Search results for "Mono"
showing 10 items of 6843 documents
Expression and Expressional Control of Nitric Oxide Synthases in Various Cell Types
1995
Publisher Summary Nitric oxide (NO) can produce posttranslational modifications of proteins (via ADP ribosylation) and is capable of destroying parasites and tumor cells by inhibiting iron-containing enzymes or directly interacting with the DNA of these cells. In view of this multitude of functions of NO, it is important to understand how cells accomplish and regulate their NO production. Three isozymes of NOS have been identified, and their protein, cDNA, and genomic DNA structures have been elucidated. In humans NOS I, II, and III are encoded by three different genes, located on chromosomes 12, 17, and 7 respectively. The cDNAs for these enzymes have been isolated. All NOS isozymes oxidiz…
Study by EQCM on the voltammetric electrogeneration of poly(neutral red). The effect of the pH and the nature of cations and anions on the electroche…
2003
Generation of poly(neutral red) films has been studied by means of the simultaneous measurements of current–potential and mass–potential curves during cyclic voltammetry (CV) experiments. It has been proved that the presence of molecular oxygen in the solution increases the amount of polymer deposited on the electrode. Otherwise, using the mass/charge ratio it is possible to obtain quantitative information about the electrodeposition by different procedures. It is observed that this ratio decreases when the amount of polymer electrogenerated increases, except when the polymer is not reduced and oxidised after its electrogeneration. The study of poly(neutral red) by CV and quartz crystal mic…
Synthesis, infrared and M�ssbauer characterization and X-ray crystal structure of 1,10-phenanthrolinium tetrachloromethoxy phenylantimonate(V)
1991
The compound has been characterized by X-ray crystal structure determination, Mossbauer and i.r. spectroscopy. It crystallizes in the monoclinic space groupP21/c (No. 14) witha=24.228(4),b=8.335(2),c=23.975(4) A,β=117.83(3)° andZ=8. Least-squares refinement on 3749 observed reflections gave finalR=0.034 (Rw=0.037). The compound is constituted by [(C6H5)SbCl4OMe]− anions andphenH+cations. The coordination polyhedron about Sb is an octahedron (Sb-Cl 2.416(3), Sb-O 1.962(7) and Sb-C 2.138(9) A). The whole structure is characterized by two short contacts (O(1)⋯N(2) 2.76(1) O(2)⋯N(4) 2.75(1) A) involving the methoxy oxygens of the two independent anionic units [(C6H5)SbCl4OMe]− and two nitrogens…
Sesquiterpene lactones from Artemisia lucentica
1997
Abstract The aerial parts of Artemisia lucentica yielded, in addition to several known compounds, a bicyclic monoterpene ketone, two germacranolides, an eudesmanolide, a 10- epi neudesmanolide, a 2-norelemanolide and three bisabolene derivatives. The stereochemistry of a germacranolide, described as 2α-hydroxyartemorin in a previous investigation of the species, has now been corrected and the compound has been renamed lucentolide.
Sesquiterpene lactones from iranian Artemisia species
1993
Abstract The aerial parts of Artemisia turcomanica and A. deserti yielded two new germacranolides, a new guaianolide, and several known mono- and sesquiterpenes.
(1-Adamantyl)methyl glycidyl ether: a versatile building block for living polymerization.
2014
(1-Adamantyl)methyl glycidyl ether (AdaGE) is introduced as a versatile monomer for oxyanionic polymerization, enabling controlled incorporation of adamantyl moieties in aliphatic polyethers. Via copolymerization with ethoxyethyl glycidyl ether (EEGE) and subsequent cleavage of the acetal protection groups of EEGE, hydrophilic linear polyglycerols with an adjustable amount of pendant adamantyl moieties are obtained. The adamantyl unit permits control over thermal properties and solubility profile of these polymers (LCST). Additionally, AdaGE is utilized as a termination agent in carbanionic polymerization, affording adamantyl-terminated polymers. Using these structures as macroinitiators fo…
Antitumor Vaccines Based on Synthetic Mucin Glycopeptides
2011
The interest in tumor-associated glycoconjugate antigens was particularly initiated by Springer, who published in 1984 that glycoproteins on the outer cell-membrane of epithelial tumor cells have an altered glycosylation consisting of the Thomsen-Friedenreich (T-) antigen and its precursor the TN-antigen structure (Springer 1984). He and his coworkers also had found that monoclonal antibodies induced with glycoproteins from tumor cell membranes showed cross-reactivity to desialylated glycophorin A. It was concluded from these observations that the T-and TN-glycoproteins on the epithelial tumor cells must be structurally related to asialoglycophorin A (Springer et al. 1983) (Fig. 11.1a). Gly…
Design and evaluation of sensory systems based on amphiphilic anthraquinones molecular receptors
2015
A new paradigm is described that allows one to create different types of sensors: from highly sensitive ones to practical household devices. Our approach relies on modular molecular receptors incorporating an intensely-colored aminoanthraquinone signaling unit equipped with both hydrophilic and hydrophobic modules, the number and size of which being configured in accordance with the targeted analyte and the sought detection method. An important advantage is the compliance with some principles of green chemistry, avoiding the use of toxic organic solvents. The proper functionalization of the anthraquinone scaffold afforded water-soluble chromoinophores capable of quantifying selectively Hg2+…
Synthesis of polycaprolactone by microwave irradiation ? an interesting route to synthesize this polymer via green chemistry
2003
Poly(e-caprolactone) has become an important biocompatible and biodegradable polymer. Indeed, due to its multiple biomedical applications, the synthesis of polycaprolactone has received increased attention in the past few decades. Moreover, microwave irradiation is a very clean modern technique widely used for green chemistry. Here, several polymers were synthesized by microwave irradiation, without any solvent, using nontoxic, biologically acceptable lanthanide halides as initiators. Reaction times varied between 2 and 90 min. The molecular weights of the obtained polymer products were between 3,000 and 16,000 g/mol. After polymerization, the polycaprolactone polymers were functionalized b…
Thioester-functionalised and oxime-based hexametallic manganese(iii) single-molecule magnets
2017
Two novel hexametallic MnIII complexes of formulae [Mn6(μ3-O)2(H2N-sao)6(3-atpa)2(EtOH)6]·2EtOH·2H2O (1) and [Mn6(μ3-O)2(H2N-sao)6(6-atha)2(EtOH)6]·6EtOH (2) [H2N-saoH2 = salicylamidoxime, 3-hatpa = 3-(acetylthio)propionic acid, 6-hatha = 6-(acetylthio)hexanoic acid] have been synthesised by using thioester-carboxylate ligands and magnetostructurally characterised. 1 crystallises in the triclinic system with space group P and 2 crystallises in the monoclinic system with space group P21/c. The study of the dc and ac magnetic susceptibility reveals single-molecule magnet behaviour for both compounds with spin-ground states S = 12 and S = 4 for 1 and 2, respectively. Hence, 1 and 2 are new mem…