Search results for "Moi"

Contribution of Molecular Structure to Self-Assembling and Biological Properties of Bifunctional Lipid-Like 4-(

2019

The design of nanoparticle delivery materials possessing biological activities is an attractive strategy for the development of various therapies. In this study, 11 cationic amphiphilic 4-(N-alkylpyridinium)-1,4-dihydropyridine (1,4-DHP) derivatives differing in alkyl chain length and propargyl moiety/ties number and position were selected for the study of their self-assembling properties, evaluation of their cytotoxicity in vitro and toxicity on microorganisms, and the characterisation of their interaction with phospholipids. These lipid-like 1,4-DHPs have been earlier proposed as promising nanocarriers for DNA delivery. We have revealed that the mean diameter of freshly prepared nanoparti…

Lapsuuden väkivaltakokemusten yhteys itse ilmoitettuun rikollisuuteen

1997

A comprehensive guide to the physics and usage of PYTHIA 8.3

2022

This manual describes the PYTHIA 8.3 event generator, the most recent version of an evolving physics tool used to answer fundamental questions in particle physics. The program is most often used to generate high-energy-physics collision "events", i.e. sets of particles produced in association with the collision of two incoming high-energy particles, but has several uses beyond that. The guiding philosophy is to produce and reproduce properties of experimentally obtained collisions as accurately as possible. The program includes a wide ranges of reactions within and beyond the Standard Model, and extending to heavy ion physics. Emphasis is put on phenomena where strong interactions play a ma…

Simuloidun jäähdytyksen suppenemislause

2013

Tämä pro gradu -tutkielma käsittelee simuloitu jäähdytys -nimisen kombinatorisen optimointimenetelmän teoriaa ja käytäntöä. Esimerkiksi kuvankäsittelyssä sovelletun algoritmin ideana on löytää annetulla joukolla määritellyn reaaliarvoisen energiafunktion globaali minimikohta sallimalla - ei pelkästään energiaa vähentäviä - vaan myös energiaa kasvattavia siirtymiä lähtöjoukon alkioiden välillä. Tilastolliseen fysiikkaan analogian omaavan, Gibbsin jakauman ominaisuuksiin pohjautuvan menetelm än matemaattisena perustana toimivat epähomogeeniset Markovin ketjut, joiden suppenemista tarkastellaan Dobrushinin kontraktiokerroinmenetelmän avulla. Simuloidun jäähdytyksen suppenemislause, joka takaa …

Kaikki erilaisia - kaikki yksilöitä : lapsivainajan aseman muutos suomalaisessa kuolinilmoituksessa vuosina 1910-2000

2015

Tutkielman tehtävänä on selvittää, kuinka lasten kuolinilmoittaminen on muuttunut Helsingin Sanomissa vuosien 1910–2000 välillä. Tutkielman varsinaiset tutkimuskysymykset on jaettu kahteen osaan. Miten lapsivainajan kuolinilmoittaminen on muuttunut 1900-luvun aikana Suomessa ja kuinka yleistä se on ollut? Sekä toiseksi, miten lasten kuolinilmoittamisen yleistyminen on vaikuttanut ilmoitusten sisältöön? Tutkielmassa tarkastellaan kuolinilmoituksia kulttuurisena konventiona, joka on osa yhteisön kuolemankulttuuria. Kuolemankulttuurilla tarkoitetaan yhteisön tapoja käsitellä ja selittää kuolemaa. Yhteisön kuolemankulttuuri ei ole yhtenäinen kokonaisuus vaan useampien erilaisten kulttuuristen k…

Skriptikielet pelimoottoreissa

2015

Tutkielmassa perehdytään verkkopelien toteutustekniikoihin ja usealla kielellä toteutettuihin ohjelmistoihin. Konstruktiivisessa osassa näiden avulla rakennetaan yksinkertainen ohjelmistokehys nopeaan verkkopelikehitykseen. Kehyksen toimivuutta arvioidaan eri menetelmillä. This thesis studies the implementation of online games and multi-language software development. A simple rapid application development framework for online games is developed based on these studies. The framework's performance is analyzed using various methods.

Advantages of Hyaluronic Acid and Its Combination with Other Bioactive Ingredients in Cosmeceuticals

2021

This study proposes a review on hyaluronic acid (HA) known as hyaluronan or hyaluronate and its derivates and their application in cosmetic formulations. HA is a glycosaminoglycan constituted from two disaccharides (N-acetylglucosamine and D-glucuronic acid), isolated initially from the vitreous humour of the eye, and subsequently discovered in different tissues or fluids (especially in the articular cartilage and the synovial fluid). It is ubiquitous in vertebrates, including humans, and it is involved in diverse biological processes, such as cell differentiation, embryological development, inflammation, wound healing, etc. HA has many qualities that recommend it over other substances used…

Assessment of the moisturizing potential of a two-phase topical care product containing vegetable oils, glycerin, panthenol, and sodium hyaluronate -…

2022

The presence of moisturizing substances and lipid substances determines the integrity of the epidermis cells and their barrier functions because it protects the interior of the body against environmental changes: temperature, humidity, ultraviolet radiation, pollution, and the effects of detergents. In this study, we performed a non-invasive, preliminary evaluation of the effects of a biphasic facial skin care product containing plant oils, hyaluronic acid, glycerin, and panthenol on skin hydration levels and transepidermal water loss compared to a control group using only shea butter. The topical care product formed as a two-phase emulsion was tested. The research was carried out with the …

Metaheuristics meet metamodels : a modeling language and a product line architecture for route optimization systems

2011

Domain Specific Case Tool for ICT-Enabled Service Design

2014

One major problem in service design is the limited availability of information gathered during the development process. In particular, information on end-user requirements is difficult for designers, developers, and maintainers to access. Here, we provide a mechanism that supports the gathering and modeling of various types of information throughout the service and software development life cycle. As various existing tools focus on a particular part of the life cycle, essential information is not available, or it is more difficult to obtain in later stages. The linkage between information collected in the different stages is often lost. The implemented tool support enables the modeling of r…