Search results for "Move"
showing 10 items of 2153 documents
Toxicity of gold-nanoparticles: Synergistic effects of shape and surface functionalization on micromotility of epithelial cells
2010
Nanoparticle exposure is monitored by a combination of two label-free and non-invasive biosensor devices which detect cellular shape and viscoelasticity (quartz crystal microbalance), cell motility and the dynamics of epithelial cell-cell contacts (electric cell-substrate impedance sensing). With these tools we have studied the impact of nanoparticle shape on cellular physiology. Gold (Au) nanoparticles coated with CTAB were synthesized and studied in two distinct shapes: Spheres with a diameter of (43 ± 4) nm and rods with a size of (38 ± 7) nm × (17 ± 3) nm. Dose-response experiments were accompanied by conventional cytotoxicity tests as well as fluorescence and dark-field microscopy to v…
Attachement and spreading of fibroblasts on an RGD peptide-modified injectable hyaluronan hydrogel
2004
Hyaluronan (HA) hydrogels resist attachment and spreading of fibroblasts and most other mammalian cell types. A thiol-modified HA (3,3'-dithiobis(propanoic dihydrazide) [HA-DTPH]) was modified with peptides containing the Arg-Gly-Asp (RGD) sequence and then crosslinked with polyethylene glycol (PEG) diacrylate (PEGDA) to create a biomaterial that supported cell attachment, spreading, and proliferation. The hydrogels were evaluated in vitro and in vivo in three assay systems. First, the behavior of human and murine fibroblasts on the surface of the hydrogels was evaluated. The concentration and structure of the RGD peptides and the length of the PEG spacer influenced cell attachment and spre…
Time scales of adaptive behavior and motor learning in the presence of stochastic perturbations.
2009
In this paper, the major assumptions of influential approaches to the structure of variability in practice conditions are discussed from the perspective of a generalized evolving attractor landscape model of motor learning. The efficacy of the practice condition effects is considered in relation to the theoretical influence of stochastic perturbations in models of gradient descent learning of multiple dimension landscapes. A model for motor learning is presented combining simulated annealing and stochastic resonance phenomena against the background of different time scales for adaptation and learning processes. The practical consequences of the model's assumptions for the structure of pract…
A Compact Representation of Preferences in Multiple Criteria Optimization Problems
2019
A critical step in multiple criteria optimization is setting the preferences for all the criteria under consideration. Several methodologies have been proposed to compute the relative priority of criteria when preference relations can be expressed either by ordinal or by cardinal information. The analytic hierarchy process introduces relative priority levels and cardinal preferences. Lexicographical orders combine both ordinal and cardinal preferences and present the additional difficulty of establishing strict priority levels. To enhance the process of setting preferences, we propose a compact representation that subsumes the most common preference schemes in a single algebraic object. We …
Optimal Placement of Pressure Sensors Using Fuzzy DEMATEL-Based Sensor Influence
2020
[EN] Nowadays, optimal sensor placement (OSP) for leakage detection in water distribution networks is a lively field of research, and a challenge for water utilities in terms of network control, management, and maintenance. How many sensors to install and where to install them are crucial decisions to make for those utilities to reach a trade-off between efficiency and economy. In this paper, we address the where-to-install-them part of the OSP through the following elements: nodes' sensitivity to leakage, uncertainty of information, and redundancy through conditional entropy maximisation. We evaluate relationships among candidate sensors in a network to get a picture of the mutual influenc…
Quantitative Alexandrov theorem and asymptotic behavior of the volume preserving mean curvature flow
2020
We prove a new quantitative version of the Alexandrov theorem which states that if the mean curvature of a regular set in Rn+1 is close to a constant in the Ln sense, then the set is close to a union of disjoint balls with respect to the Hausdorff distance. This result is more general than the previous quantifications of the Alexandrov theorem, and using it we are able to show that in R2 and R3 a weak solution of the volume preserving mean curvature flow starting from a set of finite perimeter asymptotically convergences to a disjoint union of equisize balls, up to possible translations. Here by a weak solution we mean a flat flow, obtained via the minimizing movements scheme. peerReviewed
Dynamic DNA Origami Devices
2018
DNA nanotechnology provides an excellent foundation for diverse nanoscale structures that can be used in various bioapplications and materials research. Among all existing DNA assembly techniques, DNA origami proves to be the most robust one for creating custom nanoshapes. Since its invention in 2006, building from the bottom up using DNA advanced drastically, and therefore, more and more complex DNA-based systems became accessible. So far, the vast majority of the demonstrated DNA origami frameworks are static by nature; however, there also exist dynamic DNA origami devices that are increasingly coming into view. In this review, we discuss DNA origami nanostructures that exhibit controlled…
Empowerment and Employee Well-Being: A Mediation Analysis Study
2021
This study examines the relationship between structural and psychological empowerment and its effects on employees’ psychological, physical, and social well-being. Despite the quantity of previously published works, empirical evidence about these relationships in the workplace is scarce. We developed a mediation model in which structural empowerment predicts employee well-being via psychological empowerment. We based our study on the EU-27 data from the 6th European Working Conditions Survey (EWCS). Data were collected from a questionnaire administered face-to-face to a random sample of employees and the self-employed representative of the working population in the European Union (number of…
Attentional biases toward emotional images in the different episodes of bipolar disorder: an eye-tracking study.
2014
Attentional biases toward emotional information may represent vulnerability and maintenance factors in bipolar disorder (BD). The present experimental study examined the processing of emotional information in BD patients using the eye-tracking technology. Bipolar patients in their different states (euthymia, mania, depression) simultaneously viewed four pictures with different emotional valence (happy, neutral, sad, threatening) for 20 s while their eye movements were monitored. A group of healthy individuals served as the control. The data revealed the following: (i) a decrease in attention to happy images in BD patients in their depressive episodes compared to healthy individuals, and (ii…
Physical exercise adherence in Finnish children using a music mat: a pilot study
2020
A growing number of studies has shown that informal musical activities, such as singing, playing an instrument, and musical play at home, are positively associated with children’s health. This paper examines the associations between fourteen 4–6-year-old children’s and their parents’ exercise activity, children’s musical and their exercise adherence when using a music mat over an eight-week period in the home environment. Our results show that most of the children moved on the mat breezily and briskly. The parents assessed that exercises required balance and movement control more than endurance or strength. Spearman’s rank-order correlation showed a strong, positive correlation between the …