Search results for "Move"

Inhibition of endocannabinoid-degrading enzyme fatty acid amide hydrolase increases atherosclerotic plaque vulnerability in mice

2013

The role of endocannabinoids such as anandamide during atherogenesis remains largely unknown. Fatty acid amide hydrolase (FAAH) represents the key enzyme in anandamide degradation, and its inhibition is associated with subsequent higher levels of anandamide. Here, we tested whether selective inhibition of FAAH influences the progression of atherosclerosis in mice. Selective inhibition of FAAH using URB597 resulted in significantly increased plasma levels of anandamide compared to control, as assessed by mass spectrometry experiments in mice. Apolipoprotein E-deficient (ApoE(-/-)) mice were fed a high-fat, cholesterol-rich diet to induce atherosclerotic conditions. Simultaneously, mice recei…

Experimental virus evolution reveals a role of plant microtubule dynamics and TORTIFOLIA1/SPIRAL2 in RNA trafficking.

2014

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Being-here. Placemaking in a world of movement

2019

How to write an ethnography about something as difficult to understand and translate into words as the existential importance of place for those who experience displacement?Annika Lems masters this...

Jeffrey Herf. Undeclared Wars with Israel : East Germany and the West German Far Left, 1967–1989.

2018

Practical Movements: Kinetic rituals in the Ancient Western Mediterranean

2011

Scholars have studied the long-distance movements of people and goods in Phoenician and Punic society between the eighth and the second centuries BC in considerable depth. However, little attention has been paid to travelling, walking and sailing as common activities in their daily lives. it was through living in and moving through landscapes and seascapes that people constructed their sense of place. Sacred places may have been nodal points in these settings and everyday movements may well have become ritualized. This article develops the idea that journeys to shrines might be considered as pilgrimages and stresses the kinetic aspect of these practices. I suggest that trips to shrines were…

Optical Evaluation of New Designs of Multifocal Diffractive Corneal Inlays

2019

[EN] Purpose. To assess the imaging properties of two different designs of a new concept of corneal inlays whose working principle is based on diffraction. Methods. The quality of the retinal images provided by Diffractive Corneal Inlays (DCIs) was evaluated theoretically in comparison with Small Aperture Corneal Inlay (SACI). ZEMAX OpticStudio software was employed for the simulations in an eye model with different pupil diameters (3.0 mm and 4.5 mm). The employed merit functions in the analysis were the Modulation Transfer Function (MTF), the area under the MTF (MTFa), and the Point Spread Function (PSF). Comparison was made with the SACI at different defocus conditions. Results. The bifo…

The importance of the posterior joint space for functional mandibular movements: A laboratory cross-sectional study

2018

Background: The search for the ideal, healthy and reproducible position of the condyles is of utmost importance for dental diagnosis and treatment. Thus, the objective of this laboratory cross-sectional study was to verify the relationship between the posterior joint space and the mandibular lateral movements. Material and Methods: Dental casts from 15 women and 15 men with normal mastication, 28 natural teeth and no history of temporomandibular disorders or pain, were fabricated and mounted on a fully adjustable articulator. From the maximum intercuspal position, condylar displacement was evaluated and measured on the working and nonworking sides during mandibular lateral movement, both to…

Influence of proprioceptive information on space orientation on the ground and in orbital weightlessness

1989

Conscious space orientation depends on afferent information from different sense organs including the labyrinth, the eyes, tactile cues from the skin, joint receptors, muscle spindles, tendon organs and possibly viscera. An important role is played by impulses from the cervical position receptors in interaction with concomitant information from the otolith system. In order to isolate the effect of cervical position receptors from that of the otolith system, space experiments in orbital weightlessness and in parabolic aircraft flight were performed. It was found that stimulation of the neck receptors in weightlessness markedly influences the perception of the subjective vertical and horizont…

The non-neuronal cholinergic system in peripheral blood cells: Effects of nicotinic and muscarinic receptor antagonists on phagocytosis, respiratory …

2007

Peripheral blood cells express the complete non-neuronal cholinergic system. For example synthesis of acetylcholine and nicotinic as well muscarinic receptors have been demonstrated in leucocytes isolated from human peripheral blood. In the present experiments mononuclear cells and granulocytes were isolated from the peripheral blood to investigate content and synthesis of acetylcholine as well as phenotypic functions like respiratory burst, phagocytosis and migration. Mononuclear cells (T-cells and monocytes) contained 0.36 pmol/10(6) cells acetylcholine, whereas acetylcholine content in granulocytes was 100-fold lower. Acetylcholine synthesis amounted to 23.2+/-4.7 nmol/mg protein/h and 2…

Gaze position reveals impaired attentional shift during visual word recognition in dysfluent readers

2014

Effects reflecting serial within-word processing are frequently found in pseudo- and non-word recognition tasks not only among fluent, but especially among dyslexic readers. However, the time course and locus of these serial within-word processing effects in the cognitive hierarchy (i.e., orthographic, phonological, lexical) have remained elusive. We studied whether a subject’s eye movements during a lexical decision task would provide information about the temporal dynamics of serial within-word processing. We assumed that if there is serial within-word processing proceeding from left to right, items with informative beginnings would attract the gaze position and (micro-)saccadic eye movem…