Search results for "Monoglycerides"

showing 4 items of 4 documents

Synthèse et formulation de résines photopolymérisables issues de la biomasse : application pour l'impression Braille

2014

The work of the PhD deals with the synthesis of polymerizable monomers derived from biomass, the study of their photopolymerization and the characterization of the resulting materials. The formulated monomers were tested in a printing method of Braille characters.The monomers were prepared in a two-steps reaction that is simple, economic and environmentally friendly. The first step comprised a reaction between glycerol derivatives (glycerol carbonate or glycidol) and fatty acids. In the second step, the obtained [alpha]-monoglycerides were functionalized to obtain photopolymerizable monomers. The different obtained monomers that bear (meth)acrylate and/or epoxy groups were photopolymerized …

Glycerol[CHIM.POLY] Chemical Sciences/PolymersPhotopolymerization[alpha]-monoglyceridesGlycerol carbonate[ CHIM.POLY ] Chemical Sciences/PolymersAcides gras[CHIM.POLY]Chemical Sciences/PolymersÉpoxyGlycidolBiomasseCarbonate de glycérol(méth)acrylateBiomassBrailleFatty acidsPhotopolymérisation
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Lipid presentation by the protein C receptor links coagulation with autoimmunity.

2021

A lipid-protein autoimmunity target Several autoimmune diseases, including systemic lupus erythematosus and primary antiphospholipid syndrome, are characterized by the presence of antiphospholipid antibodies (aPLs). These molecules can activate the complement and coagulation cascades, which contributes to pathologies such as thrombosis, stroke, and pregnancy complications. Müller-Calleja et al. found that endothelial protein C receptor (EPCR) in complex with lysobisphosphatidic acid (LBPA) is the cell-surface target for aPL and mediates its internalization (see the Perspective by Kaplan). aPL binding to EPCR-LBPA resulted in the activation of tissue factor–mediated coagulation and interfero…

Receptor complexAntigen presentationAutoimmunityEndosomesmedicine.disease_causeArticleAutoimmunityMiceInterferonimmune system diseasesmedicineAnimalsHumansLupus Erythematosus SystemicneoplasmsBlood CoagulationAutoantibodiesAutoimmune diseaseEndothelial protein C receptorAntigen PresentationMultidisciplinaryInnate immune systemLupus erythematosusEndothelial Protein C ReceptorThrombosismedicine.diseaseAntiphospholipid SyndromeImmunity InnateMice Mutant StrainsDisease Models AnimalSphingomyelin PhosphodiesteraseToll-Like Receptor 7ImmunologyAntibodies AntiphospholipidEmbryo LossMonoglyceridesEndothelium VascularLysophospholipidsmedicine.drugScience (New York, N.Y.)
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Mobilization of late-endosomal cholesterol is inhibited by Rab guanine nucleotide dissociation inhibitor

2000

AbstractCholesterol entering cells in low-density lipoproteins (LDL) via receptor-mediated endocytosis is transported to organelles of the late endocytic pathway for degradation of the lipoprotein particles. The fate of the free cholesterol released remains poorly understood, however. Recent observations suggest that late-endosomal cholesterol sequestration is regulated by the dynamics of lysobisphosphatidic acid (LBPA)-rich membranes [1]. Genetic studies have pinpointed a protein, Niemann–Pick C-1 (NPC-1), that is required for the mobilization of late-endosomal/lysosomal cholesterol by an unknown mechanism [2]. Here, we report the removal of accumulated cholesterol by overexpression of the…

HydrolasesEndosomeEndocytic cycleEndosomesCholesterol 7 alpha-hydroxylaseGeneral Biochemistry Genetics and Molecular BiologyCell Line03 medical and health scienceschemistry.chemical_compound0302 clinical medicineHumansGuanine Nucleotide Dissociation Inhibitors030304 developmental biologyNiemann-Pick Diseases0303 health sciencesbiologyAgricultural and Biological Sciences(all)CholesterolBiochemistry Genetics and Molecular Biology(all)Reverse cholesterol transportCholesterol LDLEndocytosisRecombinant ProteinsCell biologyCholesterolchemistryBiochemistryHMG-CoA reductasebiology.proteinMonoglycerideslipids (amino acids peptides and proteins)RabLysophospholipidsLysosomesGeneral Agricultural and Biological Sciences030217 neurology & neurosurgeryLipoproteinCurrent Biology
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Untargeted metabolomics of fresh and heat treatment Tiger nut ( Cyperus esculentus L. ) milks reveals further insight into food quality and nutrition

2017

Tiger nut (Cyperus esculentus L.) is a crop traditionally grown in Valencia Region (Spain) and other temperate and tropical regions in the world, where its tubers are commonly consumed as tiger nut milk (horchata). Because of their nutritive potential and original taste, these products are beginning to spread internationally and, as consequence, analytical procedures to assess nutritional profiles, quality control issues are acquiring increasing relevance. The main objective of this study was to use an advance analytical method and chemometrics tools to determine if the ultra-high temperature (UHT) treatment necessary to extend the shelf life of tiger nut milk would affect the profile of nu…

NutHigh-resolution mass spectrometryHot TemperatureShelf life01 natural sciencesBiochemistryAnalytical ChemistryDiglyceridesBeveragesCropChemometrics0404 agricultural biotechnologyCyperusNutrientTandem Mass SpectrometryTiger nut milkFood QualityCluster AnalysisMetabolomicsPlant OilsFood scienceAmino AcidsCyperusChromatography High Pressure LiquidPrincipal Component AnalysisUntargeted metabolomicsbiologyChemistryTigerFatty Acids010401 analytical chemistryOrganic Chemistryfood and beveragesVitamins04 agricultural and veterinary sciencesGeneral Medicinebiology.organism_classification040401 food science0104 chemical sciencesFood authenticityEmulsifying AgentsLipidomicsMonoglyceridesSugarsFood qualityJournal of Chromatography A
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