Search results for "Mother"

Long-Term Breastfeeding: The Embodied Experiences of Finnish Mothers

2019

Mothers’ experiences constitute a central and widely discussed issue within feminist breastfeeding research. Less is said however, about long-term breastfeeding in relation to embodiment. This article analyses the embodied experiences of Finnish mothers who have breastfed for over a year. Through a feminist lens, and an inductive qualitative content analysis, the written accounts of 39 long-term breastfeeding mothers were analysed, to show how mothers reflect on embodiment while breastfeeding long-term. Mothers described their embodied experiences in relation to four themes: functionality of the body; tiredness; beauty norms; and pleasure. The study reveals their accounts of bodily changes …

First-Line Treatments for Extensive-Stage Small-Cell Lung Cancer With Immune Checkpoint Inhibitors Plus Chemotherapy: A Network Meta-Analysis and Cos…

2022

BackgroundImmune checkpoint inhibitors (ICIs) plus chemotherapy were unlikely to be considered cost-effective compared with chemotherapy as the first-line treatment of patients with extensive-stage small-cell lung cancer (ES-SCLC) in China due to its high costs. However, the cost-effectiveness of the comparison between the regimens of ICIs plus chemotherapy were remained unclear yet. The aim of this study was to evaluate the efficacy and cost-effectiveness of ICIs plus chemotherapy as the first-line treatment for ES-SCLC from the perspective of the Chinese healthcare system.MethodsA network meta-analysis (NMA) was conducted to indirect compare the clinical benefits between the ICIs plus che…

Effects of B-Cell Lymphoma on the Immune System and Immune Recovery after Treatment: The Paradigm of Targeted Therapy

2022

B-cell lymphoma and lymphoproliferative diseases represent a heterogeneous and complex group of neoplasms that are accompanied by a broad range of immune regulatory disorder phenotypes. Clinical features of autoimmunity, hyperinflammation, immunodeficiency and infection can variously dominate, depending on the immune pathway most involved. Immunological imbalance can play a role in lymphomagenesis, also supporting the progression of the disease, while on the other hand, lymphoma acts on the immune system to weaken immunosurveillance and facilitate immunoevasion. Therefore, the modulation of immunity can have a profound effect on disease progression or resolution, which makes the immune syst…

Parenthood and gender inequality : Population-based evidence on the child penalty in Finland

2019

This study presents evidence on the effect of parenthood on labor market outcomes in Finland. We use population-based data drawn from administrative registers and an event study design centered around the birth of the first child using the specification proposed in Kleven et al. (2019b). The study confirms that women encounter large short- and long-term child penalties in gross labor earnings and that penalties are associated with employment participation. Taxes and social security transfers considerably reduce the child penalty, which also varies by the number of children. peerReviewed

Cisplatin plus weekly vinorelbine versus cisplatin plus vinorelbine on days 1 and 8 in advanced non-small cell lung cancer: a prospective randomized …

2008

Summary Purpose A phase III randomized trial was carried out to compare two schedules of the vinorelbine (VNR)–cisplatin (CDDP) regimen in patients with locally advanced unresectable poor prognosis stage IIIB or metastatic stage IV non-small cell lung cancer. The primary endpoints were overall survival (OS) and analysis of toxicity, while secondary endpoints included response rates, time-to-progression (TTP) and quality of life (QoL). Patients and methods Eligible patients were randomized to receive: (a) VNR 25 mg/m 2 on day 1, 8 and 15 plus CDDP 100 mg/m 2 on day 1 every 4 weeks or (b) VNR 30 mg/m 2 on day 1 and 8 plus CDDP 80 mg/m 2 on day 1 every 3 weeks. All patients were chemotherapy-n…

Aktywizowanie rozwoju sprawności słuchania w języku polskim jako ojczystym

2020

The aim of the present article is to present the typology of listening comprehension skills activated during Polish language lessons. What the author claims is that in Polish school two types of listening co-exist, namely: natural and activated. The former resembles conditions of natural communication, since a student assumes the role of text recipient, whereas the latter is a process of teaching the skills of listening comprehension. Based on questions and instructions elicited from selected school handbooks shows in what way the activated type of listening comprehension is taught as a part of Polish as a mother tongue lessons.

"I'm Indiana Jones!": intertextuality and humor in How I Met Your Mother

2012

Intertekstuaalisuus eli tekstienvälisyys on osa kirjallisuuden tutkimusta. Termi tarkoittaa sitä, että yksikään teksti ei ole rakentunut tyhjiössä, vaan siihen ovat vaikuttaneet muut aiemmin kirjoitetut tekstit. Tekstit siis viittaavat toisiinsa jatkuvasti, vaikka aina näitä viittauksia ei lukijat huomaakaan. Intertekstuaalisilla viittauksilla on kuitenkin yleensä jokin tarkoitus uudessa ympäristössään. Ne voivat esimerkiksi korostaa jonkin asian merkitystä, kehottaa lukijoita huomaamaan eroja tai yhtäläisyyksiä kahden tekstin välillä tai ne voivat saattaa jonkin asian naurunalaiseksi. Tämän kandidaatintutkielman tarkoituksena oli tarkastella laadullisten tutkimusmenetelmien keinoin erityis…

Optimizing intravesical chemotherapy in patients with non muscle invasive bladder carcinoma.

2008

Re: Urinary pH is Highly Associated With Tumor Recurrence During Intravesical Mitomycin C Therapy for Nonmuscle Invasive Bladder Tumor

2011

The authors should be congratulated for their attention to basic and open questions on intravesical therapy of nonmuscle invasive bladder cancer. Intravesical delivery of chemotherapy remains partly empirical, and the pharmacokinetics poorly understood. Every attempt to optimize intravesical therapy should be welcomed. Expensive new strategies to deliver an effective therapeutic tumor dose are currently being explored.1,2 It is reasonable (and mandatory) first to consider and study the basic principles of pharmacokinetics. In this retrospective study Maeda et al investigate the role of pH on the efficacy of intravesical mitomycin C (MMC) in vivo. Their experience shows that urinary pH highe…

Adjuvant intravesical therapy in intermediate risk non-muscle invasive bladder cancer (NMIBC) recurring after first cycle of intravesical treatment.

2011

Introduction and objectives The therapeutic management of intermediate risk NMI-BC recurring after intravesical therapy (IT) is not established. Cystectomy will be offered to patients at higher risk of progression but the majority will be retreated by IT. Although some Authors suggest BCG when intravesical chemotherapy (ICH) fails, some patients are retreated by ICH and some others repeat BCG adopted as first-line treatment. Not many studies have been published on this issue. The response to retreatment by intravesical therapy in terms of recurrence-free rate (RFR) and recurrence-free survival (RFS) is analyzed in 179 intermediate-risk patients. Materials and methods Only intermediate-risk …