Search results for "Modula"
showing 10 items of 1481 documents
Comparación de los resultados radiológicos, clínicos y analíticos de un vástago con cuello modular y su homólogo monobloque en la artroplastia total …
2022
Introducción: La artroplastia total de cadera es uno de los grandes hitos de la ortopedia moderna. Los vástagos con cuellos modulares fueron introducidos con la ventaja teórica de permitir un ajuste más exacto de la anatomía. La hipótesis de nuestro trabajo es que el vástago modular H-MAX M con cuellos intercambiables permite restaurar el offset femoral y la longitud de miembros, de forma más ajustada que con el vástago monobloque homólogo H-MAX S, obteniendo con ello mejores resultados clínico-funcionales sin añadir los riesgos de una elevación sérica de cromo ni cobalto. El objetivo de nuestro trabajo es comparar los resultados radiológicos, clínicos y analíticos de un vástago con cuell…
Safety of Dietary Guanidinoacetic Acid: A Villain of a Good Guy?
2021
Guanidinoacetic acid (GAA) is a natural amino acid derivative that is well-recognized for its central role in the biosynthesis of creatine, an essential compound involved in cellular energy metabolism. GAA (also known as glycocyamine or betacyamine) has been investigated as an energy-boosting dietary supplement in humans for more than 70 years. GAA is suggested to effectively increase low levels of tissue creatine and improve clinical features of cardiometabolic and neurological diseases, with GAA often outcompeting traditional bioenergetics agents in maintaining ATP status during stress. This perhaps happens due to a favorable delivery of GAA through specific membrane transporters (such as…
A highly selective, Hg2+ triggered hydrogelation: modulation of morphology by chemical stimuli
2014
We report the first Hg2+ selective hydrogelation by 4´-[4-(4- aminophenyl)phenyl]-2,2´:6´,2´´-terpyridine. The gel showed remarkable response towards specific chemical agents such as benzo-18-crown-6 ether and K+ which enabled extensive 10 modulation of the gel morphology. peerReviewed
Dabīgu imūnmodulatoru kvalitātes kontroles metožu izvērtējums un stimulējošās iedarbības salīdzinājums ar baktēriju endotoksīnu
2016
Darba mērķis bija raksturot dabīga imūnmodulatora AMP dezamināzes aktivitāti saturoša glikoproteīnu kompleksa (AMPD) darbību in vitro un novērtēt, vai šī iedarbība nav saistīta ar iespējamo endotoksīna (LPS) piesārņojumu. Tika izvērtētas AMPD attīrīšanas metodes, salīdzināta AMPD, LPS un lentināna ietekme uz iekaisuma citokīnu sekrēciju mononukleārajās šūnās, kā arī uz dermas fibroblastu proliferāciju. AMPD frakcijas sastāvs un polisaharīda daļas iespējami strukturālā līdzība ar LPS sarežģīja kvalitātes kontroli. Tāpat kā LPS, AMPD stimulēja TNF un IL-6 produkciju un veicināja dermas fibroblastu proliferāciju ar imūnšūnu sekretēto proteīnu starpniecību. LPS neitralizēšanai izmantojamās met…
Track finding at Belle II
2021
Computer physics communications 259, 107610 (2021). doi:10.1016/j.cpc.2020.107610
Volume I. Introduction to DUNE
2020
Journal of Instrumentation 15(08), T08008 (1-228) (2020). doi:10.1088/1748-0221/15/08/T08008
RESEARCHES ON THE DIGESTERS AND REACTORS WHICH CAN BE USED IN A FARM SCALE BIOGAS PLANT
2014
In the general context of searching integrated system of renewable energy production, this paper present some researches on the reactors and the digesters, as a main part of a biogas plant at a farm scale. After we present the most used types of digesters, we also concentrated over the processes which take place into a digester, one of them being the removal of H2S from biogas (desulphurisation), which can be made by various methods, either biological or chemical, taking place inside or outside the digester. In the case of biological desulphurization outside the digester, we concentrate on the types of reactors which can be used in this case. Beside the well known types of reactors, we pres…
Novel evidences for a role of dopamine as modulator of intestinal motility: a study on mouse distal colon
2014
Parkinson’s disease (PD) is the second most common neurodegenerative disease after Alzheimer’s disease. It has been classically considered that the pathological hallmarks of PD affect primarily the substantia nigra. Nevertheless, it has become increasingly evident that PD is a multicentric neurodegenerative process that affects several neuronal structures outside the substantia nigra, among which is the enteric nervous system (ENS). Pathological alterations within the ENS could be involved in the gastrointestinal (GI) dysfunction frequently encountered by PD patients. Dopamine (DA) seems to be a major candidate for the impairment of GI function in PD since its levels were found to be decrea…
Cannabis Use and the Risk for Psychosis and Affective Disorders.
2019
Objective: This review discusses the relationship between cannabis use and psychotic, bipolar, depressive, and anxiety disorders, as well as suicide. It summarizes epidemiological evidence from cross-sectional and long-term prospective studies and considers possible etiological mechanisms. Methods: Systematic reviews and methodologically robust studies in the field (from inception to February 2019) were identified using a comprehensive search of Medline, PsychINFO, and Embase and summarized using a narrative synthesis. Results: Consistent evidence, both from observational and experimental studies, has confirmed the important role of cannabis use in the initiation and persistence of psychoti…
Short-term impact of a Western diet on the physiology of the peripheral olfactory system
2016
Current feeding behaviors contribute to the epidemic levels of obesity and diabetes observed in Europe and worldwide. Both the quantity and the quality of ingested food are incriminated. Together with other sensory modalities, olfaction is involved in the control of food intake. Olfactory cues can influence eating behaviors, yet the nutritional status and diet can also alter olfactory abilities. Patients with metabolic disorders present impaired olfactory sensitivity which could in turn worsen their eating behaviors.Here we examined the short-term impact of a Western diet enriched in fat and sugar (High Fat High Sugar, HFHS) on the anatomy and physiology of the olfactory epithelium of postn…