimulation, stimulation of sphenopalatine ganglion, cervical spinal cord sti…
A Neural Multi-Agent Architecture for an Autonomous Mobile Robot Control
1999
The aim of this paper is to introduce a multi-agent architecture for an autonomous robot control oriented to obtain high design modularity and high parallelism of decision processes. A multi-agent approach allows us to design several specialized agents and each of them is optimized in order to solve a single part of the whole task. Each agent is able to cooperate with other agent exchanging information, so the robot is able to make the appropriate policy of management to reach a prefixed goal. We tested the proposed architecture with a simple application: an autonomous mobile robot performs object retrieval tasks into unknown structured environments. The robot is not given a priori map of t…
Comprehensive Modeling and Experimental Testing of Fault Detection and Management of a Nonredundant Fault-Tolerant VSI
2015
This paper presents an investigation and a comprehensive analysis on fault operations in a conventional three-phase voltage source inverter. After an introductory section dealing with power converter reliability and fault analysis issues in power electronics, a generalized switching function accounting for both healthy and faulty conditions and an easy and feasible method to embed fault diagnosis and reconfiguration within the control algorithm are introduced. The proposed system has simple and compact implementation. Experimental results operating both at open- and closed-loop current control, obtained using a test bench realized using a dSPACE system and the fault-tolerant inverter protot…
Integrazione di celle fotovoltaiche ibride nel vetromattone
2012
L’invenzione riguarda l’integrazione del vetromattone con celle solari ibride (organiche/inorganiche), conosciute come Dye-sensitized Solar Cell (DSC). La combinazione del vetromattone con le DSC consente di migliorare le prestazioni del prodotto originario rendendolo in grado di produrre energia pulita. Le caratteristiche di trasparenza e isolamento termo-acustico del prodotto possono essere regolate agendo sulla configurazione delle DSC. Il prodotto può essere assemblato a formare pannelli fotovoltaici per la realizzazione di facciate traslucide energeticamente “attive” in varie condizioni luminose (condizioni di luce diffusa o artificiale) e indipendentemente dall’angolo di radiazione so…
Scavenger – A Framework for Efficient Evaluation of Dynamic and Modular Algorithms
2015
Machine Learning methods and algorithms are often highly modular in the sense that they rely on a large number of subalgorithms that are in principle interchangeable. For example, it is often possible to use various kinds of pre- and post-processing and various base classifiers or regressors as components of the same modular approach. We propose a framework, called Scavenger, that allows evaluating whole families of conceptually similar algorithms efficiently. The algorithms are represented as compositions, couplings and products of atomic subalgorithms. This allows partial results to be cached and shared between different instances of a modular algorithm, so that potentially expensive part…
k-Truss Decomposition for Modular Centrality
2018
There is currently much interest in identifying influential spreaders in complex networks due to many applications concerned, such as controlling the outbreak of epidemics and conducting advertisements for commercial products, and so on. A plethora of centrality measures have been proposed over the years based on the topological properties of networks. However, most of these classical centrality measures fail to select the most influential nodes in networks with a modular structure despite that it is an omnipresent property in real-world networks. Few authors have introduced centrality measures tailored to networks with community structure. In a recent work, we have shown that, in this case…
Gl-learning
2016
In this paper, we present a new open-source software library, Gl-learning, for grammatical inference. The rise of new application scenarios in recent years has required optimized methods to address knowledge extraction from huge amounts of data and to model highly complex systems. Our library implements the main state-of-the-art algorithms in the grammatical inference field (RPNI, EDSM, L*), redesigned through the OpenMP library for a parallel execution that drastically decreases execution times. To our best knowledge, it is also the first comprehensive library including a noise tolerance learning algorithm, such as Blue*, that significantly broadens the range of the potential application s…
On t-Conorm Based Fuzzy (Pseudo)metrics
2020
We present an alternative approach to the concept of a fuzzy (pseudo)metric using t-conorms instead of t-norms and call them t-conorm based fuzzy (pseudo)metrics or just CB-fuzzy (pseudo)metrics. We develop the basics of the theory of CB-fuzzy (pseudo)metrics and compare them with “classic” fuzzy (pseudo)metrics. A method for construction CB-fuzzy (pseudo)metrics from ordinary metrics is elaborated and topology induced by CB-fuzzy (pseudo)metrics is studied. We establish interrelations between CB-fuzzy metrics and modulars, and in the process of this study, a particular role of Hamacher t-(co)norm in the theory of (CB)-fuzzy metrics is revealed. Finally, an intuitionistic version of a CB-fu…
No evidence for sequences structurally related to the RB1 gene in the human genome.
1991
The retinoblastoma (RB1) gene is a ubiquitously expressed gene encoding a cell-cycle control protein. Inactivation of this gene plays a crucial role in the development of retinoblastoma, osteosarcoma, and other tumors. In a search for structurally related gene sequences we identified a 5.5-kb BamHI fragment strongly cross-hybridizing with the 5′ end of the RB1 cDNA. Molecular cloning, in situ hybridization, restriction mapping, and sequence analysis identified this DNA segment as the 28S rRNA gene. The absence of other cross-hybridizing sequences suggests that the RB1 gene is not part of a structurally related gene family.
The designer cytokine hyper-interleukin-6 is a potent activator of STAT3-dependent gene transcription in vivo and in vitro.
1999
Interleukin-6 (IL-6) triggers pivotal pathways in vivo. The designer protein hyper-IL-6 (H-IL-6) fuses the soluble IL-6 receptor (sIL-6R) through an intermediate linker with IL-6. The intracellular pathways that are triggered by H-IL-6 are not defined yet. Therefore, we studied the molecular mechanisms leading to H-IL-6-dependent gene activation. H-IL-6 stimulates haptoglobin mRNA expression in HepG2 cells, which is transcriptionally mediated as assessed by run-off experiments. The increase in haptoglobin gene transcription correlates with higher nuclear translocation of tyrosine-phosphorylated STAT3 and its DNA binding. As H-IL-6 stimulates STAT3-dependent gene transcription, we compared t…