Search results for "Modula"

Report on models and guidelines for the collaborative design, development and delivery of SLPs

2021

This document refers to deliverable 6.3 on the development of models and guidelines for the collaborative development and delivery of short learning programs and related mobility. Originally started with an introductory document, based on experience and expertise with joint Erasmus Mundus programmes, the Networked Curriculum Project (NETCU) and the work on the EADTU Mobility Matrix, this document builds further on the experience of the pilots in the ESLP project (WP6) and from other work packages, referring in particular to the comprehensive SLP design guidelines that have been developed (WP4). nonPeerReviewed

Space-by-Time Modular Decomposition Effectively Describes Whole-Body Muscle Activity During Upright Reaching in Various Directions

2017

The modular control hypothesis suggests that motor commands are built from precoded modules whose specific combined recruitment can allow the performance of virtually any motor task. Despite considerable experimental support, this hypothesis remains tentative as classical findings of reduced dimensionality in muscle activity may also result from other constraints (biomechanical couplings, data averaging or low dimensionality of motor tasks). Here we assessed the effectiveness of modularity in describing muscle activity in a comprehensive experiment comprising 72 distinct point-to-point whole-body movements during which the activity of 30 muscles was recorded. To identify invariant modules o…

Skin Immunomodulation during Regeneration: Emerging New Targets

2021

Adipose-Derived Stem Cells (ADSC) are present within the hypodermis and are also expected to play a pivotal role in wound healing, immunomodulation, and rejuvenation activities. They orchestrate, through their exosome, the mechanisms associated to cell differentiation, proliferation, and cell migration by upregulating genes implicated in different functions including skin barrier, immunomodulation, cell proliferation, and epidermal regeneration. ADSCs directly interact with their microenvironment and specifically the immune cells, including macrophages and T and B cells, resulting in differential inflammatory and anti-inflammatory mechanisms impacting, in return, ADSCs microenvironment and …

A Channel-Aware Adaptive Modem for Underwater Acoustic Communications

2021

Acoustic underwater channels are very challenging, because of limited bandwidth, long propagation delays, extended multipath, severe attenuation, rapid time variation and large Doppler shifts. A plethora of underwater communication techniques have been developed for dealing with such a complexity, mostly tailoring specific applications scenarios which can not be considered as one-size-fits-all solutions. Indeed, the design of environment-specific solutions is especially critical for modulations with high spectral efficiency, which are very sensitive to channel characteristics. In this paper, we design and implement a software-defined modem able to dynamically estimate the acoustic channel c…

On the effects of suitably designed space microstructures in the propagation of waves in time modulated composites

2023

In the one-dimensional case, the amplitude of a pulse that propagates in a homogeneous material whose properties are instantaneously changed in time will undergo an exponential increase due to the interference between the reflected and transmitted pulses generated at each sudden switch. Here, we resolve the issue by designing suitable reciprocal PT-symmetric space-time microstructures so that the interference between the scattered waves is such that the overall amplitude of the wave will be constant in time in each constituent material. Remarkably, for the geometries proposed here, a pulse will propagate with constant amplitude regardless of the impedance between the constituent materials,…

Il ruolo della corteccia prefrontale dorsolaterale nella memoria di riconoscimento: uso dellla Stimolazione Magnetica Transcranica per il trattamento…

Il ruolo della corteccia prefrontale dorsolaterale (DLPFC) in compiti di memoria è stato largamente documentato. Una questione ancora molto dibattuta è il grado di lateralizzazione anatomica-funzionale dei processi di controllo esecutivo della DLPFC coinvolti nella memoria di riconoscimento. Il lavoro di tesi indaga le connessioni tra DLPFC e ippocampo mediante l’applicazione di tecniche di neuromodulazione dell’eccitabilità della DLPFC che consentano di accrescere l’attività ippocampale durante compiti di memoria di riconoscimento. I primi tre studi valutano gli effetti inibitori ed eccitatori della rTMS applicata alla DLPFC sulla performance in compiti di memoria di riconoscimento, in div…

Design, synthesis and structure-activity relationship of 2-(3',4',5'-trimethoxybenzoyl)-benzo[b]furan derivatives as a novel class of inhibitors of t…

2009

The biological importance of microtubules in mitosis and cell division makes them an interesting target for the development of anticancer agents. Small molecules such as benzo[b]furans are attractive as inhibitors of tubulin polymerization. Thus, a new class of inhibitors of tubulin polymerization based on the 2-(3′,4′,5′-trimethoxybenzoyl)-benzo[b]furan molecular skeleton, with electron-donating (Me, OMe or OH) or electron-withdrawing (F, Cl and Br) substituents on the benzene ring, was synthesized and evaluated for antiproliferative activity, inhibition of tubulin polymerization and cell cycle effects. Adding a methyl group at the C-3 position resulted in increased activity. The most prom…

COMMUNITY DETECTION IN TRIPARTITE NETWORKS OF UNIVERSITY STUDENT MOBILITY FLOWS

2021

The purpose of this study is to explore how the multimode network approach can be used to analyse network patterns derived from student mobility flows. We define a tripartite network based on a three-mode data structure, consisting of Italian provinces of residence, universities and fields of study, with student exchanges representing the links between them. A comparison of algorithms for detecting communities from tripartite networks based on modularity optimization is provided, revealing relevant information about the phenomenon under analysis over time. The findings are applied to a real dataset containing micro-level longitudinal information on Italian university students’ careers.

Dog-Owner Relationship, Owner Interpretations and Dog Personality Are Connected with the Emotional Reactivity of Dogs

2022

Simple Summary The relationship between owner and the dog affects the dog's attachment behaviors and stress coping. In turn, the quality of the relationship may affect owner's interpretations about their dog's behavior. Here, we assessed dogs' emotional responses from heart rate variability and behavioral changes during five different situations. Dog owners evaluated the emotion (valence and arousal) of their dog after each situation. We found that both negative and positive incidents provoked signs of emotional arousal in dogs. Owners detected the dog's arousal especially during fear- and stress-evoking situations. The dog-owner relationship did not affect owners' interpretation of dogs' e…

Post-exercise heart rate variability : a new approach to evaluation of exercise-induced physiological training load

2015

To improve maximal endurance performance, an optimal physiological training load, i.e. the balance between exercise and recovery, is required. In general, the goal of a single endurance exercise session is to transiently disturb body homeostasis after which a so-called supercompensation, an improvement in performance, can occur if the recovery period is adequate. The physical training load of a single exercise session consists of the combination of exercise intensity and duration. At the present time, there is no single tool to quantify the amount of disturbance of homeostasis that is equal to physiological training load of a single exercise session. Heart rate variability (HRV), the change…