Search results for "Moi"
showing 10 items of 2109 documents
In situ synthesis of lipopeptides as versatile receptors for the specific binding of nanoparticles and liposomes to solid-supported membranes.
2008
A detailed study of the in situ coupling of small peptides such as CGGH6 (H6) and CGWK8 (K8) to maleimide functionalized phospholipid bilayers is presented. Individually addressable microstructured membranes are employed to unequivocally probe the conjugation. The in situ coupling of peptides via a terminal cysteine moiety to maleimide functionalized phospholipids is shown to be a convenient and versatile way to selectively fabricate peptide-modified phospholipid bilayers serving as specific receptor platforms for functionalized vesicles and nanoparticles. Specific binding of functional vesicles to the peptide-modified bilayers is achieved by either histidine complexation with Ni-NTA-DOGS c…
A letter from Malevich to Semevsky about Kovalevskaya
2022
Abstract The biographical literature on Sofya Vasilyevna Kovalevskaya has to a large extent relied on her own memoirs, published in Vestnik Evropy only months before her death, and an autobiographical story published posthumously in Russkaya Starina. In this paper we present and discuss the full Russian text with English translation of a letter, previously unpublished, from Kovalevskaya's teacher in childhood and adolescence, Iosif Ignatyevich Malevich, to the editor of Russkaya Starina, Mikhail Ivanovich Semevsky, in which he repudiates her depreciation of his role in her schooling, criticizes her self-portrayal, and provides information about her early education which runs counter to part…
Entre alambradas: diario de los campos de concentración de Eulalio Ferrer: du témoignage à la mémoire collective
2009
International audience
La transmission littéraire face à la médiatisation du génocide des Tutsi au Rwanda
2020
International audience; Le rapport de la littérature à la représentation médiatique du génocide au Rwanda paraît poser un problème inédit et révélateur de phénomènes sociaux contemporains méritant d’être questionnés. Dans des sociétés comme la nôtre où l’image apparaît, d’une part, comme un matériau plus accessible, plus illustratif, un outil qui fait plus directement appel à l’affect et au ressenti, capable de déclencher un choc immédiatement, mais aussi, d’autre part, comme le vecteur privilégié des idéologies, la littérature comme medium de construction de la mémoire d’un événement demande à être redéfinie dans ses moyens et sa « poéthique ». Et ce, particulièrement dans l’ère de la « si…
Computer Science Outreach Workshop and Interest Development: A Longitudinal Study
2018
This longitudinal study investigates the impact of an extra-curricular programming workshop in student interest development in computer science. The workshop was targeted at 12–18-year old youngsters. A survey was sent to all previous participants with a known home address; 31.5% responded the survey (n = 197). This data was then combined with pre-workshop survey data, and analyzed with mixed methods. Positive development of interest was discovered for 57% of the respondents, of which nearly all attributed their interest increase to the workshop at least partly (92%). Qualitative inspection revealed that the workshop provided three anchors that facilitated students’ reengagement with progra…
Gold nanostars co-coated with the Cu(II) complex of a tetraazamacrocyclic ligand
2015
The twelve-membered tetraazamacrocyclic ligand L1 bears an appended lipoic acid unit, whose disulphide ring is an efficient grafting moiety for the surface of gold nanostars (GNS). The GNS that were used featured a localized surface plasmon resonance (LSPR) absorption at ∼800 nm, i.e. in the near infrared (NIR). We investigated different approaches for coating them with the Cu(2+) complex of L1. While the direct reaction of [CuL1](2+) with as-prepared GNS led to aggregation, an initial coating step with polyethyleneglycol-thiol (PEG-SH) was found to be advantageous. Displacement reactions were carried out on pegylated GNS either with [CuL1](2+), directly generating [Cun(L1@GNS)](2n+), or wi…
Upon oxidative stress, the antiapoptotic Hsp60/procaspase-3 complex persists in mucoepidermoid carcinoma cells.
2008
Hsp60, a mitochondrial chaperonin highly conserved during evolution, has been found elevated in the cytosol of cancer cells, both in vivo and in vitro, but its role in determining apoptosis during oxidative stress (OS) has not yet been fully elucidated. The aim of the present work was to study the effects of OS on Hsp60 levels and its interactions with procaspase- 3 (p-C3) and p53 in tumor cells. NCI-H292 (mucoepidermoid carcinoma) cells were exposed to various concentrations of hydrogen peroxide (H2O2) for 24 hours. Cell viability was determined by Trypan blue and MTT assays. DNA damage was assessed by the Comet assay, and apoptosis was measured by the AnnexinV cytofluorimetric test. Expos…
Kalmbergin kartasto R III : List 7
1855
Optimization of the preprocessing steps of MEG measurement data in Meggie application
2015
Tutkielma optimoi MEG (magnetoenkefalografia) mittausaineiston esikäsittelyyn, analysointiin ja visualisointiin kehitetyn Meggie-käyttöliittymän esikäsittelyvaiheita pääasiassa lisäämällä mahdollisuuden rinnakkaislaskentaan. Optimointi toimi tutkielman käytännön osuutena ja sen tukena oli kattava lista vaatimuksia. Optimoinnissa suurin osa työstä meni vanhan koodin refaktorointiin, mutta myös käyttöliittymäkomponentteihin tuli pieniä muutoksia ja itse ohjelmaan muutama uusi toiminnallisuus. Teoreettisessa osuudessa keskitytään Meggien nykyiseen tilaan tutkimalla sen arkkitehtuuria, minkä lisäksi tarkastellaan kehitysvaiheita vaatimuslistan pohjalta sekä tuodaan esiin muistinhallinnan ongelm…
Zn(II)-coordination and fluorescence studies of a new polyazamacrocycle incorporating 1H-pyrazole and naphthalene units.
2010
The synthesis and Zn(2+) coordination properties of a new macrocycle (L1) obtained by dipodal (2 + 2) condensation of the polyamine 3-(naphthalen-2-ylmethyl)pentane-1,5-diamine with 1H-pyrazole-3,5-dicarbaldehyde are reported. pH-metric studies show that L1 bears five measurable protonation steps in the 2.0-11.0 pH range. Fluorescence emission studies indicate that the removal of the first proton from the H(5)L1(5+) species leads to a significant decrease in the emission due to a photoinduced electron transfer process. Addition of Zn(2+) promotes a boat-like conformation that approaches both fluorophores and facilitates the formation of an excimer which reaches its highest emission for a 1 …